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Contents contributed and discussions participated by Nathan Goodyear

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Nathan Goodyear

Oxidative stress and neurotoxicity. [Chem Res Toxicol. 2008] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...18052107

oxidative stress mitochondria neurodegenerative disease Parkinson's Alzheimer's Huntington's ALS MS

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  • Nathan Goodyear on 07 Feb 11
     
    Great article on how oxidative stress, and thus mitochondrial dysfunction, are at the core of neurodegenerative diseases
Nathan Goodyear

Mitochondrial DNA damage and repair in neurodegene... [DNA Repair (Amst). 2008] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...18463003

mitochondria aging neurodegenerative disease Alzheimer's Parkinson's Huntington's ALS

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  • Nathan Goodyear on 07 Feb 11
     
    mitochondria dysfunction at core of aging and neurodegenerative disease
Nathan Goodyear

Mitochondria and neurodegeneration. [Biosci Rep. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17486441

mitochondria neurodegeneration

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  • Nathan Goodyear on 07 Feb 11
     
    mitochondria dysfunction and contribution to neurodegenerative disease
Nathan Goodyear

Mitochondria, metabolic disturbances, oxidative st... [J Neurol Sci. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17462670

mitochondria Coq10 kynurenine neurodegenerative disease Parkinson's Alzheimer's Huntington's

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  • Nathan Goodyear on 07 Feb 11
     
    Great article on CoQ10, mitochondrial function, the kynurenine system and neurodegenerative diseases
Nathan Goodyear

Ubiquinone (coenzyme q10) and mitochondria in oxid... [Biol Signals Recept. 2001 May-Au... - 0 views

www.ncbi.nlm.nih.gov/...11351130

CoQ10 mitochondria oxidative stress Parkinson's neurodegenerative disease

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  • Nathan Goodyear on 07 Feb 11
     
    Very good discussion on CoQ10, oxidative stress, and Parkinson's disease
Nathan Goodyear

Coenzyme Q10 reverses pathological phenotype and r... [Neurology. 2001] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...11502923

CoQ10

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  • The authors conclude that muscle CoQ10 deficiency can be corrected by supplementation of CoQ10, which appears to stimulate mitochondrial proliferation and to prevent apoptosis.
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 supplementation shown to resolve familial CoQ10 deficiency
Nathan Goodyear

Mitochondrial dysfunction and oxidative damage in ... [J Bioenerg Biomembr. 2004] - Pub... - 0 views

www.ncbi.nlm.nih.gov/...15377876

mitochondrial dysfunction CoQ10 neurodegenerative diseases

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  • he increasing evidence that Parkinson's disease is associated with abnormalities in the electron transport gene as well as oxidative damage
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 useful to improve mitochondrial function and thus treatment of neurodegenerative diseases
Nathan Goodyear

Coenzyme Q10 in the central nervous system and its... [Mol Aspects Med. 1997] - PubMed ... - 0 views

www.ncbi.nlm.nih.gov/...9266519

CoQ10 neurodegenerative disease

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  • These findings suggest that coenzyme Q10 might be useful in treating neurodegenerative diseases.
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 useful in treating neurodegenerative diseases
Nathan Goodyear

Mitochondrial disorders. [Curr Opin Neurol. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17885446

mitochondrial neurodegenerative disease

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    mitochondrial medicine and contribution to neurodegenerative diseases
Nathan Goodyear

Bioenergetic and antioxidant properties of coenzym... [Mol Biotechnol. 2007] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...17914161

CoQ10 antioxidant

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  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 is antioxidant and is beneficial in atherosclerosis
Nathan Goodyear

Coenzyme Q10 and statins: biochemical and clinical... [Mitochondrion. 2007] - PubMed re... - 0 views

www.ncbi.nlm.nih.gov/...17482884

Statins CoQ10

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  • physicians should be aware of this drug-nutrient interaction and be vigilant to the possibility that statin drugs may, in some cases, impair skeletal muscle and myocardial bioenergetics.
  • Nathan Goodyear on 07 Feb 11
     
