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Dennis OConnor

Infographic Time: Age isn't Just a Number, it's Yours to Control! - Elite HRV - 1 views

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    Everyone ages at different rates. Our "true age" (also called "biological age") depends on how much inflammation we encounter in our lifestyle and environment, combining with our genetics. True age represents our capacity for resilience, in tolerating and recovering from these life stresses. By increasing this resilience, we could even get younger in true age! It requires frequent tracking of biomarkers like heart rate variability (HRV).
Dennis OConnor

UC San Diego Center for Healthy Aging - 0 views

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    In 2014, UC San Diego Health Sciences created The Center for Healthy Aging, which now serves as an umbrella organization for all aging-related programs at UC San Diego and expands upon the work of the Stein Institute for Research on Aging. Its focus extends beyond medical research to address the major challenges facing our society as it prepares to accommodate a rapidly expanding demographic of older adults-in terms of technology, finances, housing, transportation and urban planning.
Dennis OConnor

Empowered Patient Podcast: Overcoming Fear of Aging with Heidi Rataj Documentary Produc... - 1 views

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    "Heidi Rataj is an award-winning documentary producer and director and a caregiver for her mom.  Heidi talks about her own fear of aging and the search for a new narrative for seniors as they age.  While we need to be respectful of all journeys, activating seniors to allow them to accomplish goals is key to a healthier individual and society.  She also points out how digital technology plays a role in coordinating care and enabling people to age in place. @UCSDHealthyAging"
Dennis OConnor

At the Cusp of Solving Cognitive Aging? - Mike Merzenich - Medium - 0 views

  • Bookmark story
  • the ACTIVE Study.
  • hree different theories
  • ...24 more annotations...
  • memory
  • reasoning
  • speed of processing
  • ACTIVE tracked people for 10 years
  • 74 to 84
  • who would have expected faster cognitive processing speed 10 years later
  • The big question was do those gains transfer to real-world activities.And, the answer is: they do.
  • At the end of 10 years
  • about three years more protection against decline
  • speed training
  • ● 38% less risk of onset of depressive symptoms● 30% less risk of deepening of depressive symptoms● 68% stronger feeling of confidence and control● 48% less risk of at-fault car crashes
  • I (Mike Merzenich) have spent decades studying brain plasticity — the brain’s ability to change (at any age), chemically, structurally and functionally.
  • What changes in the brain as it gets older?
  • basic science question
  • every single thing we measured in the aging brain changed (and none for the better).
  • The top row
  • we built a brain-training program designed to make a rat’s brain faster and more accurate.
  • to improve auditory precision and speed.
  • It turns out that this kind of brain training — continuously and progressively challenging the speed and accuracy of brain processing — improves every aspect of brain health we could measure.
  • we could build, test, refine and validate a training program to improve all the major systems of the brain.
  • plasticity-based training
  • cognition (eg, speed, attention, memory, executive function)
  • quality of life (eg, mood, confidence, self-rated health)
  • dementia?
Dennis OConnor

Aging Successfully | Conversation | re'flect - 0 views

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    "Gray Matters, the new podcast series, will continue our mission to discuss how we can all age successfully.   re'flect, the documentary series has aired nationally on over 50 PBS stations in over 40 cities and is spreading the positive aging conversation around the US. "
Dennis OConnor

Team | reflect-copy - 1 views

  • HEIDI RATAJ
  • THERESA HOILES
  • PRODUCER, DIRECTOR & SPEAKE
  • ...5 more annotations...
  • PRODUCER & WRITER
  • What’s more important, quality of life or quantity?”
  • Theresa learned early that age is not an excuse to slow down.
  • Through storytelling, she wants to break the stereotypes associated with aging.
  • This series convinced Heidi that life should be measured in quality not quantity
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    "Gray Matters, the new podcast series, will continue our mission to discuss how we can all age successfully. Heidi Rataj, MA Producer, Gerontologist & Entrepreneur re'flect, the documentary series has aired nationally on over 50 PBS stations in over 40 cities and is spreading the positive aging conversation around the US. "
Dennis OConnor

The Ultimate Guide To Red Light Therapy And Near-Infrared Light Therapy (Updated 2018) ... - 0 views

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    "As people come to realize that you can get all the amazing benefits of near-infrared and red light therapy without spending $5,000-$30,000 on a laser device or $75-$300 for a single treatment session in an anti-aging clinic, I believe this therapy will go mainstream and nearly everyone will have a red/NIR light therapy device in their home. After all, who wouldn't want to have a simple-to-use device in their home that can dramatically speed healing, improve hormonal health, accelerate fat loss, increase energy, and combat skin aging?"
Dennis OConnor

Lancet: Effectiveness of wearable activity trackers to increase physical activity and i... - 0 views

