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""We probably have underestimated the role our microbial flora play in modulating disease risk," says Daniel Rader, a heart disease specialist at the University of Pennsylvania School of Medicine. Rader, who was not involved in the study, says that gut bacteria may not be as big a factor in causing heart disease as diabetes or smoking, but could be important in tipping some people toward sickness. Researchers led by Stanley Hazen, a cardiologist at the Cleveland Clinic, didn't start out to study gut bacteria. In fact, says Hazen, he had "no clue - zero," that intestinal microbes were involved in heart disease. "I'd never even considered it or thought of the concept." Hazen and his colleagues compared blood plasma from healthy people to plasma from people who had had heart attacks, strokes or died to see if substances in the blood could predict who is in danger from heart disease. The researchers found 18 small molecules associated with fat buildup in the arteries. One of the best predictors turned out to be a byproduct made when gut bacteria break down a fat called choline (also known as lecithin). The more of this byproduct, called trimethylamine N-oxide or TMAO, a person or mouse has in the blood, the higher the risk of getting heart disease, the researchers found. Gut bacteria are actually middlemen in TMAO production. The microbes convert lecithin to a gas that smells like rotten fish. Then an enzyme in the liver changes the foul-smelling gas to TMAO."

"For 20 years, researchers have reported a potential link between gum disease and atherosclerotic heart disease from hardening of the arteries or stroke. "The message sent out by some in health-care professions, that heart attack and stroke are directly linked to gum disease, can distort the facts, alarm patients and perhaps shift the focus on prevention away from well-known risk factors for these diseases," said Dr. Peter Lockhart, a professor and chair of oral medicine at the Carolinas Medical Center in Charlotte, N.C. Lockhart wrote the heart group's new position statement in the journal Circulation. The statement was prepared after a three-year analysis of about 600 studies by an expert panel led by a dentist and a cardiologist."

"Middle aged and elderly people with high levels of vitamin D could reduce their chances of developing heart disease or diabetes by 43%, according to researchers at the University of Warwick."

ScienceDaily (Jan. 13, 2011) - It is becoming well accepted that, as well as too little exercise, too much sitting is bad for people's health. Now a new study has found that it is not just the length of time people spend sitting down that can make a difference, but also the number of breaks that they take while sitting at their desk or on their sofa. Plenty of breaks, even if they are as little as one minute, seem to be good for people's hearts and their waistlines.

How to improve heart health by start eating vegetarian food

"Researchers are using these Philly-made 'bioprinters' to make hearts, stomachs, BioBots makes a device that 3D-prints living cells instead of plastic."

http://www.ox.ac.uk/media/news_stories/2010/101207.html Peter Rothwell: In this new work, scientists from Oxford, Edinburgh, London and Japan used data on over 670 deaths from cancer in a range of randomised trials involving over 25,000 people. These trials compared daily use of aspirin against no aspirin and were done originally to look for any preventative effect against heart disease. The results, published in the Lancet, showed that aspirin reduced death due to any cancer by around 20% during the trials. But the benefits of aspirin only became apparent after taking the drug for 5 years or more, suggesting aspirin works by slowing or preventing the early stages of the disease so that the effect is only seen much later. After 5 years of taking aspirin, the data from patients in the trials showed that death rates were 34% less for all cancers and as much as 54% less for gastrointestinal cancers, such as oesophagus, stomach, bowel, pancreas and liver cancers.

The PROOF (Prevention of Organ Failure) Centre is a not-for-profit organization that develops and implements blood-based biomarker tests to better manage patients with heart, lung and kidney failure and prevent disease progression. By embracing a cross-disciplinary team of people and uniting organizations including commercial partners, we can speed up the development of these tests, applying them sooner to improve and save lives.

"Emily Zu-Yin Chen vom Veterans Hospital in Taipeh kürzlich auf einem Kongress der American Heart Association in Orlando berichtete. Mehr als 102.000 Krankenakten von Erwachsenen hat die Kardiologin untersucht, die bis zum Jahr 2000 keinen Schlaganfall oder Herzinfarkt gehabt hatten. Knapp die Hälfte der Teilnehmer ließ sich in den folgenden sieben Jahren mindestens einmal beim Zahnarzt den Zahnstein entfernen, die andere Hälfte nicht."

