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Dennis OConnor

Creating a new tool for pain: The CHOIR body map puts pain on the map | Pain News - 0 views

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    "A new electronic self-report body map is an innovative tool for precision health." The CHOIR body map is validated in almost 600 people with chronic pain. Our results demonstrated excellent performance of the map in all of these validation studies. Furthermore, we used the interviews with participants and their suggestions to further optimize the body map. Clinicians and researchers have used the CHOIR body map in over 100,000 assessments across the CHOIR network worldwide.
Dennis OConnor

Development and validation of the Collaborative Health Outco... : PAIN Reports - 0 views

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    Open Access. Abstract Introduction: Critical for the diagnosis and treatment of chronic pain is the anatomical distribution of pain. Several body maps allow patients to indicate pain areas on paper; however, each has its limitations. Objectives: To provide a comprehensive body map that can be universally applied across pain conditions, we developed the electronic Collaborative Health Outcomes Information Registry (CHOIR) self-report body map by performing an environmental scan and assessing existing body maps. Methods: After initial validation using a Delphi technique, we compared (1) pain location questionnaire responses of 530 participants with chronic pain with (2) their pain endorsements on the CHOIR body map (CBM) graphic. A subset of participants (n = 278) repeated the survey 1 week later to assess test-retest reliability. Finally, we interviewed a patient cohort from a tertiary pain management clinic (n = 28) to identify reasons for endorsement discordan
Dennis OConnor

SimplySarno - Dr John Sarno, Back and Body Pain Doctor - 0 views

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    "Starting with an open-mind, questioning the foundational science, and conducting his own studies, Dr. Sarno discovered something revolutionary - the cause of most chronic back and body pain is not due to an underlying physical issue, but a specific way the brain and body interact.   "
Dennis OConnor

Precision Health: Know More About Your Body, Worry Less | Q Bio - 1 views

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    In 2008 Jeff Kaditz was rushed to the hospital after being hit by a car. He spent months in a hospital bed and had to learn to walk again. He was misdiagnosed twice before finding out he needed major surgery. Throughout the process he was frustrated by the lack of quantitative information that was available about his body, which led to a wide range of inconsistent diagnoses. Jeff imagined a day when everything about a person's body could be quickly measured, shared and analyzed. He started researching a solution and in 2015 he met Dr. Michael Snyder and Dr. Garry Choy. They immediately bonded over a shared vision that became Q.
Dennis OConnor

Do infrared saunas have any health benefits? - Mayo Clinic - 0 views

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    "An infrared sauna is a type of sauna that uses light to create heat. This type of sauna is sometimes called a far-infrared sauna - "far" describes where the infrared waves fall on the light spectrum. A traditional sauna uses heat to warm the air, which in turn warms your body. An infrared sauna heats your body directly without warming the air around you."
Dennis OConnor

It's Not About Feeling Better. It's About Accepting My Body As It Is. - 0 views

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    It's Not About Feeling Better. It's About Accepting My Body As It Is. "If my journey with invisible illness has taught me anything, it's that I have to be my own best advocate."
Dennis OConnor

The Quantification of Placebo Effects Within a General Model of Health Care Outcomes - 1 views

