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Nathan Goodyear

Phenotypic expression of autoimmune autistic disorder (AAD): A major subset of autism - 0 views

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    This study proposes an autoimmune component of ASD. The proposed autoimmunity is from the presence of vaccine strain measles virus. Excessive inflammation plays role in this proposed autoimmunity. Samples in this study were taken from serum and CSF
Nathan Goodyear

Vaccines backfire: Veterinary vaccines found to combine into new infectious viruses - 0 views

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    scary result.  Vaccine used in the prevention of ILT in chickens resulted in a new viral strain.  Two different virus strains were used.  These combined and resulted in a brand new viral strain. Apply this to our multi-dose vaccine schedule i.e. MMR
Nathan Goodyear

Apoptosis as a cause of death in measles virus-infected cells. - 0 views

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    Vitamin A induces cell death in measles infected cells
Nathan Goodyear

Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children - The Cochrane Library - Jefferson - Wiley Online Library - 0 views

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    Does Tamiflu work. The evidence says no.  New cochrane review: "The influenza virus-specific mechanism of action proposed by the produces does not fit the clinical evidence".
Nathan Goodyear

Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors | Lung Cellular and Molecular Physiology - 0 views

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    this is a pdf article only and not much is available for public read: estrogen found to have antiviral activity against influenza A in women via ER-beta activation.
Nathan Goodyear

Demystified . . . Human endogenous retroviruses - 0 views

  • HERVs have been inherited by successive generations and it is possible that some have conferred biological benefits
  • However, several HERVs have been implicated in certain cancers and autoimmune diseases
  • HERVs constitute about 1% of the human genome
  • ...16 more annotations...
  • Human endogenous retroviruses (HERVs) represent footprints of previous retroviral infection and have been termed “fossil viruses”
  • HERVs possess a similar genomic organisation to present day exogenous retroviruses such as human immunodeficiency virus (HIV) and human T cell leukaemia virus (HTLV)
  • Retroviruses in effect are retrograde, because the flow of genetic information is reversed compared with the normal pathway of molecular biosynthesis—DNA → RNA → protein. Indeed, all retroviruses necessitate the conversion of viral RNA into a cDNA intermediary, which is catalysed by the enzyme reverse transcriptase
  • Overall, human endogenous retroviruses constitute about 1% of the human genome”
  • some HERVs have been implicated in certain autoimmune diseases and cancers
  • A unit of sugar, phosphate, and base is strictly termed a nucleotide
  • human genes are composed of exons, which are transcribed and translated into amino acids
  • introns, which are interspersed between exons and represent non-translated regions that contribute to the large size of some genes
  • convincing argument for the possible involvement of HERVs in malignancy
  • HERVs may be involved in carcinogenesis by virtue of the expression of HERV mRNA,26 functional proteins,27 or retroviral-like particles
  • They may also be associated with the generation of new promoters29 or the activation of proto-oncogenes
  • inhibition of an effective immune response,
  • encode immunosuppressive proteins
  • “It has been suggested that HERV-K may be important in the progression of testicular germ cell tumours through inhibition of an effective immune response”
  • HERV-K might be important in the pathogenesis of human breast cancer
  • activation of proto-oncogenes of the ras family is common in many tumour types, and some studies have suggested a potential role for HERVs in ras activation
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    good review of HERVs.
trungtamnamkhoa

Impact Of Unimaginable Harms Of Chickens Chicken Prevention - Men's Health Clinic - 1 views

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    The harmful effects of chicken papilloma disease not only stop at physical health but also the spirit of patients is seriously affected. Patients may be depressed, mentally in crisis when they know that they can follow them all their lives. Chicken ridge is considered the undeniable obsession of men. Referring to this disease, many boys are bored, because once they get sick, the chicken's neck often hangs and leaves many harms. Dr. Vo Duy Tam said, "The chicken's crest is a sexually transmitted disease caused by HPV (Human Papilloma Virus) - The Virus causes human papilloma. Currently there are more than 130 HPV types that have been discovered, among them, the ones that often cause genital warts are types 6, 11, 16, and 18.
Nathan Goodyear

