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The seminar begins with an examination of the fundamental vocabulary and concepts related to metrology. Topics include: accuracy, precision, calibration, and "uncertainty ratios". Several of the standard methods for analyzing measurement variation are then described and explained, as derived from AIAG's Measurement System Analysis reference book. The methods include: Gage R&R (ANOVA method, for 3 gages, 3 persons, 3 replicates, and 10 parts), Gage Correlation (for 3 gages), Gage Linearity, and Gage Bias. The seminar ends with an explanation of how to combine all relevant uncertainty information into an "Uncertainty Budget" that helps determine the appropriate width of QC specification intervals (i.e., "guard-banded specifications"). Spreadsheets are used to demonstrate how to perform the methods described during the seminar.

"Tatsächlich zeigte sich der Wirkstoff im Praxistest mit fettleibigen Mäusen als äußerst effektiv: Innerhalb von nur einer Woche reduzierten die mit Celastrol behandelten Mäuse ihre Nahrungsaufnahme um etwa 80 Prozent im Vergleich zu den nicht therapierten. Am Ende der dritten Woche hatten die behandelten Tiere im Schnitt 45 Prozent ihres ursprünglichen Körpergewichts verloren - und zwar fast ausschließlich durch die Verbrennung von Fettreserven."

A new study in The Lancet rates the harmfulness of 20 psychoactive drugs according to 16 criteria and finds that alcohol comes out on top. Although that conclusion is generating headlines, it is not at all surprising, since alcohol is, by several important measures (including acute toxicity, impairment of driving ability, and the long-term health effects of heavy use), the most dangerous widely used intoxicant, and its abuse is also associated with violence, family breakdown, and social estrangement. A group of British drug experts gathered by the Independent Scientific Committee on Drugs (ISCD) rated alcohol higher than most or all of the other drugs for health damage, mortality, impairment of mental functioning, accidental injury, economic cost, loss of relationships, and negative impact on community. Over all, alcohol rated 72 points on a 100-point scale, compared to 55 for heroin, 54 for crack cocaine, and 33 for methamphetamine. Cannabis got a middling score of 20, while MDMA (Ecstasy), LSD, and psilocybin mushrooms were at the low end, with ratings of 9, 7, and 6, respectively.

For whatever reason, from whatever strange motive, scientists have speculated on the question of how our universe will end. It matters not to them that this denouement exists so far into the future that the numbers are incomprehensible in any meaningful way. They simply want to know. They surmise that the universe will end either in a big crunch or a big freeze.

Is warfare really an immutable part of our nature, or is it something we can overcome? Some researchers now suspect the latter

In the first clinical proof of its kind, a drug has dramatically shrunk cancerous tumors by disrupting a key genetic pathway. But a study targeting one deadly brain cancer, medulloblastoma, ended in disappointment as the patient's once-tamed tumor quickly developed resistance to the drug and killed him.

Whether used to clinch a guilty verdict or predict the end of a "CSI" episode, DNA evidence has given millions of people a sense of certainty -- but the outcomes of using DNA evidence have often been far from certain, according to David Kaye, Distinguished Professor of Law at Penn State.

It's not quite Cyclops, the sci-fi superhero from the X-Men franchise whose eyes produce destructive blasts of light, but for the first time a laser has been created using a biological cell. The human kidney cell that was used to make the laser survived the experience. In future such "living lasers" might be created inside live animals, which could potentially allow internal tissues to be imaged in unprecedented detail. It's not the first unconventional laser. Other attempts include lasers made of Jell-O and powered by nuclear reactors (see box below). But how do you go about giving a living cell this bizarre ability? Typically, a laser consists of two mirrors on either side of a gain medium - a material whose structural properties allow it to amplify light. A source of energy such as a flash tube or electrical discharge excites the atoms in the gain medium, releasing photons. Normally, these would shoot out in random directions, as in the broad beam of a flashlight, but a laser uses mirrors on either end of the gain medium to create a directed beam. As photons bounce back and forth between the mirrors, repeatedly passing through the gain medium, they stimulate other atoms to release photons of exactly the same wavelength, phase and direction. Eventually, a concentrated single-frequency beam of light erupts through one of the mirrors as laser light.