  • It is proposed that the integration of a scientific model of placebo effects within a general model of health care outcomes could finally end the placebo debate and help to integrate these powerful effects into the health care system.
  • Positive expectancy is recognized as a central component of placebo phenomena by all placebo theorists
  • The proposed model emphasizes that the search for a placebo personality factor must be combined with the measurement of situational expectancy.
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  • an individual who has negative expectations regarding treatment effectiveness would likely produce a stronger than average “nocebo” effec
  • placebo-prone personality
  • Absorption
  • receptivity to sensory experiences and a propensity for sustained, focused attention.
  • Absorption has a genetic basis and is higher in women compared to men
  • Absorption can go in either a positive or negative direction, depending on the situation,
  • Subjects were randomly
  • outcome measures
  • based on three scales
  • includes scales measuring fatigue, pain, and spasticity
  • Judgment that the placebo was the active device resulted in a positive score with a magnitude of the confidence rating.
  • if judgment was that the placebo was the placebo device, the confidence rating of the placebo was a negative score, with the magnitude of the rating.
  • scored in the upper quintile on improved quality of life, as measured by the 3 QLI (an average of three symptom scales measuring pain, fatigue, and spasticity) after receiving treatment with a sham device.
  • placebo responders
  • Placebo responders scored higher on Absorptio
  • Placebo responders gave higher confidence ratings that the placebo was the active device
  • This study provides support for a two-factor model of placebo responding.
  • importance of positive expectancy
  • both cognitive and emotional factors mediate these effects
  • Positive beliefs or confidence in the treatment coupled with a desire to feel better activate processes that result in positive outcomes.
  • positive expectancy is an essential factor
  • disease-specific pathways that are activated by positive expectancies have helped to transform this “soft” psychologic factor into a “hard” physiologic factor with physically measurable effects.
  • While the shift from negative to positive affect may be the hallmark of placebo responding, negative affect alone is not sufficient and can play a role in people who worsen as well (nocebo effects).
  • Numerous research studies have reliably shown that Absorption is modestly (yet very consistently) correlated with hypnotizability.
  • Hypnotizability is often associated with “suggestibility,” with perhaps the sense of a weak-willed character or unbridled fantasy-proneness, the “unreality factor” that has plagued placebo theory for decades.
  • enlightening to view these individual differences as a natural endowment in self-regulation skills: a potential innate strength rather than a simple weakness with a natural ability for self-directed healing in response to health challenges.
  • Decades of research have reliably demonstrated that individuals scoring high in Absorption can skillfully modulate an impressive array of physiologic processes in laboratory settings.
  • The literature suggests that the mind–body control of high Absorption scorers is similar to the self-regulation skills that many are seeking to develop with meditation, mindfulness, yoga, and qigong.
  • The regular practice of mind–body control and the cultivation of positive attitudes may enhance regulation at higher levels, improving the regularity of circadian and other rhythms,
  • points to the role of both expectation and conditioning, with conditioning playing a greater role in certain pathways such as immune modulation.
  • somatic vulnerability of high Absorption individuals who suffer from negative biases in perception.
  • nocebo phenomena described by these researchers are important for our model as they directly illustrate the power of a negative interaction of the two factors.
  • Many physicians admit to prescribing placebos to contribute to patient wellness, even though this “dark secret” is not condoned and is considered to be ethically questionable.
  • High Absorption individuals may benefit from encouragement to utilize their innate self-regulation skills toward maximum therapeutic effect.
  • ersons with average Absorption scores can be encouraged to become more skilled at self-regulation through mind–body therapies
  • The model does not specifically address the many factors that contribute to confidence in the treatment, such as cost, pill color, pill size, or confidence-enhancing paraphernalia.
  • The role of provider and patient interaction are also not specifically addressed.
  • he model also does not directly address the role of stress reduction
  • The strength of placebo responding in domains such as pain and depression clearly indicate the importance of the shift from a negative to a positive state.
  • the unresolved issue of why some people respond to placebos whereas others do not
  • asic two-factor model can be further tested with the basic measurement tools of expectancy and Absorption,
  • Conclusions
  • the recognition that positive expectancy and expert self-regulation skills significantly contribute to health outcomes can help to integrate these powerful effects into the health care system
  • The “positive psychology” movement is shifting attention to the power of positive expectation
  • undermining nature of negative expectancy and pessimistic language, especially in vulnerable populations such as those with pain and depression
  • Practitioners of the art of health care have always recognized the importance of motivated and empowered patients and the power of a kind word and a ray of hope.
  • This is the time to quantify these factors, integrating art and science, and finally solving (and forgiving Descartes for) the mind–body problem.
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    "The topic of placebo effects is distinguished by decades of keen scientific interest1-4 coupled with a general skepticism regarding the ultimate significance of these phenomena. The importance of psychologic factors in mediating these effects may contribute to the attitude that placebo effects are not as substantial as a therapeutic effect produced by a drug. Complementary and alternative therapies have sometimes been dismissed as "mere placebos." However, recent studies have provided compelling evidence that placebo effects are physiologically measurable with condition-specific pathways.5"
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    Dr. Jake Fleming recently suggested these potent keywords: quantifiable placebo The keywords led to this article. I find it affirming and empowering.
Dennis OConnor

