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"An accurate and colorful discription of a gout attack was elegantly written in 1683 by Dr. Thomas Sydenham who was himself a sufferer of gout: The victim goes to bed and sleeps in good health. About 2 o'clock in the morning, he is awakened by a severe pain in the great toe; more rarely in the heel, ankle or instep. This pain is like that of a dislocation, and yet the parts feel as if cold water were poured over them. Then follows chills and shiver and a little fever. The pain which at first moderate becomes more intense. With its intensity the chills and shivers increase. After a time this comes to a full height, accommodating itself to the bones and ligaments of the tarsus and metatarsus. Now it is a violent stretching and tearing of the ligaments- now it is a gnawing pain and now a pressure and tightening. So exquisite and lively meanwhile is the feeling of the part affected, that it cannot bear the weight of bedclothes nor the jar of a person walking in the room. "

The saying "You're only as old as you feel" really seems to resonate with older adults, according to research from Purdue University.

Tamir DI, Mitchell JP. Disclosing information about the self is intrinsically rewarding. Department of Psychology, Harvard University, Cambridge, MA 02138, USA. dtamir@fas.harvard.edu Abstract Humans devote 30-40% of speech output solely to informing others of their own subjective experiences. What drives this propensity for disclosure? Here, we test recent theories that individuals place high subjective value on opportunities to communicate their thoughts and feelings to others and that doing so engages neural and cognitive mechanisms associated with reward. Five studies provided support for this hypothesis. Self-disclosure was strongly associated with increased activation in brain regions that form the mesolimbic dopamine system, including the nucleus accumbens and ventral tegmental area. Moreover, individuals were willing to forgo money to disclose about the self.

Utopia Documents v2.2 is a free PDF reader that connects the static content of scientific articles to the dynamic world of online content. With a brand new look and feel that blend real-time updates with the typographic elegance of published articles, Utopia Documents brings up-to-date information directly to your desktop.

Stubborn Belly fat can make your jeans feel extra snug, many can think how to lose belly fat, but really there is something way worse about in Health2day

"We are a superficial species. And this brings me to a fascinating new paper by an all star team of psychologists, including Kurt Gray, Joshua Knobe, Mark Sheskin, Paul Bloom and Lisa Feldman Barrett.. we automatically assume that the capacity to think and the capacity to feel are in opposition. It's a zero sum game. What does all this have to do with nakedness? The psychologists demonstrated it's quite easy to shift our perceptions of other people from having a mind full of agency to having a mind interested in experience: all they have to do is take off their clothes."

"45% of Japanese women aged 16-24 are 'not interested in or despise sexual contact'. More than a quarter of men feel the same wa"

"Today, the White House honored twelve people across the country that they considered to be "Champions Of Change" in Citizen Science. I was one of the twelve who were nominated and then selected. I do feel quite honored. I was asked to write a few words on my thoughts about citizen science for the White House blog - here's what I had to say."

"Note that the antimicrobial peptides are produced largely in the fat bodies-so there would be less of this sort of response in forager bees, which don't maintain their fat bodies. This makes sense, since foragers aren't expected to live for long. However, keep in mind that the bees in protein-hungry colonies are unable to develop their fat bodies fully-this one point where nutrition ties in to immunity. Surprisingly, Jay Evans found that these genes are not upregulated in bees from CCD colonies, even though the bees are full of pathogens! There are a few potential explanations for this finding that come to mind: The bee hemocytes are not recognizing the pathogens as foreign (suppression of recognition systems, perhaps by viruses?). The colonies could be protein-starved. Something is suppressing the transcription of the genes, or their translation to peptides. Note that viruses can do this very thing, which I feel may be a big clue!"

"Darkness can conceal identity and encourage moral transgressions; thus Ralph Waldo Emerson wrote in "Worship" in The Conduct of Life (1860), "as gaslight is the best nocturnal police, so the universe protects itself by pitiless publicity." New research in Psychological Science, a journal of the Association for Psychological Science, shows that darkness may also induce a psychological feeling of illusory anonymity, just as children playing "hide and seek" will close their eyes and believe that other cannot see them, the experience of darkness, even one as subtle as wearing a pair of sunglasses, triggers the belief that we are warded from others' attention and inspections."

Home-school mom Susan Mule wishes she hadn't taken a friend's advice and tried a textbook from a popular Christian publisher for her 10-year-old's biology lessons. Mule's precocious daughter Elizabeth excels at science and has been studying tarantulas since she was 5. But she watched Elizabeth's excitement turn to confusion when they reached the evolution section of the book from Apologia Educational Ministries, which disputed Charles Darwin's theory. "I thought she was going to have a coronary," Mule said of her daughter, who is now 16 and taking college courses in Houston. "She's like, 'This is not true!'"

Home Fooling.

For theoretical neurobiologist and author Mark Changizi, "why" has always been more interesting than "how." While many scientists focus on the mechanics of how we do what we do, his research aims to grasp the ultimate foundations underlying why we think, feel and see as we do. Guided by this philosophy, he has made important discoveries on why we see in color, why we see illusions, why we have forward-facing eyes, why letters are shaped as they are, why the brain is organized as it is, why animals have as many limbs and fingers as they do, and why the dictionary is organized as it is.

