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Erich Feldmeier

J. Lee, Vincent Harley: The male fight-flight response: MAO-A, A result of SRY regulati... - 0 views

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    "Males and females differ in their biobehavioural response to stress, where males exhibit a heightened sympathetic response to stress compared with females. Specifically, Taylor et al. 1 propose that the classic "fight-or-flight" response to stress is adaptive for males, whilst females engage in a so-called "tend-and-befriend" response to stress. We propose that the Y-chromosome gene, SRY (sex-determining region on the Y chromosome), provides a genetic basis for the heightened sympathetic reactivity to stress and thus predominance of "fight-flight" response in males. Our idea is based on studies that demonstrate (i) the presence of SRY in brain regions and peripheral tissues abundant in catecholamines, (ii) the regulation of catecholamine synthesis and breakdown by SRY, and (iii) the role of SRY in voluntary movement and blood pressure in males"
Erich Feldmeier

Zen Faulkes: NeuroDojo: A patent clerk's pay, or, why is science so expensive? - 0 views

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    "We often think that the limiting factors to doing science are intellectual or technological. There are many unsolved scientific problems that we know how to answer. We aren't waiting for any conceptual breakthroughs or new technologies. We're waiting for people. We need "hands at the bench" to put in the time to collect the data. The instabilities of salary is a major limiting factor for science and is probably a big reason a lot of them get out of science: they don't see a way to pay the bills. Creating permanent, stable positions for scientists would release a lot of scientific research."
Erich Feldmeier

Michael Nielsen: Reinventing Discovery | Michael Nielsen - 0 views

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    The book is about networked science: the use of online tools to transform the way science is done. In the book I make the case that networked science has the potential to dramatically speed up the rate of scientific discovery, not just in one field, but across all of science. Furthermore, it won't just speed up discovery, but will actually amplify our collective intelligence, expanding the range of scientific problems which can be attacked at all. But, as I explain in the book, there are cultural obstacles that are blocking networked science from achieving its full potential. And so the book is also a manifesto, arguing that networked science must be open science if it is to realize its potential. Making the change to open science is a big challenge. In my opinion it's one of the biggest challenges our society faces, one that requires action on many fronts. One of those fronts is to make sure that everyone - including scientists, but also grant agencies, governments, libraries, and, especially, the general public -- understands how important the stakes are, and how urgent is the need for change.
Erich Feldmeier

Holger Sondermann: biofilms - 0 views

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    "Bacterial signaling controlling biofilm formation and pathogenicity Opportunistic bacterial pathogens cause a variety of infectious diseases. Their ability to sense and respond to different microenvironments, particularly during the transition from a free-living to an indwelling pathogenic lifestyle, is largely dependent on a variety of adaptational strategies (Hall-Stoodley et al., 2004). Examples include phenotypic variation, biofilm formation, resistance to antibiotic treatments and virulence gene expression, suggested to be interlinked phenotypes largely dependent on bacterial signaling and changes in their transcription profiles "
Erich Feldmeier

Agustin Fuentes: Get Over It: Men and Women Are from the Same Planet | Guest Blog, Scie... - 0 views

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    "However, anthropological datasets show enormous complexity in how and why men and women behave the ways that they do [vi]. Studies in human biology and anthropology regularly demonstrate a dynamic flexibility and complex biocultural context for all human behavior, and this is especially true for gender.... No matter how much some want it to be true, it is just not that simple; there are no clear cut and easy answers to why we do what we do, and why men and women sometimes have problems getting along. To ignore the enormous wealth of data on how men and women are similar AND different and to try to tackle this enormously complex reality via one-dimensional approaches is just poor science."
Janos Haits

YaCy 'KIT-sn-head': About - 0 views

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    Sciencenet - Towards a global search and share engine for all scientific knowledge. We have developed a prototype distributed scientific search engine technology, "Sciencenet", which facilitates rapid searching over this large data space. By "bringing the search engine to the data" we do not require server farms. This platform also allows users to contribute to the search index and publish their large scale data to support e-Science. Furthermore, a community-driven method guarantees that only scientific content is crawled and presented. Our peer-to-peer approach is sufficiently scalable for the science web without performance or capacity tradeoff.
Janos Haits

AskMe - Experiment Publisher - 0 views

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    AskMe - Experiment Publisher is a simple to use software package for users to publish their large scale life science experiment data on to the web by use of data mining and visualization concepts. With use of AskMe, scientists can share these datasets easily with their collaborators or they can be made publicly accessible to the scientific community by Sciencenet - our distributed peer to peer search and share engine.
Erich Feldmeier