Long-Haulers Are Redefining COVID-19 - The Atlantic - 2 views

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    "Without clear information from official sources, many long-haulers have found answers from one another. Support groups on Facebook have thousands of members. One Slack group, founded within a wellness organization called Body Politic, has almost doubled in size since June to more than 7,000 active participants from 25 countries. There are channels for discussing every organ system in the body. There are lists of sympathetic medical providers, and tips for convincing those who aren't listening. Eerily, the group's membership morphs as the pandemic spreads: "When Brazil had a huge spike, we had a massive influx of Brazilian patients," said Nichols, who is an administrator."
Dennis OConnor

UCSD Smarr lab - 0 views

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    "Understanding how life uses time to improve health, education, and the world. Life on Earth is the living embodiment of information's value. Now that individuals generate data across time with digital trails and wearable sensors, we can begin to see how humans evolved to use time to orchestrate their bodies. Modern life often conflicts with natural time by imposing social demands that go against the rhythms of our bodies. The more we learn about time in our lives (and the lives of all organisms), the more informed can be our personal and societal choices about how we use time in this modern context for which we are not so well adapted. Ongoing projects are listed below, but are not exhaustive. While they may seem disparate, they are united in generating examples of the opportunities that incorporating biological time seems to offer across fields and across populations. I encourage any and all to reach out if they are interested in biological time and/or how data can influence your life. Student projects are welcome, as are academic and private collaborations with a goal of sharing information."
Dennis OConnor

Knight Lab - 0 views

  • The Knight Lab uses and develops state-of-the-art computational and experimental techniques to ask fundamental questions about the evolution of the composition of biomolecules, genomes, and communities in different ecosystems, including the complex microbial ecosystems of the human body. We subscribe to an open-access scientific model, providing free, open-source software tools and making all protocols and data publicly available in order to increase general interest in and understanding of microbial ecology, and to further public involvement in scientific endeavors more generally.
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    Rob Knight PHD, Embriette Hyde PHD, Sandrine Miller Montgomery PharmD PHD The Knight Lab uses and develops state-of-the-art computational and experimental techniques to ask fundamental questions about the evolution of the composition of biomolecules, genomes, and communities in different ecosystems, including the complex microbial ecosystems of the human body. We subscribe to an open-access scientific model, providing free, open-source software tools and making all protocols and data publicly available in order to increase general interest in and understanding of microbial ecology, and to further public involvement in scientific endeavors more generally.
Dennis OConnor