The fruit fly has evolved a method for arranging the tiny, hair-like structures it uses to feel and hear the world that's so efficient a team of scientists in Israel and at Carnegie Mellon University says it could be used to more effectively deploy wireless sensor networks and other distributed computing applications.

Music, an abstract stimulus, can arouse feelings of euphoria and craving, similar to tangible rewards that involve the striatal dopaminergic system. Using the neurochemical specificity of [11C]raclopride positron emission tomography scanning, combined with psychophysiological measures of autonomic nervous system activity, we found endogenous dopamine release in the striatum at peak emotional arousal during music listening. To examine the time course of dopamine release, we used functional magnetic resonance imaging with the same stimuli and listeners, and found a functional dissociation: the caudate was more involved during the anticipation and the nucleus accumbens was more involved during the experience of peak emotional responses to music. These results indicate that intense pleasure in response to music can lead to dopamine release in the striatal system. Notably, the anticipation of an abstract reward can result in dopamine release in an anatomical pathway distinct from that associated with the peak pleasure itself. Our results help to explain why music is of such high value across all human societies.

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In what may feel like a flashback to the porn wars of the '60s, a new study investigates the link between a country's relative gender equality and the degree of female "empowerment" in the X-rated entertainment it consumes. Researchers at the University of Hawaii focused on three countries in particular: Norway, the United States and Japan, which are respectively ranked 1st, 15th and (yikes) 54th on the United Nations' Gender Empowerment Measure (GEM). To simplify their analysis, their library of smut was limited to explicit photographs of women "from mainstream pornographic magazines and Internet websites, as well as from the portfolios of the most popular porn stars from each nation." Then they set out to evaluate each image on both a disempowerment and an empowerment scale, using respective measures like whether the woman is "bound and dominated" by "leashes, collars, gags, or handcuffs" or "whether she has a natural looking body." Their hypothesis was that societies with greater gender equity will consume pornography that has more representations of "empowered women" and less of "disempowered women." It turned out the former was true, but, contradictory as it may sound, the latter was not. "While Norwegian pornography offers a wider variety of body types -- conforming less to a societal ideal that is disempowering to the average woman -- there are still many images that do not promote a healthy respect for women," the researchers explain. In other words, Norwegian porn showed more signs of female empowerment, but X-rated images in all three countries equally depicted women in demeaning positions and scenarios. This, the researchers surmise, "suggests that empowerment and disempowerment within pornography are potentially different constructs." So, gender equality is accompanied by sexual interest in a broader range of beauty types but not a decrease in porn's infantilization of females, use of dominating fetish gear on women or any of the other characteristics th

What is cancer? Everyone knows that it is a terrifying disease and has some ideas about a mass of cells that grow uncontrollably but I get the feeling that many people don't quite understand how it actually happens.

Brain, bodily awareness, and the emergence of a conscious self: these entities and their relations are explored by Germanphilosopher and cognitive scientist Metzinger. Extensively working with neuroscientists he has come to the conclusion that, in fact, there is no such thing as a "self" -- that a "self" is simply the content of a model created by our brain - part of a virtual reality we create for ourselves. But if the self is not "real," he asks, why and how did it evolve? How does the brain construct the self? In a series of fascinating virtual reality experiments, Metzinger and his colleagues have attempted to create so-called "out-of-body experiences" in the lab, in order to explore these questions. As a philosopher, he offers a discussion of many of the latest results in robotics, neuroscience, dream and meditation research, and argues that the brain is much more powerful than we have ever imagined. He shows us, for example, that we now have the first machines that have developed an inner image of their own body -- and actually use this model to create intelligent behavior. In addition, studies exploring the connections between phantom limbs and the brain have shown us that even people born without arms or legs sometimes experience a sensation that they do in fact have limbs that are not there. Experiments like the "rubber-hand illusion" demonstrate how we can experience a fake hand as part of our self and even feel a sensation of touch on the phantom hand form the basis and testing ground for the idea that what we have called the "self" in the past is just the content of a transparent self-model in our brains. Now, as new ways of manipulating the conscious mind-brain appear on the scene, it will soon become possible to alter our subjective reality in an unprecedented manner. The cultural consequences of this, Metzinger claims, may be immense: we will need a new approach to ethics, and we will be forced to think about ourselves in a fundamentally new way. At

The studies found:People who perceive their car as a reflection of their self-identity are more likely to behave aggressively on the road and break the law.People with compulsive tendencies are more likely to drive aggressively with disregard for potential consequences.Increased materialism, or the importance of one's possessions, is linked to increased aggressive driving tendencies.Young people who are in the early stages of forming their self-identity might feel the need to show off their car and driving skills more than others. They may also be overconfident and underestimate the risks involved in reckless driving.Those who admit to aggressive driving also admit to engaging in more incidents of breaking the law.A sense of being under time and pressure leads to more aggressive driving.