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Nathan Goodyear

Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer c... - 0 views

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    Low dose vitamin C, via SVCT, increases tumor proliferation; whereas high dose decreases tumor proliferation.
Nathan Goodyear

Selenium and human health : The Lancet - 0 views

  • Low selenium status has been associated with increased risk of mortality, poor immune function, and cognitive decline
  • Higher selenium status or selenium supplementation has antiviral effects, is essential for successful male and female reproduction, and reduces the risk of autoimmune thyroid disease.
  • Prospective studies have generally shown some benefit of higher selenium status on the risk of prostate, lung, colorectal, and bladder cancers, but findings from trials have been mixed, which probably emphasises the fact that supplementation will confer benefit only if intake of a nutrient is inadequate
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    Selenium is a "U" shaped curve.  Abstract only available here.
Nathan Goodyear

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer - ScienceDirect - 0 views

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    Interesting: mouse model finds ammonia in TME inhibits T cell function.
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