What We Know So Far About SARS-CoV-2 - The Atlantic - 0 views

  • March 20, 2020
  • One of the few mercies during this crisis is that, by their nature, individual coronaviruses are easily destroyed.
  • These viruses don’t endure in the world. They need bodies.
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  • To be clear, SARS-CoV-2 is not the flu. It causes a disease with different symptoms, spreads and kills more readily,
  • his family, the coronaviruses, includes just six other members that infect humans
  • OC43, HKU1, NL63, and 229E—have been gently annoying humans for more than a century, causing a third of common colds
  • MERS and SARS (or “SARS-classic,” as some virologists have started calling it)—both cause far more severe disease.
  • hy was this seventh coronavirus the one to go pandemic?
  • The structure of the virus provides some clues about its success. In shape, it’s essentially a spiky ball. Those spikes recognize and stick to a protein called ACE2
  • This is the first step to an infection
  • he exact contours of SARS-CoV-2’s spikes allow it to stick far more strongly to ACE2 than SARS-classic did
  • But in SARS-CoV-2, the bridge that connects the two halves can be easily cut by an enzyme called furin, which is made by human cells and—crucially—is found across many tissues. “This is probably important for some of the really unusual things we see in this virus,” says Kristian Andersen of Scripps Research Translational Institute.
  • SARS-CoV-2 seems to infect both upper and lower airways,
  • his double whammy could also conceivably explain why the virus can spread between people before symptoms show up
  • All of this is plausible but totally hypothetical; the virus was only discovered in January, and most of its biology is still a mystery.
  • The closest wild relative of SARS-CoV-2 is found in bats, which suggests it originated in a bat, then jumped to humans either directly or through another species.
  • Another coronavirus found in wild pangolins also resembles SARS-CoV-2
  • Indeed, why some coronaviruses are deadly and some are not is unclear. “There’s really no understanding at all of why SARS or SARS-CoV-2 are so bad but OC43 just gives you a runny nose,” Frieman says.
  • Once in the body, it likely attacks the ACE2-bearing cells that line our airways.
  • The immune system fights back and attacks the virus; this is what causes inflammation and fever
  • in extreme cases, the immune system goes berserk
  • These damaging overreactions are called cytokine storms.
  • they’re probably behind the most severe cases of COVID-19.
  • During a cytokine storm, the immune system isn’t just going berserk but is also generally off its game, attacking at will without hitting the right targets.
  • But why do some people with COVID-19 get incredibly sick, while others escape with mild or nonexistent symptoms
  • Age is a factor.
  • other factors—a person’s genes, the vagaries of their immune system, the amount of virus they’re exposed to, the other microbes in their bodies
  • “it’s a mystery why some people have mild disease, even within the same age group,”
  • Coronaviruses, much like influenza, tend to be winter viruses.
  • In the heat and humidity of summer, both trends reverse, and respiratory viruses struggle to get a foothold.
  • irus is tearing through a world of immunologically naive people, and that vulnerability is likely to swamp any seasonal variations.
  • And one recent modeling study concluded that “SARS-CoV-2 can proliferate at any time of year.
  • Unless people can slow the spread of the virus by sticking to physical-distancing recommendations, the summer alone won’t save us.
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    Dr. Michael Kurisu D.O.: We've known about SARS-CoV-2 for only three months, but scientists can make some educated guesses about where it came from and why it's behaving in such an extreme way.
Dennis OConnor

Like Mind, Like Body Podcast - Curable Health - 0 views

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    "Can our thoughts and feelings really miraculously heal, or slowly destroy our physical health and well being? Join us as we interview top researchers, best-selling authors, and field experts about the astonishing ways the mind can affect the body. Powered by Curable, an online program that uses mindbody techniques to relieve chronic pain."
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    Keyword: Placebo
Dennis OConnor

'You are what you eat,' and now researchers know exactly what you're eating: Matching b... - 0 views

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    Date: July 7, 2022 Source: University of California - San Diego Summary: Researchers describe a new method to identify all of the unidentified molecules derived from food, providing a direct way to link molecules in diet to health outcomes. "Matching blood or stool samples to a reference database of foods reveals how much of our body chemistry is traceable to what we consume" An international team of scientists, led by researchers at University of California San Diego, report a new method called untargeted metabolomics to identify the vast number of molecules derived from food that were previously unidentified, but that appear in our blood and our stool.
Dennis OConnor

(12) Pelin Wood Thorogood | LinkedIn - 0 views

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    new project apollo patient. Co-Founder & President Company NameWholistic Research and Education Foundation Dates EmployedMay 2017 - Present Employment Duration1 yr 2 mos LocationGreater San Diego Area Wholistic Research and Education Foundation is a California-based nonprofit dedicated to exploring the health benefits of CBD-rich therapeutics. Our mission is to fund clinical and scientific research to better understand the "if, how and why" behind the potential healing power of hemp and cannabis across a multitude of ailments, as well as work to increase safe and legal access to those in need via advocacy and education. Co-Founder Company NameMana Artisan Botanics Dates EmployedMay 2017 - Present Employment Duration1 yr 2 mos LocationKona, Hawaii Mana Artisan Botanics is a purpose-driven hemp company based on the Big Island of Hawaii. We offer pure hemp extracts infused with sustainably grown Hawaiian herbs and spices - nature's mana. Each product is hand crafted artisan style, in small batches. We take great care to source our ingredients from conscientious farmers, supporting local and organic whenever available. All of our products are simple, pure and good for body and soil.
Dennis OConnor

