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Lottie Peppers

Cell Division - Mitosis and Meiosis | ASU - Ask A Biologist - 0 views

  • Mitosis Cell DivisionMitosis is how somatic—or non-reproductive cells—divide. Somatic cells make up most of your body's tissues and organs, including skin, muscles, lungs, gut, and hair cells. Reproductive cells (like eggs) are not somatic cells.In mitosis, the important thing to remember is that the daughter cells each have the same chromosomes and DNA as the parent cell. The daughter cells from mitosis are called diploid cells. Diploid cells have two complete sets of chromosomes.  Since the daughter cells have exact copies of their parent cell's DNA, no genetic diversity is created through mitosis in normal healthy cells. 
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    Article summarizing cell division with time lapse cell division video of 30hours pro vs eukaryotic division.
Lottie Peppers

Resurrection - National Center for Case Study Teaching in Science - 0 views

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    This case study examines the molecular methods that were used to reverse engineer the 1918 influenza virus strain in order to try and solve the mystery of why it was so deadly. The story starts in the 1950s with the unsuccessful attempts to culture the influenza virus and follows scientists through to the turn of the century when cutting edge molecular tools enabled scientists to finally resurrect the 1918 virus through reverse genetics. The history and methods involved in resurrecting this deadly virus are reviewed in class with a PowerPoint presentation containing clicker questions (answered with a personal response system) and discussion questions (answered in small groups). This "clicker case" is suitable for high school biology and lower division undergraduate biology classes for non-majors. It could also be used in any lower division non-major class focused on human disease and the history of human disease.
Lottie Peppers

Disease Along the River: A Case Study and Cholera Outbreak Game - National Center for C... - 0 views

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    This case study centers on an active teaching game that simulates a cholera outbreak among five villages along a river, similar to the Haitian outbreak of 2010. By enacting the behaviors of fictional villagers, students learn how trade, travel, sanitation practices and geographic location contribute to the spread of diarrheal disease. Documenting various contamination events of village water supplies allows students to trace the progression of the disease and illustrates how adequate sanitation facilities provide protection against the bacteria Vibrio cholera. Originally designed for an undergraduate upper-division biology course focusing on the epidemiology of diseases, the simulation is also appropriate for microbiology and public health courses, as well as lower division undergraduate biology courses and high school. Biology or epidemiology components of the case study can be highlighted depending on the emphasis of the course being taught. The game can be completed within a 45- to 60-minute class period. Playing cards are available from the Supplemental Materials tab; detailed instructions are found in the teaching notes.
Lottie Peppers

Peripheral Nervous System: Crash Course A&P #12 - YouTube - 1 views

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    It is now time to meet the system that helps your crazy brain stay in touch with the outside world. We follow up last week's tour of the central nervous system with a look at your peripheral nervous system, its afferent and efferent divisions, how it processes information, the reflex arc, and what your brain has to say about pain. Table of Contents Peripheral Nervous System 0:38 Afferent and Efferent Divisions 5:42 Information and Responses to Pain 3:12 Five Steps of the Reflex Arc 4:35 Different Kinds of Reflexes 6:44 What the Brain Says About Pain 8:09
Lottie Peppers

How do cancer cells behave differently from healthy ones? - George Zaidan - YouTube - 0 views

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    How do cancer cells grow? How does chemotherapy fight cancer (and cause negative side effects)? The answers lie in cell division. George Zaidan explains how rapid cell division is cancer's "strength" -- and also its weakness.
Lottie Peppers

The simple math that explains why you may (or may not) get cancer | Science/AAAS | News - 0 views

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    In a paper this week in Science, Vogelstein and Cristian Tomasetti, who joined the biostatistics department at Hopkins in 2013, put forth a mathematical formula to explain the genesis of cancer. Here's how it works: Take the number of cells in an organ, identify what percentage of them are long-lived stem cells, and determine how many times the stem cells divide. With every division, there's a risk of a cancer-causing mutation in a daughter cell. Thus, Tomasetti and Vogelstein reasoned, the tissues that host the greatest number of stem cell divisions are those most vulnerable to cancer. When Tomasetti crunched the numbers and compared them with actual cancer statistics, he concluded that this theory explained two-thirds of all cancers.
Lottie Peppers

Antibiotic Resistance in a Russian Prison - National Center for Case Study Teaching in ... - 0 views

