IL-2: The First Effective Immunotherapy for Human Cancer | The Journal of Immunology - 0 views
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IL-2 is a 15.5-kDa cytokine secreted predominately by Ag-simulated CD4+ T cells, but it can also be produced by CD8+ cells, NK cells, and activated dendritic cells
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The side effects were transient and returned to baseline following treatment
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A generalized capillary leak syndrome was induced by IL-2 in vivo that resulted in interstitial pulmonary infiltrates and substantial weight gain in patients
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