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"Our mission is to improve public health through prevention research, education, and clinical care." The department's clinical care and community-based initiatives aim to transform health care in San Diego through the practice of family medicine, preventive medicine, sports medicine, integrative medicine, and research that is practice-based. We have a robust portfolio of innovative clinical and public health focused research projects that address contemporary public health challenges through tools from biostatistics/bioinformatics, behavioral medicine, epidemiology, policy, and dissemination and implementation science. We have established Centers of Excellence in cardiovascular epidemiology, health behavior and equity, integrative health, tobacco control, wireless and population health, and women's health. Innovative, interdisciplinary partnerships are ongoing with Qualcomm Institute/Calit2, Moores Cancer Center, the Scripps Institute of Oceanography, Center for Microbiome Innovation, and many other departments.

January 28, 2021 Dear KRI Research Team, I am very pleased to announce that our latest article "Spiritual Fitness: A New Dimension In Alzheimer's Prevention" which I co-authored with ARPF SAC member, Andrew Newberg, M.D. of Thomas Jefferson University, has been accepted for publication by The Journal of Alzheimer's Disease. Dharma Singh Khalsa, M.D. Founding President / Medical Director Alzheimer's Research and Prevention Foundation (ARPF) www.alzheimersprevention.org drdharma@alzheimersprevention.org

by Donald M. Berwick, MD, MPP1 How do humans invest in their own vitality and longevity? The answer seems illogical. In wealthy nations, science points to social causes, but most economic investments are nowhere near those causes. Vast, expensive repair shops (such as medical centers and emergency services) are hard at work, but minimal facilities are available to prevent the damage.

Recommended by Sharon Wampler "ABSTRACT Lyme disease (LD) is an increasing public health problem. Current laboratory testing is insensitive in early infection, the stage at which appropriate treatment is most effective in preventing disease sequela. The Lyme Disease Biobank (LDB) collects samples from individuals with symptoms consistent with early LD presenting with or without erythema migrans (EM) or an annular, expanding skin lesion, and uninfected individuals from endemic areas. Samples were collected from 550 participants (298 cases and 252 controls) according to IRB-approved protocols and shipped to a centralized biorepository. Testing was performed to confirm the presence of tick-borne pathogens by real-time PCR, and a subset of samples was tested for Borrelia burgdorferi by culture. Serology using the CDC's standard two-tiered testing algorithm (STTTA) for LD was performed on all samples. LD diagnosis was supported by laboratory testing in 82 cases, including positive STTTA, PCR, culture, or 2 positive ELISA's with EM >5 cm, while the remaining 216 cases had negative laboratory testing results. For the controls, 43 were positive on at least one of the tiers, and 6 were positive by STTTA. This collection highlights and reinforces the known limitations of serologic testing in early LD, with only 29% of individuals presenting with EM >5 cm yielding a positive result using the STTTA. Aliquots of whole blood, serum, and urine from clinically characterized patients with and without LD are available to investigators in academia and industry for evaluation or development of novel diagnostic assays for LD, to continue to improve upon currently available methods."

"Meet Milli A self-teaching personalized medical intelligence platform built from real-time analysis of millions of patient/doctor interactions. The Medical Intelligence Platform™ makes it easy to capture, aggregate, and analyze comprehensive patient data with human-augmented Artificial Intelligence. We provide doctors with suggestions for the likely underlying dysfunctions that lead to disease, recommendations for follow up tests, and predictions for which intervention will be most effective for each patient. Our Virtual Health Assistant then provides intervention support to the patient and tracks their adherence and medical outcomes. This closed-loop process enables the platform to systematically learn from every provider/patient medical encounter to learn how to better prevent and reverse disease."

Recommended by Dr. Michael Kurisu D.O.: There is a high level of interest in integrative strategies to augment public health measures to prevent COVID-19 infection and associated pneumonia. Unfortunately, no integrative measures have been validated in human trials. Notwithstanding, this is an opportune time to be proactive. Using available in-vitro evidence, an understanding of the virulence of COVID-19, as well as data from similar, but different, viruses, we offer the following strategies to consider. Again, we stress that these are supplemental considerations to the current recommendations that emphasize regular hand washing, social distancing, stopping non-essential travel, and getting tested if you develop symptoms.