How to break into science writing using your blog and social media (#sci4hels) | The SA... - 0 views

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    "It is important to be aware that 20th century media ecosystem is a very unusual aberration in the way people communicated throughout history. Means of production were expensive. Very few people could afford to own printing presses, radio and TV studios, etc. Running all that complicated equipment required technical expertise and professional training. Thus media became locked up in silos, hierarchical, broadcast-only with little-to-none (and then again centrally controlled) means for feedback. There was a wealthy, vocal minority that determined what was news, and how to frame it, and the vast majority was consuming the news in silence"
Erich Feldmeier

Robin Mellors-Bourne: #Vitae #STEM Researchers' 'unrealistic' hopes of academic careers... - 0 views

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    "There is a "significant credibility gap" between researchers' expectations and the likelihood of their forging long-term careers in higher education, a survey has found. More than three-quarters of research staff responding to the Careers in Research Online Survey 2013 said they aspired to a career in higher education and around two-thirds said they expected to achieve this. But it was "unrealistic to expect" that this number of research staff, or even half of those in the early stages of their career, would be able to secure a long-term research role in higher education, says the report, based on the survey produced by Vitae, the careers organisation for researchers."
Erich Feldmeier

@biogarage Sick Bees - Part 3: The Bee Immune System @ Scientific Beekeeping - 0 views

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    "Note that the antimicrobial peptides are produced largely in the fat bodies-so there would be less of this sort of response in forager bees, which don't maintain their fat bodies. This makes sense, since foragers aren't expected to live for long. However, keep in mind that the bees in protein-hungry colonies are unable to develop their fat bodies fully-this one point where nutrition ties in to immunity. Surprisingly, Jay Evans found that these genes are not upregulated in bees from CCD colonies, even though the bees are full of pathogens! There are a few potential explanations for this finding that come to mind: The bee hemocytes are not recognizing the pathogens as foreign (suppression of recognition systems, perhaps by viruses?). The colonies could be protein-starved. Something is suppressing the transcription of the genes, or their translation to peptides. Note that viruses can do this very thing, which I feel may be a big clue!"
Charles Daney

From butterfly to caterpillar: How children grow up - New Scientist - 0 views

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    In the past 30 years, a scientific revolution has completely transformed our understanding of babies and young children. Babies both know more and learn more than we would ever have thought possible, and we have recently begun to grasp the mechanisms by which they do this. I wrote The Philosophical Baby to try to show that thinking about childhood can help us answer deep questions about truth, imagination, love, consciousness, identity and morality. Without exaggeration, I believe it can tell us how we came to be human.
Skeptical Debunker

Acupuncture lessens depression symptoms during pregnancy, study shows - 0 views

  • The study authors, led by Rachel Manber, PhD, professor of psychiatry and behavioral sciences, said they hope the results will raise awareness of the problem of depression during pregnancy and provide patients and physicians an alternative to antidepressants. "This standardized acupuncture protocol could be a viable treatment option for depression during pregnancy," they wrote in a paper that will appear in the March issue of Obstetrics & Gynecology. Up to 14 percent of pregnant women may have major depressive disorder, a condition characterized by feelings of dread, gloom and hopelessness, and a loss of interest in normally pleasurable activities. Some women suffer from depression before becoming pregnant, stop taking their medication and then experience a relapse; in other women, pregnancy itself may cause depression.
  • For this study, the researchers recruited 150 women whose pregnancies were between 12 and 30 weeks gestation and who met the criteria for major depressive disorder. The women were randomized to receive one of three treatments: acupuncture specific for depression; control acupuncture, during which needles were inserted in points not known to help alleviate depressive symptoms; or massage. All of the women received eight weeks of therapy and were assessed for depression at the four- and eight-week marks by an interviewer who was unaware of the treatment each woman received. The researchers found that women who received the depression-specific acupuncture experienced a bigger reduction in depression symptoms than the women in the other groups. The response rate — defined as having a 50 percent or greater reduction in symptoms — was 63 percent for the women receiving depression-specific acupuncture, compared with 44 percent for the women in the other two treatment groups combined. The researchers weren't surprised by what they found — a pilot study yielded similar results, and other studies have shown acupuncture is an effective treatment for depression in the general public — but they were pleased with the results. "I don't think that one-size-fits-all treatments are appropriate for everyone, but acupuncture should be considered as an option," said Lyell. "I hope that people will respect the rigorous methodology used in this blinded, randomized, controlled trial and accept the result: Traditional acupuncture was associated with a significant improvement in depression."
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    Acupuncture appears to be an effective way to reduce depression symptoms during pregnancy, according to a first-of-its-kind study from Stanford University School of Medicine researchers.
Skeptical Debunker