    Statins not good for those who have CoQ10 dysfunction
Nathan Goodyear

Mitochondrial medicine for aging and neurodegenera... [Neuromolecular Med. 2008] - PubM... - 0 views

www.ncbi.nlm.nih.gov/...18566920

mitochondrial medicine aging neurodegeneratve disease

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  • This article discusses critical issues of mitochondria causing dysfunction in aging and neurodegenerative diseases, and discusses the potential of developing mitochondrial medicine, particularly mitochondrially targeted antioxidants, to treat aging and neurodegenerative diseases.
  • Nathan Goodyear on 07 Feb 11
     
    Great review of mitochondrial medicine to treat age-related and neurodegenerative disease
Nathan Goodyear

Friedreich's Ataxia: disease mechanisms, antioxida... [Biofactors. 2003] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...14695932

CoQ10 Vitamin E mitochondria

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  • This therapy clearly showed a rapid and sustained increase in the energy generated by the FRDA heart muscle, nearly returning to normal levels
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 and Vitamin E shown to improve mitochondrial function in clients with Friedreich's Ataxia
Nathan Goodyear

Coenzyme Q10: a review of its promise as a neuropr... [CNS Spectr. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17192765

CoQ10

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  • Experimental studies in animal models suggest that CoQ10 may protect against neuronal damage that is produced by ischemia, atherosclerosis and toxic injury.
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 and neuroprotection
Nathan Goodyear

The evidence basis for coenzyme Q therapy in oxida... [Mitochondrion. 2007] - PubMed re... - 0 views

www.ncbi.nlm.nih.gov/...17485245

CoQ10 Parkinson's cardiac disease

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  • In some mitochondrial diseases and other commoner disorders such as cardiac disease and Parkinson's disease low mitochondrial or tissue levels of CoQ10 have been demonstrated providing an obvious rationale for supplementation
  • Nathan Goodyear on 07 Feb 11
     
    Coq10 in Parkinson's disease and cardiac disease beneficial
Nathan Goodyear

Coenzyme Q10 effects in neurodegenerative disease. [Neuropsychiatr Dis Treat. 2009] - P... - 0 views

www.ncbi.nlm.nih.gov/...19966907

coenzyme q10 neurodegenerative Parkinson's Alzheimer's Huntington's ALS

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  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 shown to be beneficial in treatment of neurodegenerative diseases, Parkinson's, Alzheimer's, ALS, Huntington's, in animal models
Nathan Goodyear

Coenzyme Q10 as a possible treatment for neurodege... [Free Radic Res. 2002] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...12069110

coenzyme q10 CoQ10 Huntington's disease neurodegenerative

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  • CoQ10 can significantly extend survival, delay motor deficits and delay weight loss and attenuate the development of striatal atrophy in a transgenic mouse model of HD
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 shown to shown to slow progression of the neurodegenerative disease: Huntington's disease
Nathan Goodyear

Coenzyme Q10 administration and its potential for ... [Biofactors. 1999] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...10416039

CoQ10 neurodegenerative Alzheimer's Parkinson's ALS disease

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  • hese studies therefore raise the prospect that administration of CoQ10 may be useful for the treatment of neurodegenerative diseases.
  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 may be used to slow progression of neurodegenerative diseases such as Alzheimers, Parkinson's, ALS...
Nathan Goodyear

Oxidative stress, mitochondrial dysfunction and ce... [J Neurol Sci. 2005] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...15896810

CoQ10 mitochondria neurodegenerative disease Alzheimer's Parkinsons MS ALS oxidative stress

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  • There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Parkinson's disease, Alzheimer's disease, Friedreich's ataxia (FRDA), multiple sclerosis and amyotrophic lateral sclerosis, may involve the generation of reactive oxygen species (ROS) and/or reactive nitrogen species (RNS) associated with mitochondrial dysfunction
  • Nathan Goodyear on 07 Feb 11
     
    Mitochondrial dysfunction at heart of diseases such as Parkinson's, Alzheimers, MS, ALS..
Nathan Goodyear

Coenzyme Q treatment of neurodegenerative diseases... [Mitochondrion. 2007] - PubMed re... - 0 views

www.ncbi.nlm.nih.gov/...17485247

CoQ10 Parkinson's ALS Huntington's Alzheimer's disease

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  • Nathan Goodyear on 07 Feb 11
     
    CoQ10 shows promise in neurodegenerative disorders
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