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    In this case study, students will have the opportunity to model the spread of tuberculosis and development of antibiotic resistance in a hypothetical prison environment. After reading a brief handout and viewing a short video, students play a simulation game by first identifying a group of prison inmates represented by index cards. The placement of the cards will influence how drug resistance spreads from one inmate to another. Using a dice roll to mimic random probability of infection and antibiotic misuse, students then track the development of resistance to four specific antibiotics, determined by selection of playing card suit. Opportunity for release or transfer on inmates from one facility to another introduces a further level of complexity, allowing students to study resistance spread. This activity was originally designed for a section of an upper-division biology course about antibiotic resistance, but it would also be appropriate for lower-division undergraduate and high school biology courses discussing antibiotic use.
Lottie Peppers

The Face of a Rare Genetic Disease - National Center for Case Study Teaching in Science... - 0 views

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    This case study is designed to teach basic concepts of genetics by focusing on a rare disease, pseudoxanthoma elasticum (PXE).  Chromosome 16 is the narrator at the beginning of the case and introduces students to genes, chromosomes and mutations. The focus then shifts to the patient and his mother as she finds out about her son's disease and her subsequent efforts to connect with patient advocacy groups for support. The case concludes with students watching a TED talk given by Sharon Terry, the real-life mother on whom this story is loosely based, so that students can connect on an emotional and human level with someone who has intimate experience as a parent of children with a rare genetic disease. The case is suitable for high school general biology classes, but it can also be used by biology major or non-major undergraduates in a lower-division biology class, or in any lower-division non-major class focused on human disease.
Lottie Peppers

NPS: Explore Nature» Air Resources Division-Students and Teachers:Acid Rain L... - 0 views

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    The National Park Service Air Resources Division in an effort to increase the public's awareness of air quality issues has developed a series of five activities for elementary and secondary schools. The activities are for grades six through eight and help teach students about Acid Rain. The lesson plan was prepared as a part of The Uplands Field Research Laboratory, Volunteer in Parks, and Interpretation of Science Project. Funding was provided by the Great Smoky Mountains Natural History Association.
Lottie Peppers

Meiosis | HHMI's BioInteractive - 0 views

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    Meiosis, the form of cell division unique to egg and sperm production, sets the stage for sex determination by creating sperm that carry either an X or a Y sex chromosome. But what is it about the X or Y that determines sex? Before a meiotic cell divides, its two sets of chromosomes come together and cross over, or swap, segments. The first animation shows normal crossing over, where the X and Y chromosomes exchange pieces only at their tips. The second animation shows a rare mistake in which the Y chromosome transfers a gene called SRY to the X chromosome, resulting in sex-reversed babies. Studies of sex-reversed individuals led researchers to identify the master switch for sex determination, the SRY gene, which tells a fetus to become a boy.
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    Meiosis, the form of cell division unique to egg and sperm production, sets the stage for sex determination by creating sperm that carry either an X or a Y sex chromosome. But what is it about the X or Y that determines sex? Before a meiotic cell divides, its two sets of chromosomes come together and cross over, or swap, segments. The first animation shows normal crossing over, where the X and Y chromosomes exchange pieces only at their tips. The second animation shows a rare mistake in which the Y chromosome transfers a gene called SRY to the X chromosome, resulting in sex-reversed babies. Studies of sex-reversed individuals led researchers to identify the master switch for sex determination, the SRY gene, which tells a fetus to become a boy.
Lottie Peppers

Reference Links for Key Numbers in Biology - 0 views

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    Reference page cellular facts: cell size, lenth, division, concentration, energy, diffusion, genomic information, and mutation rates.
Lottie Peppers

Synchronized Division - 0 views

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    groups of cells in the blastula are synchronized to divide at the same time through mitosis. Some of these cells will eventually give rise to the sand dollar's germ cells. Others will play important roles in various developmental processes, such as cell differentiation, the formation of the digestive system, and the development of the exoskeleton. Despite their different characteristics and roles, all of the sand dollar's cells (except for eggs or sperm) are genetically identical due to mitosis.
Lottie Peppers

Elephants: Large, Long-Living and Less Prone to Cancer - The New York Times - 0 views

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    In 1977, a University of Oxford statistician named Richard Peto pointed out a simple yet puzzling biological fact: We humans should have a lot more cancer than mice, but we don't. Dr. Peto's argument was beguilingly simple. Every time a cell divides, there's a small chance it will gain a mutation that speeds its growth. Cells that accumulate several of these mutations may become cancerous. The bigger an animal is, the more cells it has, and the longer an animal lives, the more times its cells divide. We humans undergo about 10,000 times as many cell divisions as mice - and thus should be far more likely to get cancer.
Lottie Peppers

