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indiacardiacsurg

ICD Implant Procedure in India Make Your Heart Healthy - 101 Press Release - 0 views

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    Low-cost ICD implantation in India is no less than a boon for international patients, which provides them a possibility to get healed at a lower price rate than in their home country. One of the key benefits of choosing low-cost ICD implantation in India is the availability of superior quality care.
indiacardiacsurg

Innovations in Pacemaker Implantation Procedures in India - 0 views

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    ✨Top hospitals in India for pacemaker implantation offer world-class cardiac care with advanced technology, expert surgeons & affordable treatment!
indiacardiacsurg

Dr. Anil Saxena Best ICD Implantation Surgeon Fortis to Get Your Heart Healthy ~ Medic... - 0 views

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    India stands as a top destination for ICD implant procedures in India with high success rates from over 150,000 numerous cardiac strategies done each year. Dr. Anil Saxena's best ICD implantation surgeon in Fortis is known worldwide for the expert evaluation and treatment of patients with a variety of heart rhythm disorders. Phone No.: +91-9370586696 Email id: dranilsaxena@indiacardiacsurgery.com
indiacardiacsurg

Trust Dr. T. S. Kler for Life-Changing Procedure By ICD Implant Procedure in India | He... - 0 views

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    The cost of an ICD implant procedure in India is up to 50% less as compared to other developed countries, which makes India an ideal choice for this procedure. Please call +91-9370586696 or You can Mail us Email id:- drtskler@indiacardiacsurgerysite.com
indiacardiacsurg

Increased Physical Activity after Lowest Price for ICD Implantation India Linked to Les... - 0 views

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    The lowest price for ICD implantation in India is also endorsed for heart attack survivors and sufferers who've currently had percutaneous coronary intervention or passed surgical procedures. ICD treatment centers in India to increase access to cardiac and pulmonary rehabilitation programs. International Helpline Number : +91-9370586696 Email id: enquiry@indiacardiacsurgerysite.com
indiacardiacsurg

Pacemaker implation in Body By Best Pacemaker Doctor Fortis Escorts Hospital Delhi - 10... - 0 views

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    According to #DrTSKlerIndia, "The thin, bendy, lightweight device can be utilized in patients who want temporary pacing after cardiac surgical operation. "The transient electronics platform opens a new chapter in treatment and biomedical research," said the best pacemaker implantation surgeons of India. Email: drtskler@indiacardiacsurgerysite.com Phone for Appointment: +91-9370586696
indiacardiacsurg

Increased Physical Activity after Low Implantable Cardioverter-Defibrillator Price in I... - 0 views

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    Implantable cardioverter-defibrillators, additionally known as ICDs, are battery-powered gadgets positioned under the skin which could detect peculiar heart rhythms and supply an electric shock to restore a regular heartbeat. ICD procedure cost helps reduce the risk of sudden cardiac death and can be recommended for life-threatening rhythm irregularities due to myocardial infarction, cardiac arrest, or congenital heart disease. India Cardiac Surgery Hospital Helpline Number: +91-9370586696
indiacardiacsurg

Best ICD Implant Procedure Surgeon Fortis Can Change Your Life - 0 views

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    The best ICD implant procedure surgeon Fortis is a highly trained and dedicated healthcare professional specializing in heart rhythm management. Dr. Anil Saxena India has an international reputation for excellence in arrhythmia research and clinical arrhythmia management.
Nathan Goodyear

