Testosterone replacement therapy and the risk of prostate cancer - 0 views
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When the level of circulating androgen is below normal, some androgen receptors are inactive, and the secondary downstream effects are decreased. Once androgen receptors within the prostate are saturated, however, increasing testosterone will no longer have an effect
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the saturation point is thought to occur at low physiologic testosterone levels
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Only the subset of individuals with pretreatment testosterone level <250 ng dl−1 had PSA level correlating with free and total testosterone level
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