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    "Summary Wearable activity trackers offer an appealing, low-cost tool to address physical inactivity. This systematic review of systematic reviews and meta-analyses (umbrella review) aimed to examine the effectiveness of activity trackers for improving physical activity and related physiological and psychosocial outcomes in clinical and non-clinical populations. Seven databases (Embase, MEDLINE, Ovid Emcare, Scopus, SPORTDiscus, the Cochrane Library, and Web of Science) were searched from database inception to April 8, 2021. Systematic reviews of primary studies using activity trackers as interventions and reporting physical activity, physiological, or psychosocial outcomes were eligible for inclusion. In total, 39 systematic reviews and meta-analyses were identified, reporting results from 163 992 participants spanning all age groups, from both healthy and clinical populations. Taken together, the meta-analyses suggested activity trackers improved physical activity (standardised mean difference [SMD] 0·3-0·6), body composition (SMD 0·7-2·0), and fitness (SMD 0·3), equating to approximately 1800 extra steps per day, 40 min per day more walking, and reductions of approximately 1 kg in bodyweight. Effects for other physiological (blood pressure, cholesterol, and glycosylated haemoglobin) and psychosocial (quality of life and pain) outcomes were typically small and often non-significant. Activity trackers appear to be effective at increasing physical activity in a variety of age groups and clinical and non-clinical populations. The benefit is clinically important and is sustained over time. Based on the studies evaluated, there is sufficient evidence to recommend the use of activity trackers."
Dennis OConnor

Wearable device signals and home blood pressure data across age, sex, race, ethnicity, ... - 0 views

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    Full Text PDF available: "Wearable device signals and home blood pressure data across age, sex, race, ethnicity, and clinical phenotypes in the Michigan Predictive Activity & Clinical Trajectories in Health (MIPACT) study: a prospective, community-based observational study"
Dennis OConnor

San Diego Community News Group - La Jolla doctor donates late father s tissue to help L... - 0 views

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    "Before now, La Jolla biochemist Dr. Sharon Wampler never spoke publicly about the controversy that plagued her father's battle with Lyme Disease. Sharon's father, Whitfield (W.E.) Wampler, was age 92 when he passed away August of 2016. While it's unknown exactly how long W.E. lived with Lyme, his more severe symptoms-including joint failure and loss of hearing and eyesight-spanned over ten years."
Dennis OConnor

Crohnology - 0 views

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    "I started Crohnology because after living for Crohn's for 14 years, I realized that the data that I was gathering outside the doctor's office was just as important as, if not more than, what I was learning inside. Since my diagnosis at age 12, I have had a dozen major flare ups of the disease. I found that, for me, diets and supplements, stress reduction and mental relaxation, and exercise help. I heard many people on the internet claim that they had found the magic bullet, but I thought it was irresponsible to be so confident. Just because these things worked for me, I wasn't about to claim that they work for everybody. Instead, I decided to build a patient-powered research network that would allow patients everywhere to be contributing their own treatment experimentation in a way that could be aggregated for us to learn what actually works for whom. - Sean Ahrens"
Dennis OConnor

EMPOWEREDPATIENTPODCAST.COM - 0 views

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    Welcome to the Empowered Patient Podcast with Karen Jagoda. This show is a window into the latest innovations in digital health and the changing dynamic between doctors and patients. Topics on the show include the emergence of personalized medicine and breakthroughs in genomics advances for aging in place using big data from wearables and sensors transparency in the medical marketplace challenges for connected health entrepreneurs The audience includes researchers, medical professionals, patient advocates, entrepreneurs, patients, caregivers, solution providers, students, journalists, and investors.
Dennis OConnor

JMIR - Journal of Medical Internet Research - 0 views

shared by Dennis OConnor on 31 Oct 19 - Cached
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    "Journal of Medical Internet Research The leading peer-reviewed journal for digital medicine and health and health care in the internet age"
Dennis OConnor

Empowered Patient Podcast: When the Patient is a Medical Mystery with Cathy Miller - 0 views

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    "Welcome to the Empowered Patient Podcast with Karen Jagoda.  This show is a window into the latest innovations in digital health and the changing dynamic between doctors and patients. Topics on the show include the emergence of personalized medicine and breakthroughs in genomics advances for aging in place using big data from wearables and sensors transparency in the medical marketplace challenges for connected health entrepreneurs The audience includes researchers, medical professionals, patient advocates, entrepreneurs, patients, caregivers, solution providers, students, journalists, and investors."
Dennis OConnor

What is biohacking? The new "science" of optimizing your brain and body. - Vox - 0 views

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    "Biohacking - also known as DIY biology - is an extremely broad and amorphous term that can cover a huge range of activities, from performing science experiments on yeast or other organisms to tracking your own sleep and diet to changing your own biology by pumping a younger person's blood into your veins in the hope that it'll fight aging. "
Dennis OConnor

VIP NeuroRehabilitation Center - VIP NeuroRehab - San Diego Spinal Cord Injury, MS, CP,... - 0 views