Giant Snake Ate Baby Dinosaurs | LiveScience - 0 views

  • The site that yielded the snake — dubbed Sanajeh indicus, or "ancient-gaped one from India" — was located near a village in Gujarat in western India. It was a rich nesting ground for sauropods known as titanosaurs, with evidence for hundreds of egg clutches, each containing about six to 12 round, spherical eggs. Two other instances of fossil snakes found with these clutches suggest the newly described serpent species made its living plundering nests for young dinosaurs. "It would have been a smorgasbord," said researcher Jason Head, a paleontologist at the University of Toronto at Mississauga. "Hundreds or thousands of defenseless baby sauropods could have supported an ecosystem of predators during the hatching season." The dinosaur eggs likely were laid along the sandy banks of a small, quiet tributary and covered afterward by the mother with a thin layer of sediment. These dinosaurs did not seem to look after their young — no evidence for adults has been found at the site. The fact the bones and delicate structures, such as eggshells and the snake's skull, are arranged in anatomical order (as they would appear in real life) points to quick entombment of a serpent caught in the act, as opposed to them all getting washed together after they died. "Burial was rapid and deep," said researcher Shanan Peters, a geologist at the University of Wisconsin. "Probably a pulse of slushy sand and mud released during a storm."
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    The last thing hatchling dinosaurs might have seen were giant snakes, researchers say. Scientists found the nearly complete remains of an 11-foot-long, 67-million-year-old serpent coiled around a crushed dinosaur egg right next to a hatchling in the nest of a sauropod dinosaur, the largest animals to have ever walked the Earth. "We think that the hatchling had just exited its egg, and that activity attracted the snake," explained researcher Dhananjay Mohabey, a paleontologist at the Geological Survey of India. "It was such a thrill to discover such a portentous moment frozen in time."
Skeptical Debunker

Does promiscuity prevent extinction? - 0 views

  • Known as 'polyandry' among scientists, the phenomenon of females having multiple mates is shared across most animal species, from insects to mammals. This study suggests that polyandry reduces the risk of populations becoming extinct because of all-female broods being born. This can sometimes occur as a result of a sex-ratio distortion (SR) chromosome, which results in all of the Y chromosome 'male' sperm being killed before fertilisation. The all-female offspring will carry the SR chromosome, which will be passed on to their sons in turn resulting in more all-female broods. Eventually there will be no males and the population will die out. For this study, the scientists worked with the fruitfly Drosophila pseudoobscura. They gave some populations the opportunity to mate naturally, meaning that the females had multiple partners. The others were restricted to having one mate each. They bred several generations of these populations, so they could see how each fared over time. Over fifteen generations, five of the twelve populations that had been monogamous became extinct as a result of males dying out. The SR chromosome was far less prevalent in the populations in which females had the opportunity to have multiple mates and none of these populations became extinct. The study shows how having multiple mates can suppress the spread of the SR chromosome, making all-female broods a rarity. This is because males that carry the SR chromosome produce only half as many sperm as normal males. When a female mates with multiple males, their sperm will compete to fertilise her eggs. The few sperm produced by males carrying the SR chromosome are out-competed by the sperm from normal males, and the SR chromosome cannot spread.
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    Promiscuous females may be the key to a species' survival, according to new research by the Universities of Exeter and Liverpool. Published today (25 February) in Current Biology, the study could solve the mystery of why females of most species have multiple mates, despite this being more risky for the individual.
Skeptical Debunker

GPS Jamming Devices Pose Many Threats (w/ Video) - 0 views

  • GPS jammers send out a radio signal that’s the same frequency as the satellite signal. Since GPS satellite signals are weak, a GPS jamming device that puts out approximately 2 watts is sufficient to disrupt a GPS signal in a vehicle that’s approximately within 10 feet of the device. This leaves the in-vehicle system unable to establish its position and report back to a GPS tracking center, where the vehicle is registered. There are also fears that terrorists can use these devices to disrupt air traffic and cause severe safety and economic damage to the US. More powerful jammers could disrupt GPS signals in close proximity of airports, causing safety concerns. Our military overseas use GPS extensively to record their position as well as the position of the enemy. With GPS jamming devices in the hands of our enemy, U.S. and allied forces can be severely impacted when launching ground and air-strikes.
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    The latest GPS jamming devices are now being used by car thieves in the UK to render stolen cars and trucks undetectable by law enforcement. These devices also pose a threat to airlines and US military overseas.
Skeptical Debunker