The supply of secure, clean, sustainable energy is arguably the most important scientific and technical challenge facing humanity in the 21st century. Rising living standards of a growing world population will cause global energy consumption to double by mid-century and triple by the end of the century. Even in light of unprecedented conservation, the additional energy needed is simply not attainable from long discussed sources these include nuclear, biomass, wind, geothermal and hydroelectric. The global appetite for energy is simply too much. Petroleum-based fuel sources (i.e., coal, oil and gas) could be increased. However, deleterious consequences resulting from external drivers of economy, the environment, and global security dictate that this energy need be met by renewable and sustainable sources. The dramatic increase in global energy need is driven by 3 billion low-energy users in the non-legacy world and by 3 billion people yet to inhabit the planet over the next half century. The capture and storage of solar energy at the individual level personalized solar energy drives inextricably towards the heart of this energy challenge by addressing the triumvirate of secure, carbon neutral and plentiful energy. This talk will place the scale of the global energy issue in perspective and then discuss how personalized energy (especially for the non-legacy world) can provide a path to a solution to the global energy challenge. Daniel G. Nocera is the Henry Dreyfus Professor of Energy at the Massachusetts Institute of Technology, Director of the Solar Revolutions Project and Director of the Eni Solar Frontiers Center at MIT. His group pioneered studies of the basic mechanisms of energy conversion in biology and chemistry. He has recently accomplished a solar fuels process that captures many of the elements of photosynthesis outside of the leaf. This discovery sets the stage for a storage mechanism for the large scale, distributed, deployment of solar energy. He has b

Telomeres are necessary for several reasons, among them to act as 'padding' during cell duplication. Every time a linear DNA molecule is replicated it loses a few base pairs from the ends (the reason why is quite interesting,

Telomeres are necessary for several reasons, among them to act as 'padding' during cell duplication. Every time a linear DNA molecule is replicated it loses a few base pairs from the ends (the reason why is quite interesting,

Genetic research permits the genetic diagnosis of susceptibilities of hereditary diseases. We know that the close members of a family may share many of their genes. By linking to a family in genetic research, scientists can study which genetic variances are shared by the family members who have the disease but not found in the rest of the family.

"The Decentralized Library of Alexandria is an open-source standard in active development to allow users to publish and distribute original content themselves, from music to videos to feature films, 3d printable inventions, recipes, books and just about anything else. It is a unified, ever-growing library of art, history and culture which users interact with through a variety of front end apps. A native browser is in continuing development, but the Alexandria standard can also be used by other open source developers and even current industry incumbents like YouTube, Soundcloud, iTunes and Netflix to offer a far superior value proposition to content providers and a better experience for users than currently available."

When you are unfilled handed and required to pay off your unanticipated monetary expenses at the end of the month, you should believe applying with saving account payday loans without think too much. These financial services are a correct choice of monetary arrangement that present speedy finances at the toughest fiscal phase without any trouble.

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ScienceDaily (June 9, 2011) - Air and water meet over most of Earth's surface, but exactly where one ends and the other begins turns out to be a surprisingly subtle question.

Oil prices have edged up as the Organization of the Petroleum Exporting Countries (OPEC) and its partners are set to extend output cuts until at least the end of 2019 at their meeting in Vienna.

"Our mission at YC is to enable as much innovation as we can. Mostly this means funding startups. But startups aren't ideal for some kinds of innovation-for example, work that requires a very long time horizon, seeks to answer very open-ended questions, or develops technology that shouldn't be owned by any one company."

Do you know a video is predicted to account for more than 70% of all internet traffic by the end of 2017.

Over 300 million tons of Plastic produce every year but only 10% are recycled. More than 8 million tons of plastic ends up in our ocean. Dow finds a new way to prevent plastic pollution from polluting our oceans to turn hard plastic into a more durable and longer-lasting road, called Plastic roads.