Could Curbing Runaway Immune Responses Treat COVID-19? | The Scientist Magazine® - 0 views

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    Ah...the COVID19 virus and the cytokine storm.
fnfdoc

Coronavirus: A Complete Guide To COVID-19 - Health Blog - 0 views

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    The name coronavirus is derived from the Latin word corona meaning crown, Coronaviruses are a large family of viruses that infects the lungs
Nathan Goodyear

Editorial: Cytokine-Mediated Organ Dysfunction and Tissue Damage Induced by Viruses - 1 views

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    Influenza and other virus' induce cytokine production i.e. cytokine storm via TLR
pharmacybiz

Avacta Halts Sale Of Covid-19 Rapid Antigen LFT - 0 views

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    Britain's biotech firm Avacta Group on Monday (January 10) announced halting sales of its Covid-19 rapid antigen lateral flow test AffiDX to replace antibodies in the device and increase its ability to diagnose the Omicron variant. The company stated that AffiDX is capable of detecting Omicron when the virus is present in high numbers in samples, but the sensitivity of the test reduces at lower viral loads. The performance of all rapid antigen tests came under scanner in wake of a large number of mutations in the Omicron variant. AffiDX contains both a proprietary Affimer reagent and a commercially available antibody. The Affimer reagent detects the Omicron variant with the same sensitivity as the Delta variant, and performance of the antibody is paired with the Affimer reagent in the test. This has been affected by the additional Omicron mutations, the firm said. Alastair Smith, chief executive of Avacta Group, said: "Our determination to only provide high quality, high performance diagnostic tests has led us to the correct decision to pause all marketing of the AffiDX® lateral flow antigen test. We have, of course, been unable to market the product in the UK since October 2021, as the product continues to await approval under the new CTDA regulatory process.
pharmacybiz

England To Reopen Temporary Field Hospitals For Inpatients - 0 views

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    England is set to reopen temporary field hospitals to contain a possible overspill of inpatients due to a surge in coronavirus cases, the national health service said Thursday. Fuelled by the highly contagious Omicron variant, daily cases have ballooned, standing at more than 183,000 on Wednesday. NHS England said it would start building the structures in the grounds of eight hospitals in cities including London, Bristol and Leeds from this week, with each designed to house around 100 extra patients. "Given the high level of Covid-19 infections and increasing hospital admissions, the NHS is now on a war footing," National medical director Stephen Powis said. The extra beds are designed for patients who are recovering from illnesses, including those who no longer have Covid, to free up space and staff to treat large numbers of virus cases.
pharmacybiz

Paxlovid : MHRA Approves Second Oral Covid-19 Antiviral - 0 views

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    UK regulator has approved a second oral antiviral for early treatment of Covid-19 in high-risk adults, after molnupiravir. The Medicines and Healthcare products Regulatory Agency (MHRA) gave its nod for a new treatment called Paxlovid (PF-07321332 and ritonavir), after finding it safe and effective at reducing the risk of hospitalisation and death in people diagnosed with mild Covid-19 infection. Developed by Pfizer, Paxlovid prevents the multiplying of virus, helping the body to overcome the infection. A clinical trial for the treatment in high risk individuals revealed that a five-days course of Paxlovid reduces the risk of hospitalisation and death by 89 per cent. It further revealed that Paxlovid is most effective when taken in the early stage of infection. Dr June Raine, MHRA chief executive, said: "We now have a further antiviral medicine for the treatment of Covid-19 that can be taken by mouth rather than administered intravenously. This means it can be administered outside a hospital setting, before Covid-19 has progressed to a severe stage."
Nathan Goodyear

The Use of a Sensitive Equilibrium Dialysis Method for the Measurement of Free Testosterone Levels in Healthy, Cycling Women and in Human Immunodeficiency Virus-Infected Women - 0 views

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    evaluation via equilibrium dialysis found free testosterone in men to be only 2-3% with these levels being even smaller in women.  
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