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Another case is ready for you: "East Meets West: An Infectious Disease Case" by Harry M. Zollars, Catherine D. Santanello, and Marcelo J. Nieto, Department of Pharmaceutical Sciences, Southern IL University Edwardsville.   Ying is sick and is progressively getting worse. His parents' clashing views on Eastern and Western medicine prevent them from agreeing on a course of treatment. As the case unfolds, students follow the progression of their son's illness. After a physician is finally seen and the results of tests are evident, students should be able to narrow the list of possible etiological agents and suggest a potential treatment. In addition, the students should integrate the different health beliefs into the final treatment as well as the aspects of patient counseling. The case works well as an interrupted case that can be assigned to individual students or student teams. This case is appropriate for graduate courses with a component in health care, therapeutics, medicinal chemistry, medicinal plants, microbiology, epidemiology, or cultural competency. Instructors can choose to focus only on the medical components of the case or incorporate the cultural and ethical aspects, depending on course goals and subject area.

Stem Cell Overview Article with embedded Video 7:53 Discusses gene expression/differentiation 2 minute segments -Pluripotent stem cells in early embryo CDX2 OCT3/4, Inner cell mass start- 1:50 - Characteristics of Stem Cells: differentiation, abilities of stem cells,  1:55- 3:17 - Stem Cells in the Adult Body: red blood cell hematopoetic stem cells, differentiation, small intestine crypts,  3:20-5:35 - Embryonic Stem Cells in Culture: ES pluripotent cells ES cells, treat to neural lineages, culture conditions, study differentiate into lineages 5:40- 7:53

Dubilier is hardly alone in her plight. A heaping teaspoon of soil or a shot of ocean water may contain as many as one million bacterial species. Many of them are potential gold mines of chemicals and metabolites with medicinal, engineering, and energy applications. But when researchers have tried to culture these microbes in the lab, only a minority of cells form colonies. Clearly, nutrients, a carbon source, and time are usually not enough to coax bacteria isolated from the wild to grow in a laboratory setting. So what's the missing ingredient?

The scientific progress that has made it possible to dream of a future in which faulty organs could be regrown from stem cells also holds potential as an ethical and greener source for meat. So say scientists who suggest that every town or village could one day have its very own small-scale, cultured meat factory.

" A brief visual task can predict IQ, according to a new study. This surprisingly simple exercise measures the brain's unconscious ability to filter out visual movement. The study shows that individuals whose brains are better at automatically suppressing background motion perform better on standard measures of intelligence. The test is the first purely sensory assessment to be strongly correlated with IQ and may provide a non-verbal and culturally unbiased tool for scientists seeking to understand neural processes associated with general intelligence."

It concludes that the so-called stimulus-triggered acquisition of pluripotency (STAP) stem cells, as well as the chimeric mice and teratomas supposedly derived from those cells, "all originated in cultures contaminated with (embryonic stem) cells, a fact that refutes all of the main conclusions of the two papers" that reported the the supposed breakthrough method of reprogramming adult cells. Those two papers, an article and a letter, appeared online in Nature on 29 January.

Curriculum materials for the following topics: HeLa Cells & HPV Genes: Immortality & Cancer, which reviews basic cell biology, tissue culture, and human subjects research in the context of privacy, rights, and compensation. Link: http://www.stemcellcurriculum.org/hela-cells-hpv-genes-immortality-cancer.html · Eggs & Blood: Gifts & Commodities, which addresses the value placed on some bodily tissues/cells and not on others. Link: http://www.stemcellcurriculum.org/eggs-and-blood.html · Disease, Disability, & Immortality: Hope & Hype, which explores the natural physical and cognitive variability in the human population and questions the goal of a "cure" in biomedical research. Link: http://www.stemcellcurriculum.org/disease-disability-immortality-hope-hype.html · Stem Cells & Policy: Values & Religion, which analyzes how policy is shaped in pluralistic societies that require tolerance of different points of view. Link: http://www.stemcellcurriculum.org/stem-cells-policy-values-and-religion.html

This case study examines the molecular methods that were used to reverse engineer the 1918 influenza virus strain in order to try and solve the mystery of why it was so deadly. The story starts in the 1950s with the unsuccessful attempts to culture the influenza virus and follows scientists through to the turn of the century when cutting edge molecular tools enabled scientists to finally resurrect the 1918 virus through reverse genetics. The history and methods involved in resurrecting this deadly virus are reviewed in class with a PowerPoint presentation containing clicker questions (answered with a personal response system) and discussion questions (answered in small groups). This "clicker case" is suitable for high school biology and lower division undergraduate biology classes for non-majors. It could also be used in any lower division non-major class focused on human disease and the history of human disease.

The club, which has about 20 members, is researching the culture and regrowth of methanotrophic bacteria, using a wide variety of experiments and individual projects. The students meet every Thursday with their advisor, Michael Ralph, and they also work during their own time.