American Journal of Obstetrics & Gynecology Home Page - 0 views

  • M1 macrophages are characterized by the secretion of reactive oxygen species and proinflammatory cytokines and chemokines and can be identified via the cell surface marker CD86
  • M2 macrophages secrete growth factors and antiinflammatory immune modulators and can be identified by the cell surface marker CD206
  • an overzealous M2 response can also lead to excess tissue deposition and fibrosis
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  • Studies of similar meshes that are used in hernia repair have demonstrated that all polypropylene meshes induce a prolonged inflammatory response at the site of implantation
  • the long-term presence of activated inflammatory cells, such as macrophages at the mesh tissue interface, can impact negatively the ability of the mesh to function as intended.
  • All M1 proinflammatory and M2 proremodeling cytokines and chemokines were increased in mesh explants as compared with nonmesh tissue (Table 3Table 3), which indicated a robust, active, and ongoing host response to polypropylene long after implantation
  • Comparison of the ratio of the M2 proremodeling cytokines (IL-10+IL-4) with the M1 proinflammatory cytokines (TNF-α+IL-12p70) revealed a decrease in mesh explants as compared with controls (P = .003), which indicated a shift towards a proinflammatory profile.
  • Mesh explants contained a higher number of total cells/×200 field when compared with controls (682.46 ± 142.61 cells vs 441.63 ± 126.13 cells; P < .001) and a lower ratio of M2:M1 macrophages (0.260 ± 0.161 cells vs 1.772 ± 1.919; P = .001), which supported an ongoing proinflammatory response.
  • the host response was proportional to the amount of material in contact with the host
  • A persistent foreign body response was observed in mesh-tissue complexes that were excised from women who required surgical excision of mesh months to years after mesh implantation
  • The host response was characterized by a predominance of macrophages with an increase in both proinflammatory and proremodeling cytokines/chemokines along with increased tissue degradation, as evidenced by increased MMP-2 and -9
  • Mesh-tissue complexes removed for mesh exposure had increased pro–MMP-9 that indicated a proinflammatory and tissue destruction–type response
  • The presence of macrophages, elevated cytokines, chemokines, and MMPs in tissue-mesh complexes that were excised from patients with exposure or pain suggests that polypropylene mesh elicits an ongoing host inflammatory response
  • In the presence of a permanent foreign body, the implant is surrounded with a fibrotic capsule because it cannot be degraded
  • For hernia meshes, if the fibers are too close (<1 mm), the fibrotic response to neighboring fibers overlaps, or “bridges,” and results in “bridging fibrosis” or encapsulation of the mesh
  • Gynemesh PS has a highly unstable geometry when loaded that resulted in pore collapse and increasing stiffness of the product
  • mesh shrinkage (50-70%) has been described to occur after transvaginal insertion of prolapse meshes
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    Mesh and the abnormal immune response.
indiacardiacsurg

World's Longest Lasting ICD Makes Procedure Affordable - 0 views

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    Implantable cardioverter-defibrillators (ICDs) improve survival and are cost-effective in adults with poor left ventricular characteristics. International Helpline Number : +91-9370586696 Email id: enquiry@indiacardiacsurgerysite.com
spineneuro

New PROTI 360° Family of Implants to Enhance Spinal Fusion Surgery India - 10... - 0 views

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    About 400,000 sufferers undergo spinal fusion surgery India annually to help lessen pain and nerve root infection in India alone. During this method, a disc is eliminated and an interbody spacer is implanted to doubtlessly restore natural height between two vertebrae and create solid bone. International Helpline Number : +91-9325887033 Email Id: enquiry@spineandneurosurgeryhospitalindia.com
indiacardiacsurg

Best Pacemaker Implantation Surgeron In India - 0 views

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    Best pacemaker surgeons in India include Dr. Ajay Kaul, Dr. Z S Meharwal, Dr. Naresh Trehan, Dr. Sandeep Attawar, Dr. Devi Shetty, Dr. Ramji Mehrotra, Dr. K.S. Iyer, Dr. Y K Mishra, Dr. K R Balakrishnan, and Dr. Chandrashekhar Kulkarni,all renowned for expertise in advanced cardiac and pacemaker procedures. ❤️Trust the experts-your heartbeat deserves the best.❤️
market reports

Drug Delivery Technology Market is worth $224.2 Billion By 2017 - 0 views

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    The drug delivery technology market is segmented on the basis of route of administration into nine categories - oral, pulmonary, transdermal, injectable, ocular, nasal, topical, implantable, and transmucosal
hadiyasafdar

10 Things I wish I'd known before Breast Augmentation - 0 views

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    Breast augmentation procedure is designed to enhance the size and fullness of the breasts, usually with breast implants. If you are unhappy with the appearance of your breasts because they are smaller in size or they have lost their volume or shape due to pregnancy or rapid weight fluctuations, you might consider a breast augmentation to get the breasts of your desire.
hadiyasafdar

Is it true that Breast augmentation can cause cancer? My Experience - 0 views

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    There are many speculations associated with breast implants; they go as big as cancer and as little as scar breast augmentation. I will share with you my true experience and share my true thoughts.
hadiyasafdar

Injection Buttock Augmentation with Implants vs. Fat Injections - 0 views

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    The demand of buttock augmentation is increasing massively with the advancements in cosmetic sector. Many women who have small buttocks in comparison to their body type and frame or ones who wish to have well contoured and fuller buttocks are considering buttock augmentation. Your buttocks may have lost shape and volume over the years
Nathan Goodyear

