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Nathan Goodyear

From the Cyclooxygenase-2 Inhibitor Celecoxib to a Novel Class of 3-Phosphoinositide-De... - 0 views

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    Celebrex useful in reducing colorectal polyps in individuals with familial adenomatous polyposis and in the treatment of cancer via induction of apoptosis and decrease in metastatic potential.
Nathan Goodyear

A phase II study of high-dose celecoxib and metronomic 'low-dose' cyclophosphamide and ... - 0 views

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    Oral metronomic chemotherapy with celebrex shown to provide appx 50% stable NHL disease in refractory NHL.
Nathan Goodyear

S-Adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis sympt... - 0 views

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    SAMe equivalent to celebrex for the treatment of osteoarthritis pain.
Nathan Goodyear

Cyclooxygenase-2 Induces EP1- and HER-2/Neu-Dependent Vascular Endothelial Growth Facto... - 0 views

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    COX-2 is overexpressed in a variety of human cancers i.e. colorectal, prostate, lung adenocarcinoma.  This study hightlights the increased tumor metastatic potential via upregulation of VEGF-C via EP1 and HER-2 dependent pathways.  This upregulation was correlated with survival and mets.
Nathan Goodyear

3-Phosphoinositide-Dependent Protein Kinase-1/Akt Signaling Represents a Major Cyclooxy... - 0 views

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    COX-2 therapy can inhibit tumor growth and even promote apoptosis in prostate cell model.
Nathan Goodyear

The COX-2 inhibitor celecoxib and its use in the management of prostate cancer. | Cance... - 0 views

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    COX-2 inhibition therapy useful in the treatment of prostate cancer?
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