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    "VIP NeuroRehabilitation Center is a non-profit 501(c)(3) organization, run by and for the patients! We bring top quality outpatient NeuroRehabilitation care to disabled military, veterans, children, and to ALL who are in need.  Located in San Diego, California, we treat adult and pediatric patients, from ages 4 years old and up. Our focus is on those who have difficulty moving secondary to Stroke, Multiple Sclerosis (MS), Brain Injury, ALS, Cerebral Palsy, Spinal Cord Injury, and multiple traumas."
Dennis OConnor

omkara-life-coaching - 0 views

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    I met Tahir Bhatti during my Ornish Lifestyle Medicine transformation at Jacobs Medical Center UCSD. Tahir would sub into our support group whenever Ozzie Gontang was traveling. He is a great teacher. "Holistic Healers, Wellness Coaches, and Life-partners, Tahir Bhatti & Ayesha Suneja  have spent the last 20 years researching, teaching and guiding others towards mind-body-spirit healing, transpersonal wellness and spiritual growth.   Originally from India and Pakistan, both Ayesha and Tahir were raised in cultures that naturally cultivated spirituality, meditation and holistic healing practices.   Their passion for integrating spirituality into their clinical work led them to further their studies in Eastern philosophy, meditation, soul consciousness and self-realization.   Due to their exposure to ancient Eastern philosophies at a young age and their extensive training in Western Medicine & Psychology, their eclectic studies are balanced in the Sciences and the Ancient Truths.     By integrating both philosophies Tahir and Ayesha have created a blend of Eastern and Western Coaching Practices that is truly unique."
Dennis OConnor

Dr. Mignosa | Dr. Mignosa - 1 views

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    "Dr. Mignosa had the opportunity to transform his own experience with injuries and pain through an integrative approach to healing. During his teenage years, he was an avid athlete who battled constant injuries. Eventually, a surgeon told him that he should quit running. At the age of 16, Dr. Mignosa rejected this opinion and questioned the mindset of how medicine treats disorders of structure and function. Instead, he embraced a mindset of building health and focused on educating himself on health and healing."
Dennis OConnor

What We Know So Far About SARS-CoV-2 - The Atlantic - 0 views

  • March 20, 2020
  • One of the few mercies during this crisis is that, by their nature, individual coronaviruses are easily destroyed.
  • These viruses don’t endure in the world. They need bodies.
  • ...30 more annotations...
  • To be clear, SARS-CoV-2 is not the flu. It causes a disease with different symptoms, spreads and kills more readily,
  • his family, the coronaviruses, includes just six other members that infect humans
  • OC43, HKU1, NL63, and 229E—have been gently annoying humans for more than a century, causing a third of common colds
  • MERS and SARS (or “SARS-classic,” as some virologists have started calling it)—both cause far more severe disease.
  • hy was this seventh coronavirus the one to go pandemic?
  • The structure of the virus provides some clues about its success. In shape, it’s essentially a spiky ball. Those spikes recognize and stick to a protein called ACE2
  • This is the first step to an infection
  • he exact contours of SARS-CoV-2’s spikes allow it to stick far more strongly to ACE2 than SARS-classic did
  • But in SARS-CoV-2, the bridge that connects the two halves can be easily cut by an enzyme called furin, which is made by human cells and—crucially—is found across many tissues. “This is probably important for some of the really unusual things we see in this virus,” says Kristian Andersen of Scripps Research Translational Institute.
  • SARS-CoV-2 seems to infect both upper and lower airways,
  • his double whammy could also conceivably explain why the virus can spread between people before symptoms show up
  • All of this is plausible but totally hypothetical; the virus was only discovered in January, and most of its biology is still a mystery.
  • The closest wild relative of SARS-CoV-2 is found in bats, which suggests it originated in a bat, then jumped to humans either directly or through another species.
  • Another coronavirus found in wild pangolins also resembles SARS-CoV-2
  • Indeed, why some coronaviruses are deadly and some are not is unclear. “There’s really no understanding at all of why SARS or SARS-CoV-2 are so bad but OC43 just gives you a runny nose,” Frieman says.
  • Once in the body, it likely attacks the ACE2-bearing cells that line our airways.
  • The immune system fights back and attacks the virus; this is what causes inflammation and fever
  • in extreme cases, the immune system goes berserk
  • These damaging overreactions are called cytokine storms.
  • they’re probably behind the most severe cases of COVID-19.
  • During a cytokine storm, the immune system isn’t just going berserk but is also generally off its game, attacking at will without hitting the right targets.
  • But why do some people with COVID-19 get incredibly sick, while others escape with mild or nonexistent symptoms
  • Age is a factor.
  • other factors—a person’s genes, the vagaries of their immune system, the amount of virus they’re exposed to, the other microbes in their bodies
  • “it’s a mystery why some people have mild disease, even within the same age group,”
  • Coronaviruses, much like influenza, tend to be winter viruses.
  • In the heat and humidity of summer, both trends reverse, and respiratory viruses struggle to get a foothold.
  • irus is tearing through a world of immunologically naive people, and that vulnerability is likely to swamp any seasonal variations.
  • And one recent modeling study concluded that “SARS-CoV-2 can proliferate at any time of year.
  • Unless people can slow the spread of the virus by sticking to physical-distancing recommendations, the summer alone won’t save us.
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    Dr. Michael Kurisu D.O.: We've known about SARS-CoV-2 for only three months, but scientists can make some educated guesses about where it came from and why it's behaving in such an extreme way.
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