Promotes accurate understanding and comprehensive teaching of evolutionary theory for a wide audience Explores the practical applications of evolutionary principles in daily life and the impact of evolutionary theory on culture and society throughout history Offers teaching tools such as unit and lesson plans and classroom activities, as well as additional online content such as podcasts and powerpoint presentations

We, and the West Turkana Archaeological Project which we co-lead, had discovered the earliest stone artifacts yet found, dating to 3.3 million years ago. The discovery of the site, named Lomekwi 3, instantly pushed back the beginning of the archaeological record by 700,000 years. That's over a quarter of humanity's previously known material cultural history.

Emerging diseases and potential pandemics make the news nearly every year. Students (and everyone else) may wonder where new infectious diseases come from, how scientists assess the risk of a pandemic, and how we might go about preventing one. This case study uses a PowerPoint presentation to explore these questions by focusing on HIV, a pandemic that began as an emerging disease. The storyline progresses backwards through time as scientists attempt to unravel the origins of a new, mysterious plague. Much of the case relies on audio excerpts from an episode produced by Radiolab, an acclaimed radio show that explores a variety of topics in science and culture (www. radiolab.org). Students use graphics, animations, and sound clips presented in the PowerPoint slides to discuss several sets of questions. The case is suitable for a wide range of high school and college introductory biology courses, as well as undergraduate microbiology, ethics, and public health courses.

Decades ago, few pediatricians had heard of autism. In 1975, 1 in 5,000 kids was estimated to have it. Today, 1 in 68 is on the autism spectrum. What caused this steep rise? Steve Silberman points to "a perfect storm of autism awareness" - a pair of doctors with an accepting view, an unexpected pop culture moment and a new clinical test. But to really understand, we have to go back further to an Austrian doctor by the name of Hans Asperger, who published a pioneering paper in 1944. Because it was buried in time, autism has been shrouded in misunderstanding ever since. (This talk was part of a TED2015 session curated by Pop-Up Magazine: popupmagazine.com or @popupmag on Twitter.)

This interactive case discussion was created to emphasize the clinical relevance of population genetics, but is also a suitable resource for teaching the basic principles of population genetics while relating them to human genetic variation. Our understanding of human genetic variation has deepened over the past decade due to fine-scale genome mapping. Applying this knowledge to the evaluation of ancestry-based genetic testing strategies, such as direct-to-consumer genetic testing, is an important component of the practice of culturally-competent medicine and a relevant way to teach the foundations of population genetics, including Hardy-Weinberg equilibrium.

The treatment used olfactory ensheathing cells (OECs) - specialist cells that form part of the sense of smell. OECs act as pathway cells that enable nerve fibres in the olfactory system to be continually renewed. In the first of two operations, surgeons removed one of the patient's olfactory bulbs and grew the cells in culture. Two weeks later they transplanted the OECs into the spinal cord, which had been cut through in the knife attack apart from a thin strip of scar tissue on the right. They had just a drop of material to work with - about 500,000 cells.

Where does bread get its fluffiness? Swiss cheese its holes? And what makes vinegar so sour? These foods may taste completely different, but all of these phenomena come from microorganisms chowing down on sugar and belching up some culinary byproducts. Erez Garty shows how your kitchen functions as a sort of biotechnology lab, manned by microorganisms that culture your cuisine.

Gene flow is the transfer of genetic material between separate populations. Many organisms are divided into separate populations that have restricted contact with each other, possibly leading to reproductive isolation. Many things can fragment a species into a collection of isolated populations. For example, a treacherous mountain pass may cut off one herd of mountain goats from another. In human beings, cultural differences as well as geographic separation maintain unique populations: It is more likely that a person will marry and have children with someone who lives nearby and speaks the same language.

4:51 video What's tasty, abundant and high in protein? Bugs! Although less common outside the tropics, entomophagy, the practice of eating bugs, was once extremely widespread throughout cultures. You may feel icky about munching on insects, but they feed about 2 billion people each day (Mmm, fried tarantulas). They also hold promise for food security and the environment. Emma Bryce makes a compelling case for dining on bugs.

This interdisciplinary case study uses the format of a progressive disclosure to explore certain advances in biotechnology and evaluate them within the framework of societal needs, concerns and pressures.  When faced with a heart valve transplant, a high school student and her mother must decide between multiple approaches, some current and others emergent. Highlighted in this case study are the topics of xenotransplantation, 3D bioprinting and the mature minor rule. The case includes a role-playing, public hearing activity that can be used to explore many aspects at the interface of technology and culture: religious rights, parental rights, public health care policy and safety, animal rights, economic issues of organ marketing, and psychological issues of body image.  This case study was originally designed for first year collegiate classes (introduction to biology, introduction to psychology) but is also applicable to AP high school. The flexible nature of the case also allows for expansion of several aspects for advanced classes across multiple disciplines.

Hilary Brown is a PhD student, working in the infection genomics group at the Wellcome Trust Sanger Institute. In this film he describes how to work safely in the lab with bacteria from the human gut including culturing them on agar plates and extracting the DNA for genome sequencing. The infection genomics programme uses a variety of different research approaches to study the biology and evolution of disease-causing organisms such as viruses, bacteria and parasites and understand how they cause disease in humans and other animals.