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Dennis OConnor

About the Center | Center for Microbiome Innovation - 0 views

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    "The UC San Diego Center for Microbiome Innovation leverages the university's strengths in clinical medicine, bioengineering, computer science, the biological and physical sciences, data sciences and more to coordinate and accelerate microbiome research. We also develop methods for manipulating microbiomes for the benefit of human and environmental health."
Dennis OConnor

Does the Gut Microbiome Ever Fully Recover From Antibiotics? - The New York Times - 0 views

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    "Q. What are the consequences of taking antibiotics on your gut microbiome? Does the gut ever fully recover? A. Most gut bacteria recover quickly, but there can be long-lasting consequences from taking antibiotics. The changes, however, are not necessarily harmful. The gut microbiome, the roughly 10 trillion to 100 trillion bacteria and other microorganisms that live in the digestive tract, contributes to health by synthesizing vitamins, metabolizing drugs and fighting pathogens. Anything that disrupts the balance of microorganisms, such as antibiotics, which can kill both "good" and "bad" bacteria, has the potential to cause disease."
Dennis OConnor

UC San Diego receives $14m to drive precision nutrition - 0 views

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    "The Nutrition for Precision Health consortium includes $14.55 million to launch a new Microbiome and Metagenomics Center at UC San Diego. The center will analyze the microbiomes - communities of microbes and their genetic material - found in the stool samples of nutrition study participants. "
Dennis OConnor

Department of Family Medicine and Public Health | UC San Diego - 0 views

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    "Our mission is to improve public health through prevention research, education, and clinical care." The department's clinical care and community-based initiatives aim to transform health care in San Diego through the practice of family medicine, preventive medicine, sports medicine, integrative medicine, and research that is practice-based. We have a robust portfolio of innovative clinical and public health focused research projects that address contemporary public health challenges through tools from biostatistics/bioinformatics, behavioral medicine, epidemiology, policy, and dissemination and implementation science. We have established Centers of Excellence in cardiovascular epidemiology, health behavior and equity, integrative health, tobacco control, wireless and population health, and women's health. Innovative, interdisciplinary partnerships are ongoing with Qualcomm Institute/Calit2, Moores Cancer Center, the Scripps Institute of Oceanography, Center for Microbiome Innovation, and many other departments.
Dennis OConnor

About Knight Lab - American Gut - 0 views

  • The American Gut is based out of Rob Knight’s lab at the University of California, San Diego-meaning all samples provided by American Gut citizen science participants are processed by technicians working in the Knight lab.  The Knight lab is one of the largest microbiome research labs in the world, processing samples from hundreds of projects at a rate of ~100,000 per year. Notably, the protocols used by the lab to process these samples have been extensively tested and benchmarked and are freely available from the Earth Microbiome Project’s website.
Dennis OConnor

Sewage-handling robots help predict COVID-19 outbreaks in San Diego | EurekAlert! Scien... - 0 views

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    "From July to November 2020, Karthikeyan and team, led by Rob Knight, PhD, professor and director of the Center for Microbiome Innovation at UC San Diego, sampled sewage water to see if they could detect SARS-CoV-2, the virus that causes COVID-19. They could. But concentrating the wastewater proved to be a bottleneck -- it's a slow and laborious multi-step process."
Dennis OConnor

Micronoma Wins Bio-IT World Innovative Practices Award - 0 views

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    Machine learning and microbiome-driven liquid biopsy technology draws recognition for improving early cancer diagnosis and chances of survival
Dennis OConnor

Knight Lab - 0 views

  • The Knight Lab uses and develops state-of-the-art computational and experimental techniques to ask fundamental questions about the evolution of the composition of biomolecules, genomes, and communities in different ecosystems, including the complex microbial ecosystems of the human body. We subscribe to an open-access scientific model, providing free, open-source software tools and making all protocols and data publicly available in order to increase general interest in and understanding of microbial ecology, and to further public involvement in scientific endeavors more generally.
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    Rob Knight PHD, Embriette Hyde PHD, Sandrine Miller Montgomery PharmD PHD The Knight Lab uses and develops state-of-the-art computational and experimental techniques to ask fundamental questions about the evolution of the composition of biomolecules, genomes, and communities in different ecosystems, including the complex microbial ecosystems of the human body. We subscribe to an open-access scientific model, providing free, open-source software tools and making all protocols and data publicly available in order to increase general interest in and understanding of microbial ecology, and to further public involvement in scientific endeavors more generally.
Dennis OConnor