NAD+ Science 101 - What Is NAD+ & Why It's Important | Elysium Health - 0 views

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    "NAD+ is essential to the creation of energy in the body and the regulation of pivotal cellular processes. Here's why it's so important, how it was discovered, and how you can get more of it."
Dennis OConnor

Randy's Club - Randy's Remedy hemp products, powered by Cannaka. - 0 views

shared by Dennis OConnor on 06 Jun 18 - No Cached
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    Recommended by Sharon Wampler Randy's Remedy products are powered by Cannaka, a botanically complete blend of natural cannabinoids and terpenes derived from hemp. Natural cannabinoids are active non-dietary ingredients that target the endocannabinoid system which is responsible for modulating homeostasis in the body. These active ingredients, combined with essential terpenes support the endocannabinoid system and promote a healthy inflammatory response. Developed by the Strause Group; Linda, Tyler, and Brendon Strause, Randy's Remedy are the products they wished they had when their husband and father, Randy, was diagnosed with glioblastoma multiforme, an incurable brain cancer. Together they helped develop Cannaka and Randy's Remedy products delivering all the healthful benefits of natural cannabinoids and terpenes from hemp.
Dennis OConnor

omkara-life-coaching - 0 views

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    I met Tahir Bhatti during my Ornish Lifestyle Medicine transformation at Jacobs Medical Center UCSD. Tahir would sub into our support group whenever Ozzie Gontang was traveling. He is a great teacher. "Holistic Healers, Wellness Coaches, and Life-partners, Tahir Bhatti & Ayesha Suneja  have spent the last 20 years researching, teaching and guiding others towards mind-body-spirit healing, transpersonal wellness and spiritual growth.   Originally from India and Pakistan, both Ayesha and Tahir were raised in cultures that naturally cultivated spirituality, meditation and holistic healing practices.   Their passion for integrating spirituality into their clinical work led them to further their studies in Eastern philosophy, meditation, soul consciousness and self-realization.   Due to their exposure to ancient Eastern philosophies at a young age and their extensive training in Western Medicine & Psychology, their eclectic studies are balanced in the Sciences and the Ancient Truths.     By integrating both philosophies Tahir and Ayesha have created a blend of Eastern and Western Coaching Practices that is truly unique."
Dennis OConnor

Chronic Pain Eased With Meditation And Lower Doses Of Opioids : Shots - Health News : NPR - 0 views

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    "To deal with chronic pain, Pamela Bobb's morning routine now includes stretching and meditation at home in Fairfield Glade, Tenn. Bobb says this mind-body awareness intervention has greatly reduced the amount of painkiller she needs. Jessica Tezak for NPR" ~ 6 minute listen
Dennis OConnor

Vicky Newman - a Registered Dietitian Nutritionist (RDN | Mindful Nutrition Solutions - 1 views

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    "I am a Registered Dietitian Nutritionist (RDN) specializing in an integrated and personalized approach to nutrition, health, and healing. I believe that food not only nourishes the body, but also nurtures the spirit, and is essential for optimal functioning - to be able to live life with exuberance no matter what our age."
Dennis OConnor

The Supplemental practices of Zhineng Qigong with Master Yuantong Liu - 0 views

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    "Dear Practitioners, It is with great pleasure that I announce Master Yuantong Liu from China will be guest teaching July 22 - 26th, 2019,  at Prince of Peace Abbey in Oceanside. In this retreat we will share powerful supplemental practices of Zhineng Qigong, to support or create a dynamic mind/body practice for yourself. These profound methods will noticeably raise your gongfu. Gongfu is your benefits and skills acquired from diligent practice. Prior experience in Qigong is not required. All are welcome."
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