Susanna Larsson: Kaffeetrinkerinnen haben ein geringeres Risiko für Hirninfarkte http://www.wissenschaft.de/wissenschaft/news/313141.html (Jingmei Li, Karolinska Institutet, et al.: Breast Cancer Research, Bd. 13, Artikel R49) Yvonne T. van der Schouw (UMC Utrecht) et al.: Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, doi: 10.1161/ATVBAHA.109.201939 http://www.wissenschaft.de/wissenschaft/news/311350.html Helena Jernström: Kaffee senkt das Brustkrebsrisiko http://www.wissenschaft.de/wissenschaft/gutzuwissen/291553.html

"If we are putting our time and resources into communicating science but we're not on social media, we're like a tree falling in an empty forest-yes, we're making noise, but no one is listening." "Only 17% of Americans can name a living scientist. That statistic crushes my heart.""

"computerbasedmath.org is the project to perform this reset. We're building a completely new math curriculum with computer-based computation at its heart, while campaigning at all levels to redefine math education away from historical hand-calculating techniques and toward real-life problem-solving situations that drive high-concept math understanding and experience."

We belong to a remarkably quirky species. Despite our best efforts, some of our strangest foibles still defy explanation. But as science probes deeper into these eccentricities, it is becoming clear that behaviours and attributes that seem frivolous at first glance often go to the heart of what it means to be human.

ScienceDaily (Jan. 7, 2011) - Many prescriptions for the top-selling class of drugs, known as atypical antipsychotic medications, lack strong evidence that the drugs will actually help, a study by researchers at the Stanford University School of Medicine and University of Chicago has found. Yet, drugs in this class may cause such serious effects as weight gain, diabetes and heart disease, and cost Americans billions of dollars.

The supply of secure, clean, sustainable energy is arguably the most important scientific and technical challenge facing humanity in the 21st century. Rising living standards of a growing world population will cause global energy consumption to double by mid-century and triple by the end of the century. Even in light of unprecedented conservation, the additional energy needed is simply not attainable from long discussed sources these include nuclear, biomass, wind, geothermal and hydroelectric. The global appetite for energy is simply too much. Petroleum-based fuel sources (i.e., coal, oil and gas) could be increased. However, deleterious consequences resulting from external drivers of economy, the environment, and global security dictate that this energy need be met by renewable and sustainable sources. The dramatic increase in global energy need is driven by 3 billion low-energy users in the non-legacy world and by 3 billion people yet to inhabit the planet over the next half century. The capture and storage of solar energy at the individual level personalized solar energy drives inextricably towards the heart of this energy challenge by addressing the triumvirate of secure, carbon neutral and plentiful energy. This talk will place the scale of the global energy issue in perspective and then discuss how personalized energy (especially for the non-legacy world) can provide a path to a solution to the global energy challenge. Daniel G. Nocera is the Henry Dreyfus Professor of Energy at the Massachusetts Institute of Technology, Director of the Solar Revolutions Project and Director of the Eni Solar Frontiers Center at MIT. His group pioneered studies of the basic mechanisms of energy conversion in biology and chemistry. He has recently accomplished a solar fuels process that captures many of the elements of photosynthesis outside of the leaf. This discovery sets the stage for a storage mechanism for the large scale, distributed, deployment of solar energy. He has b

Together with ever-improving observations of the early universe, grand simulations are beginning to paint a single, unifying picture of why the universe looks as it does. At its heart is an almost invisible scaffold of dark matter and cold gas on which the visible constituents of the universe hang - a structure known as the cosmic web.

A new algorithm may give quantum computers a new, practical job: quickly solving monster linear equations. Such problems are at the heart of complex processes such as image and video processing, genetic analyses and even Internet traffic control.

"(PhysOrg.com) -- Did the early universe have just one spatial dimension? That's the mind-boggling concept at the heart of a theory that University at Buffalo physicist Dejan Stojkovic and colleagues proposed in 2010."

Drury, a geneticist, is a pioneer in new research exploring the biological impacts of early adversity on children. She is the first scientist to show that extreme stress in infancy can biologically age a child by shortening the tips of chromosomes, known as telomeres. These caps keep chromosomes from shrinking when cells replicate. Shorter telomeres are linked to higher risks for heart disease, cognitive decline, diabetes and mental illness in adults.