PHE - Resources

DeAunne Denmark MD, PhD; Very interesting developments. Really hope this will start pointing toward more effective, targeted treatments. "Evidence is growing that self-attacking 'autoantibodies' could be the key to understanding some of the worst cases of SARS-CoV-2 infection."

Interesting email thread, initiated by Mike, with additional resources suggested by DeAunne

Everyone ages at different rates. Our "true age" (also called "biological age") depends on how much inflammation we encounter in our lifestyle and environment, combining with our genetics. True age represents our capacity for resilience, in tolerating and recovering from these life stresses. By increasing this resilience, we could even get younger in true age! It requires frequent tracking of biomarkers like heart rate variability (HRV).

"The national map below displays those locations that have received shipments of monoclonal antibody therapeutics under the U.S. Food and Drug Administration Emergency Use Authorization (EUA) authority, within the past several weeks. "

Recommended by: DeAunne Denmark, MD, PhD "It's important for the public to be aware of what's available to them in the world of genomics and precision medicine. Various resources are available that provide general and disease-specific information about genomics and precision medicine. A list of some resources available to the public is provided below, but additional resources are likely available through your health provider or other groups such as the US National Institutes of Health."

The resource index in this article is incredible.

DeAunne Denmark, MD, PhD: This is a good summary of current state re: clinical application of digital health technologies w/ one of the top academics in precision med - Geoff Ginsburg at Duke Ctr for Applied Genomics & PM. "Interview with Geoffrey S. Ginsburg, MD, PhD, author of Digital Health-The Need to Assess Benefits, Risks, and Value"

"Follow this page to share information that can benefit someone you know. The U.S. Department of Health and Human Services (HHS) touches the lives of nearly all Americans from research to food safety, health care, aging and much more."

"Follow this page to share information that can benefit someone you know. The U.S. Department of Health and Human Services (HHS) touches the lives of nearly all Americans from research to food safety, health care, aging and much more."

"Follow this page to share information that can benefit someone you know. The U.S. Department of Health and Human Services (HHS) touches the lives of nearly all Americans from research to food safety, health care, aging and much more."

"Follow this page to share information that can benefit someone you know. The U.S. Department of Health and Human Services (HHS) touches the lives of nearly all Americans from research to food safety, health care, aging and much more."

Mike Kurisu: This is an online symposia from my alma mater medical school. I was one of original founders a long time ago. I am not speaking this year but know all the speakers. I have registered and will get access to recordings and have Dennis post them all for you to view at your leisure.

Recommended by Sharon Wampler This is my good friend Beth Baber's company. Maybe potential synergy with PHE/Apollo http://www.tigohealth.com/ Tyler - you may know Beth, she started TNCI (The Nicolas Conner Institute). She was a cancer researcher at TSRI and her husband is faculty there

Contributed by Tyler Orion

Mike Kurisu: "a good overview of the science as we know it now..."

"The company, which received about $30 million from the National Institutes of Health to ramp up production capacity, will be able to produce about 100,000 tests a day by January, Parsons says. By March, production should increase to about 250,000 tests a day. By June, productions should hit 1 million a day."

"Abstract Elevated core temperature constitutes an important biomarker for COVID-19 infection; however, no standards currently exist to monitor fever using wearable peripheral temperature sensors. Evidence that sensors could be used to develop fever monitoring capabilities would enable large-scale health-monitoring research and provide high-temporal resolution data on fever responses across heterogeneous populations. We launched the TemPredict study in March of 2020 to capture continuous physiological data, including peripheral temperature, from a commercially available wearable device during the novel coronavirus pandemic. We coupled these data with symptom reports and COVID-19 diagnosis data. Here we report findings from the first 50 subjects who reported COVID-19 infections. These cases provide the first evidence that illness-associated elevations in peripheral temperature are observable using wearable devices and correlate with self-reported fever. Our analyses support the hypothesis that wearable sensors can detect illnesses in the absence of symptom recognition. Finally, these data support the hypothesis that prediction of illness onset is possible using continuously generated physiological data collected by wearable sensors. Our findings should encourage further research into the role of wearable sensors in public health efforts aimed at illness detection, and underscore the importance of integrating temperature sensors into commercially available wearables."