Traces of the past: Computer algorithm able to 'read' memories - 0 views

  • To explore how such memories are recorded, the researchers showed ten volunteers three short films and asked them to memorise what they saw. The films were very simple, sharing a number of similar features - all included a woman carrying out an everyday task in a typical urban street, and each film was the same length, seven seconds long. For example, one film showed a woman drinking coffee from a paper cup in the street before discarding the cup in a litter bin; another film showed a (different) woman posting a letter. The volunteers were then asked to recall each of the films in turn whilst inside an fMRI scanner, which records brain activity by measuring changes in blood flow within the brain. A computer algorithm then studied the patterns and had to identify which film the volunteer was recalling purely by looking at the pattern of their brain activity. The results are published in the journal Current Biology. "The algorithm was able to predict correctly which of the three films the volunteer was recalling significantly above what would be expected by chance," explains Martin Chadwick, lead author of the study. "This suggests that our memories are recorded in a regular pattern." Although a whole network of brain areas support memory, the researchers focused their study on the medial temporal lobe, an area deep within the brain believed to be most heavily involved in episodic memory. It includes the hippocampus - an area which Professor Maguire and colleagues have studied extensively in the past. They found that the key areas involved in recording the memories were the hippocampus and its immediate neighbours. However, the computer algorithm performed best when analysing activity in the hippocampus itself, suggesting that this is the most important region for recording episodic memories. In particular, three areas of the hippocampus - the rear right and the front left and front right areas - seemed to be involved consistently across all participants. The rear right area had been implicated in the earlier study, further enforcing the idea that this is where spatial information is recorded. However, it is still not clear what role the front two regions play.
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    Computer programs have been able to predict which of three short films a person is thinking about, just by looking at their brain activity. The research, conducted by scientists at the Wellcome Trust Centre for Neuroimaging at UCL (University College London), provides further insight into how our memories are recorded.
thinkahol *

Nuclear radiation affects sex of babies, study suggests - 0 views

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    ScienceDaily (May 27, 2011) - Ionizing radiation is not without danger to human populations. Indeed, exposure to nuclear radiation leads to an increase in male births relative to female births, according to a new study by Hagen Scherb and Kristina Voigt from the Helmholtz Zentrum München.
thinkahol *

First 'living' laser made from kidney cell - physics-math - 12 June 2011 - New Scientist - 0 views

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    It's not quite Cyclops, the sci-fi superhero from the X-Men franchise whose eyes produce destructive blasts of light, but for the first time a laser has been created using a biological cell. The human kidney cell that was used to make the laser survived the experience. In future such "living lasers" might be created inside live animals, which could potentially allow internal tissues to be imaged in unprecedented detail. It's not the first unconventional laser. Other attempts include lasers made of Jell-O and powered by nuclear reactors (see box below). But how do you go about giving a living cell this bizarre ability? Typically, a laser consists of two mirrors on either side of a gain medium - a material whose structural properties allow it to amplify light. A source of energy such as a flash tube or electrical discharge excites the atoms in the gain medium, releasing photons. Normally, these would shoot out in random directions, as in the broad beam of a flashlight, but a laser uses mirrors on either end of the gain medium to create a directed beam. As photons bounce back and forth between the mirrors, repeatedly passing through the gain medium, they stimulate other atoms to release photons of exactly the same wavelength, phase and direction. Eventually, a concentrated single-frequency beam of light erupts through one of the mirrors as laser light.
Walid Damouny

Studies suggest males have more personality - 0 views

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    "Males have more pronounced personalities than females across a range of species - from humans to house sparrows - according to new research. Consistent personality traits, such as aggression and daring, are also more important to females when looking for a mate than they are to males. Research from the University of Exeter draws together a range of studies to reveal the role that sexual selection plays in this disparity between males and females."
anonymous

Learn More About Dairy Farming - 1 views

There is so much about dairy farming that is not known by the common public. With the majority of people going back to organic farming and natural products, this kind of dairy products has a lot of...

organic farming dairy Mahendra The Effect science research trivedi

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