Natural Killer Cells in Pregnancy and Recurrent Pregnancy Loss: Endocrine and Immunolog... - 0 views

  • NK cells have been the cells most extensively studied, primarily because they constitute the predominant leukocyte population present in the endometrium at the time of implantation and in early pregnancy
  • parental chromosomal abnormalities, uterine anatomic anomalies, endometrial infections, endocrine etiologies (luteal phase defect, thyroid dysfunction, uncontrolled diabetes mellitus), antiphospholipid syndrome, inherited thrombophilias, and alloimmune causes
  • estrogen
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  • progesterone
  • prolactin
  • In summary, in vivo animal experiments have shown an inhibitory role of estrogen on peripheral NK cell lytic activity, which is partly due to suppression of NK cell output by the bone marrow and partly due to suppression of individual NK cell cytotoxicity. However, in vitro studies so far have failed to show conclusively a direct effect of estrogen on NK cells.
  • At the progesterone concentrations believed to be present in the uterus [up to 10−5 m at the maternal-fetal interface (35)], studies consistently show inhibition of lymphocyte proliferation (33) and inhibition of NK cytolytic activity in vitro
  • The exact role of prolactin in NK cell regulation is unknown.
  • The overall effects of estrogen on NK cells are likely multifactorial, therefore, and depend on the type of cell affected as well as the kind of ER expressed by that cell.
  • It is known that progesterone can directly affect T cell differentiation in vitro, suppressing development of the Th1 pathway and enhancing differentiation along the Th2 pathway (44)
  • Th1 cells predominantly produce interferon-γ (IFN-γ), IL-2, and TNF-β and are involved in cell-mediated immunity. Th2 cells produce IL-4, IL-5, IL-6, IL-10, and IL-13 and stimulate humoral immunity
  • Furthermore, in response to progesterone, γδ T cells produce progesterone-induced blocking factor (PIBF) (54
  • A defining characteristic of NK cells is their ability to lyse target cells without prior sensitization and without restriction by HLA antigens.
  • NK cell function is mainly regulated by IL-2 and IFN-γ
  • IL-2 causes both NK cell proliferation and enhanced cytotoxicity. IFN-γ augments NK cytolytic activity, but does not cause NK proliferation. The two cytokines act synergistically to augment NK cytotoxicity (6).
  • The largest leukocyte population in the endometrium consists of NK cells named large granulated lymphocytes
  • there is a significant increase in the number of uNK cells throughout the secretory phase, which peaks in early pregnancy when uNK cells comprise about 75% of uterine leukocytes (62)
  • Second, uNK cell phenotype changes during the normal menstrual cycle and early pregnancy (68)
  • general proinflammatory effect of estrogen, causing an influx of macrophages and neutrophils, which is antagonized by progesterone through its receptor (70, 71).
  • The mechanism of such a progesterone-induced local immunosuppression is unclear.
  • progesterone plays an important role in proliferation and differentiation of uNK cells (32).
  • Through promotion of a uterine Th2 environment, progesterone could indirectly affect uNK cell function
  • The mechanism of this increase in uNK cell numbers has been addressed in both human and mouse models, and is likely the result of: 1) recruitment of peripheral NK cells to the uterus, and 2) proliferation of existing uNK cells
  • prolactin system plays an important role in implantation and the maintenance of pregnancy
  • the exact pathways of hormonal regulation of NK cells remain to be delineated.
  • The exact function of uNK cells has not yet been unequivocally determined
  • uNK cells express a different cytokine profile, compared with resting peripheral NK cells. mRNAs for granulocyte CSF, M-CSF, GM-CSF, TNF-α, IFN-γ, TGF-β, and leukemia inhibitory factor (LIF) have been found in decidual CD56+ cells
  • Their increased numbers in early pregnancy, their hormonal dependence, and their close proximity to the infiltrating trophoblast all suggest that they play an important role in the regulation of the maternal immune response to the fetal allograft and the control of trophoblast growth and invasion during human pregnancy
  • role of uNK cell-derived cytokines on trophoblast growth and differentiation (114, 115, 116, 117).
  • Th1 immunity to trophoblast is associated with RPL, whereas Th2 immunity is associated with a successful pregnancy
  • RPL is associated with Th1 immunity, for which NK cells are partly responsible.
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    dysregulated immune system plays role in recurrent miscarriage.  Specifically, this article discusses natural killer cells (NK).
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