Brain Workouts - National Center for Case Study Teaching in Science - 0 views

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    This directed case study follows two college roommates, Darrell and Anthony, who have just returned to school after winter vacation. They share that their ageing fathers are concerned about their declining faculties and are amused by their fathers' efforts to reverse the process.  Darrell's dad plays "brain games" on the computer while Anthony's father believes running will slow his memory decline. Intrigued, the roommates search through their biopsychology class notes to find out whether their fathers are correct. They review the topics of synaptic formation and plasticity, including axonal and dendritic development, and chemical factors in the brain that promote the survival and growth of neurons or stop the genetically programmed death of neurons. Based on research findings, students reading this case will decide whether Darrell and Anthony's fathers are correct in their assertions. The case is appropriate for a wide variety of courses including introductory anatomy or physiology, or for upper-division biopsychology, biology, or neuroscience courses.
Lottie Peppers

Anencephaly in Yakima - National Center for Case Study Teaching in Science - 0 views

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    This case study explores the recent (2010 - 2016) outbreak of neural tube defects, specifically anencephaly, in a rural three-county region of Washington state, particularly Yakima, WA. The case study focuses on the biological aspects of teratogens that may cause birth defects as well as epidemiological investigations of disease outbreaks. By the end of the case, students will have explored how our environment may have severe biological consequences on the human body during pregnancy and will have evaluated governmental and scientific investigations of a rare outbreak of birth defects. This clicker case study was developed for a non-majors biology course entitled "Human Development: Conception to Birth," although it could be taught in any introductory biology course for majors or non-majors during a unit on human reproductive biology or developmental biology. The case assumes that students have no prior knowledge of developmental biology or birth defects. The case study could also be adapted for upper-division courses by getting more in-depth on the specifics of teratogen mechanisms, the developmental biology and physiology of neural tube defects, or more complex epidemiological analyses.
Lottie Peppers

Hunting the Black Rhino - National Center for Case Study Teaching in Science - 0 views

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    This case study was developed to teach students the importance of understanding the behavior of wildlife, explore the difficulty in making management decisions when the public is invested in a species, and to help students develop critical thinking and public speaking skills. Students learn about the conservation status and behavior of the black rhinoceros by reading a primary literature article and answering a series of questions. They then listen to a Radiolab podcast that explores the moral dilemma of whether it is ethically appropriate to shoot an endangered rhinoceros if the purpose is to raise conservation funds. Students are assigned one of five positions and write essays to prepare for a town hall style debate in which they examine the pros and cons of such a decision. The Radiolab podcast is based on real events, and is also representative of many ethical dilemmas that wildlife managers regularly face. This case study is appropriate for several upper division biology courses.
Lottie Peppers

Explore Biology | Regents Biology Teaching & Learning Resources - 0 views

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    Well organized teacher site- AP Biology Web site for Ms. Foglia's Regents Biology (10th grade Living Environment) course at Division Avenue High School, Levittown. It will be a busy year and I will use this Web site to help you to do the best you can. All paperwork, labs, and resources used or mentioned in class will be posted here.
Lottie Peppers

Mitotic Cell Division Hoop Shoot Out Basketball Game (ID: 127) - 0 views

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    Basketball mitosis review game
Lottie Peppers

Epigenetics - It's not just genes that make us | British Society for Cell Biology - 0 views

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    Quick look: In its modern sense, epigenetics is the term used to describe inheritance by mechanisms other than through the DNA sequence of genes. It can apply to characteristics passed from a cell to its daughter cells in cell division and to traits of a whole organism. It works through chemical tags added to chromosomes that in effect switch genes on or off.
Lottie Peppers

From Cow Juice to a Billion Dollar Drug, With Some Breakthroughs in Between - National ... - 0 views

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    Before the discovery of insulin in 1921, being diagnosed with Type 1 diabetes was a death sentence. Despite the successful management of diabetes with purified animal insulin, potentially severe side effects were abundant, and alternative ways to produce insulin were needed. This case study guides students through the history of using insulin to treat diabetes, focusing on the development of recombinant DNA technology and the world's first bioengineered drug, recombinant human insulin, which is now used worldwide to treat diabetes. Through the course of this case, students consider the central dogma of molecular biology, the development of recombinant DNA technology, drug design, the importance of recombinant proteins to our society, and the ethical analysis and debates that occur as a result of some scientific discoveries. This case was developed as an introduction to an upper-division biotechnology course focusing on recombinant protein design and production, but could also be used in molecular biology, biochemistry, or introductory biology courses to highlight recombinant DNA and biotechnology.
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