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The life science/biology course is divided into 12 instructional segments grouped into four sections. In the first section, From Molecules to Organisms: Structures and Processes, students develop models of how molecules combine to build cells and organisms (IS1 [Structure and Function]; IS2 [Growth and Development of Organisms]; IS3 [Organization for Matter and Energy Flow in Organisms]). In the second section, Ecosystems: Interactions, Energy, and Dynamics, students zoom out to the macroscopic scale to show how organisms interact (IS4 [Interdependent Relationships in Ecosystems]; IS5 [Cycles of Matter and Energy Transfer in Ecosystems]; IS6 [Ecosystem Dynamics, Functioning, and Resilience]; IS7 [Social Interactions and Group Behavior]). Students return to the role that DNA plays in inheritance during the third section, Heredity: Inheritance and Variation of Traits (IS8 [Inheritance of Traits]; IS9 [Variation of Traits]). The class ends tying together interactions at all these scales by explaining evolution and natural selection in Biological Evolution: Unity and Diversity (IS10 [Evidence of Common Ancestry and Diversity]; IS11 [Natural Selection]; IS12 [Adaptation and Biodiversity]). A vignette in IS12 illustrates the level of three-dimensional understanding students are expected to exhibit as a capstone of the course.

Variety of lesson resources

7:41 Explores classification in biology as well as taxonomy hierarchy: domain, kingdom, phylum, class, order, family, genus, and species with The Amoeba Sisters! This video also discusses the importance of scientific names and why classification can have major changes due to DNA and cell structure evidence.

This "clicker case" tells the story of "Hannah," a baby girl adopted by two loving parents who grows up with an uncontrolled appetite and develops severe early-onset obesity. Students follow Hannah's story as she develops excessive eating early in life, which her health care team is unable to explain. A visit to obesity specialists finally reveals the underlying cause of Hannah's obsession with food: extremely low levels of circulating leptin, a hormone that regulates appetite and body weight. It is further discovered that Hannah's leptin deficiency is due to a mutation in the LEP gene. As the story unfolds, students first work on unit conversions and BMI calculations to practice quantitative skills as well as graph and data interpretation skills. Students then apply their knowledge of DNA transcription, translation, and protein structure to answer questions based on figures from a 2019 study on LEP mutations. The case is best suited for high school and lower-level undergraduate biology courses.

article on key scientists

curricular unit on Genetic Research

The 1000 Genomes Project is an international collaboration to produce an extensive public catalog of human genetic variation, including SNPs and structural variants, and their haplotype contexts. This resource will support genome-wide association studies and other medical research studies. The genomes of about 2500 unidentified people from about 25 populations around the world will be sequenced using next-generation sequencing technologies. The results of the study will be freely and publicly accessible to researchers worldwide. Further information about the project is available in the About tab. Information about downloading, browsing or using the 1000 Genomes data is available in the Data tab.

Generate different mutations using a model which transcribes and translates.  Clear instructions are on the website.

Reference site for International Baccalaureate (IB) Biology course.

array of HS science lesson from non-profit Science Pioneers in Kansas City, MO

4:55 min Rosalind Franklin is a lesser-known hero in the famous story of DNA's discovery.