Ben Brown | Biosciences | Berkeley Lab - 0 views

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    "Department Head, Molecular Eco-Systems Biology, EGSB Computational Biologist Staff Scientist Environmental Genomics and Systems Biology Molecular Eco-Systems Biology Secondary Affiliation: Biological Systems and Engineering BioEngineering & BioMedical Sciences"
Dennis OConnor

First U.S. Company Announces an Upcoming Home COVID-19 Test | Time - 0 views

  • Food and Drug Administration allowed certified labs, including commercial lab testing companies, to develop and distribute COVID-19 tests on Feb. 29.
  • People can order the Everlywell COVID-19 test on the company’s website, after first answering questions about their basic health, symptoms and risk factors for the coronavirus disease. A doctor still needs to prescribe the test, so telemedicine doctors from PWNHealth, a national network of physicians who prescribe diagnostic tests, then reviews these answers to determine if a person qualifies for testing, based on criteria established by the Centers for Disease Control and Prevention.
  • Currently, because COVID-19 tests are not plentiful in the U.S., doctors are trying to rule out other respiratory diseases like flu first, and only ordering tests for people with symptoms who also have other risk factors for infection, such as being in close contact with others who have been diagnosed.
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  • If the telemedicine doctor decides to prescribe an Everlywell COVID-19 test, the company says it will send the $135 test kit in two days (customers can pay $30 more to receive the kit overnight).
  • As with many of the commercially available tests, this one extracts SARS-CoV-2, the virus behind COVID-19, from the sample and then probes for specific genetic signatures of the virus.
  • If the test is positive, the company also provides a full telemedicine consultation with one of around 200 physicians that is included in the cost of the test.
  • Everlywell says it is ready to ship 30,000 COVID-19 tests, and plans to expand the number of labs processing the sample
  • kits will depend on the availability of swabs for collecting samples
  • global shortage of swabs for any lab performing the test.
  • We’re working hard to ramp up weekly capacity to test 250,000 Americans,” says Cheek
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    DeAunne Denmark, M.D. Phd - I was just reading about this last night. Dr forum blowing up about it. It could be a gigantic win for EverlyWell (and at-home D-T-C Direct-to-Consumer) if they do it right. But *must* do it right, e.g. including transparency re: methods, interfacing with HCP/EMRs, etc. The big issue may be collection variability, not unlike the microbiome. Nasal swab not trivial, more talk now about collection variability possibly accounting for a large proportion of "negs" turning positive. Hate to see a lot of false confidence running around at large infecting others.
Dennis OConnor

7 Reasons to Add Agriculture to Your Community! - Leichtag Foundation - 0 views

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    "by Daron "Farmer D" Joffe In the past few years, the Urban Land Institute has recognized that integrating food and farming into urban, suburban and rural real estate development projects is a rapidly growing trend. In addition to creating a dynamic platform for food production, social engagement and education, farm-centric communities can also support more vibrant and just regional food systems.  Integrating farms into neighborhoods presents several benefits, here are seven reasons to add agriculture to your community."
Dennis OConnor

American Gut by American Gut Project (UC San Diego) - 0 views

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    "The Microsetta Initiative and its subsidiaries, including the American Gut Project, have pivoted to COVID-19 research, and are revising our kits to support this effort. We are working as hard as we can, but please be patient as these changes have required a complete overhaul of our infrastructure. Please check back soon: we are setting up a form to gather information about people who are interested in receiving a kit when they are ready."
Dennis OConnor

'You are what you eat,' and now researchers know exactly what you're eating: Matching b... - 0 views

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    Date: July 7, 2022 Source: University of California - San Diego Summary: Researchers describe a new method to identify all of the unidentified molecules derived from food, providing a direct way to link molecules in diet to health outcomes. "Matching blood or stool samples to a reference database of foods reveals how much of our body chemistry is traceable to what we consume" An international team of scientists, led by researchers at University of California San Diego, report a new method called untargeted metabolomics to identify the vast number of molecules derived from food that were previously unidentified, but that appear in our blood and our stool.
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