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3:00 video Transcription is a vital process in biological lifeforms. It is through this process that the biological roadmap encoded in a strand of DNA is used to produce a complementary RNA copy. The RNA can then go on to help produce the proteins and enzymes that power living organisms.

Interactive animation for transcription and translation

Taylor must write a report about a natural toxin while she is home from college on break. After a family dinner conversation about the latest attempt to poison a politician via a letter, Taylor decides to explore how ricin acts as a poison. Students work in small groups to help Taylor by working through figures from primary literature papers and exploring the use of an in vitro translation system, sucrose gradient fractionation and the effect of inhibiting various steps of translation.  A shorter, second day activity involves students looking further at the effect of ricin upon ribosome function and at the ricin protein itself.  Students individually complete a cumulative assignment of writing a letter back to Mom and Dad about how ricin has its effects. This case was designed for use in a second semester biochemistry course or a molecular biology course that incorporates the mechanism of transcription. Prerequisite knowledge includes a general understanding of the steps of translation and the ability to interpret data from agarose gels.

2:51 minute video about mechanics of transcription and translation 

3:32 minute video about transcription and translation of insulin

7 minute video; mash up of multiple cool animation videos - 0-1:20   supercoiling DNA to chromosomes 1:25- 1:40 cell division/mitosis 1:45-2:50  DNA replication  2:55-4:45   transcription  4:50-6:55  translation 7:00-7:47

1:40 video with transcript It might take practice to get to Carnegie Hall but scientists found that it takes a set of dozens of genes in the brain working together to make that practice pay off.

14 minute video using hot pocket analogy for the central dogma

Unprecedented multiple and extreme-level resistance is generated in mosquitoes found in the rice fields of Tiassalé in southern Côte d'Ivoire. A new study highlights the combination of stringently-replicated whole genome transcription profiling, in vivo transgenic gene expression and in vitro metabolism assays to identify and validate genes from the P450 detoxification enzyme superfamily which are highly expressed in the adult females from the area.

This "clicker case" tells the story of "Hannah," a baby girl adopted by two loving parents who grows up with an uncontrolled appetite and develops severe early-onset obesity. Students follow Hannah's story as she develops excessive eating early in life, which her health care team is unable to explain. A visit to obesity specialists finally reveals the underlying cause of Hannah's obsession with food: extremely low levels of circulating leptin, a hormone that regulates appetite and body weight. It is further discovered that Hannah's leptin deficiency is due to a mutation in the LEP gene. As the story unfolds, students first work on unit conversions and BMI calculations to practice quantitative skills as well as graph and data interpretation skills. Students then apply their knowledge of DNA transcription, translation, and protein structure to answer questions based on figures from a 2019 study on LEP mutations. The case is best suited for high school and lower-level undergraduate biology courses.

videos and animations for cellular processes

Carolina Biologica videos- How DNA is packaged Central Dogma Misconceptions in Genetics Strawberry Lab

video 2:47 Gene 'switches' are what really make humans tick

webpage tutorials with check for understanding

3:35 minute video trailer for protein synthesis

28 min video on DNA, RNA, protein

4 minute video introducing Central dogma

Collection of video animation/movies

Summary of research investigating purpose of introns.

article addresses student question, "Why do cells use uracil, when thymine is already available?"