Recommended by DeAunne Denmark, MD, PhD : "The projects these companies are working on can be organized into three distinct groups: Diagnostics: Quickly and effectively detecting the disease in the first place Treatments: Alleviating symptoms so people who have disease experience milder symptoms, and lowering the overall mortality rate Vaccines: Preventing transmission by making the population immune to COVID-19"

Recommended by Jessica Block "My name is David Treleaven. I'm a writer, educator, and trauma professional who teaches people to offer mindfulness in a trauma-sensitive way. Unbeknownst to many, mindfulness meditation can exacerbate symptoms of traumatic stress. Instructed to pay close, sustained attention to their inner-world, people struggling with trauma can experience flashbacks, dysregulation, or dissociation.  On this site, you'll find resources designed to prevent this while leveraging the power of mindfulness towards trauma recovery."

"Precise. Personalized. Prevention. Express your best DNA - the power to impact genetic expression is in your hands. Epigenetics is the study of how lifestyle & environment influence the expression of your genes." OUR MISSION is to empower and inspire providers and patients in optimizing genetic potential through precise, personalized protocols that positively impact patients' health and future generations.

"Tuesday, August 18, 2020 Articles referenced: Systems entrepreneurship: a conceptual substantiation of a novel entrepreneurial "species" https://link.springer.com/article/10.... Your 'Surge Capacity' Is Depleted - It's Why You Feel Awful https://elemental.medium.com/your-sur... The Role Of Empathy and Compassion In Preventing Burnout https://medium.com/thrive-global/the-..."

"The National Institutes of Health today announced a new initiative aimed at speeding innovation, development and commercialization of COVID-19 testing technologies, a pivotal component needed to return to normal during this unprecedented global pandemic. With a $1.5 billion investment from federal stimulus funding, the newly launched Rapid Acceleration of Diagnostics (RADx) initiative will infuse funding into early innovative technologies to speed development of rapid and widely accessible COVID-19 testing. At the same time, NIH will seek opportunities to move more advanced diagnostic technologies swiftly through the development pipeline toward commercialization and broad availability. NIH will work closely with the U.S. Food and Drug Administration, the Centers for Disease Control and Prevention and the Biomedical Advanced Research and Development Authority (BARDA) to advance these goals."

"You can be an empowered patient or advocate by knowing the basics of HIPAA and having the confidence to request records from providers. Here are some myths about HIPAA and how they affect you, the patient."

"Rachelle Babler explores the untapped powers of combining music and advocacy to create human impact. She did this after losing her sister to colon cancer to create awareness around prevention and screening. The response was overwhelming. While many have advocated through speeches, fundraisers and media, very few advocate through songwriting and music. Maybe music will be the critical voice that creates the awakening to help us unite, during times of chaos and separation. When we are divided by speech, we can be united and reunited through the power of song. Rachelle Babler grew up in Southern California near the sunny beaches of San Diego and has always been an avid explorer, traveler, musician and creative soul. At the height of her career in forensics, she quit her job cold turkey to pursue her "why" and found out what that was during a global pandemic, "TO empower others to consciously advocate, SO THAT they can heal, inspire and unite the human collective". She is a #1 International Best Selling Co-Author, Speaker, Advocate. Singer/Songwriter and proud mother to her two amazing children, Austin and Camryn. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx"

Recommended by Dr. Michael Kurisu D.O. 4/15/2020 Good summary. Not scientific or too detailed but good overall big picture view

" CONNECT WITH US: ABOUT PMRI RESEARCH CONTACT US DONATE Alzheimer's Study Can Lifestyle Changes Reverse Alzheimer's Disease?"

DeAunne Denmark, M.D. Phd - I was just reading about this last night. Dr forum blowing up about it. It could be a gigantic win for EverlyWell (and at-home D-T-C Direct-to-Consumer) if they do it right. But *must* do it right, e.g. including transparency re: methods, interfacing with HCP/EMRs, etc. The big issue may be collection variability, not unlike the microbiome. Nasal swab not trivial, more talk now about collection variability possibly accounting for a large proportion of "negs" turning positive. Hate to see a lot of false confidence running around at large infecting others.