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In this interrupted case study developed for use in a flipped classroom, students read about a picnic that takes place in autumn during the peak of fall color and along the way learn about light absorption by photosynthetic pigments, why leaves turn color in the fall, atmospheric CO2 concentrations and their effect on photosynthesis, and the C3, C4, and CAM photosynthetic pathways. The case is designed to provide introductory biology students with a basic understanding of photosynthetic pathways and how environmental factors affect plants using these pathways. The activity could also be used in an advanced high school biology course covering photosynthesis. The case includes several short videos that students watch as homework before coming to class so that they are prepared to work together in class in small groups to answer the case questions.

This flipped case study begins with a video in which a student reveals a family member's diagnosis with breast cancer and then considers the whirlwind of questions that arise in such a situation. Students are asked to relate to the main character and identify what questions they would have and what resources they could consult to seek information.  This sets the context for students to use websites and videos to investigate the nature of cancer, its causes, and progression. Students then learn about the major methods of cancer treatment (surgery, radiation therapy, and chemotherapy), how they work, and the limitations and side effects of each. The case concludes by addressing the claim of one of the characters that there is a conspiracy to hide a cure for cancer. The case would be implemented near the middle of a high school, non-majors, or introductory biology course after discussion of basic cell biology and the cell cycle.

This case study introduces students to the "Red Queen Hypothesis." The hypothesis states that when two species compete for a limited resource or exist in a predator-prey relationship, in order for the antagonists to remain in relative population equilibrium, there must be ongoing and reciprocal adaptation on each side. If one species fails to adapt, it may quickly face extinction. Students are introduced to the Red Queen Hypothesis through an excerpt from Lewis Carroll's novel, Through the Looking Glass, in which Alice meets the Red Queen. They then review experiments from the research literature to evaluate the validity of the hypothesis in extant populations.  Students culminate their learning by contrasting their knowledge of the Red Queen Hypothesis to Darwinian evolutionary theory based on a passage from On the Origin of Species.  Students then craft a letter to Darwin helping to explain his "wedge" theory, a notion he originally developed but removed from later iterations of his book due to a lack of experimental evidence. Originally developed for advanced high school biology students, the case also may be used in a college-level introductory course on evolutionary biology.

This case study is designed to teach basic concepts of genetics by focusing on a rare disease, pseudoxanthoma elasticum (PXE).  Chromosome 16 is the narrator at the beginning of the case and introduces students to genes, chromosomes and mutations. The focus then shifts to the patient and his mother as she finds out about her son's disease and her subsequent efforts to connect with patient advocacy groups for support. The case concludes with students watching a TED talk given by Sharon Terry, the real-life mother on whom this story is loosely based, so that students can connect on an emotional and human level with someone who has intimate experience as a parent of children with a rare genetic disease. The case is suitable for high school general biology classes, but it can also be used by biology major or non-major undergraduates in a lower-division biology class, or in any lower-division non-major class focused on human disease.

The life science/biology course is divided into 12 instructional segments grouped into four sections. In the first section, From Molecules to Organisms: Structures and Processes, students develop models of how molecules combine to build cells and organisms (IS1 [Structure and Function]; IS2 [Growth and Development of Organisms]; IS3 [Organization for Matter and Energy Flow in Organisms]). In the second section, Ecosystems: Interactions, Energy, and Dynamics, students zoom out to the macroscopic scale to show how organisms interact (IS4 [Interdependent Relationships in Ecosystems]; IS5 [Cycles of Matter and Energy Transfer in Ecosystems]; IS6 [Ecosystem Dynamics, Functioning, and Resilience]; IS7 [Social Interactions and Group Behavior]). Students return to the role that DNA plays in inheritance during the third section, Heredity: Inheritance and Variation of Traits (IS8 [Inheritance of Traits]; IS9 [Variation of Traits]). The class ends tying together interactions at all these scales by explaining evolution and natural selection in Biological Evolution: Unity and Diversity (IS10 [Evidence of Common Ancestry and Diversity]; IS11 [Natural Selection]; IS12 [Adaptation and Biodiversity]). A vignette in IS12 illustrates the level of three-dimensional understanding students are expected to exhibit as a capstone of the course.

"inquiryHub is a research practice partnership engaged in research and development of materials, tools, and processes to promote equitable student learning of STEM. inquiryHub Biology is an open access, deeply digital high school biology curriculum designed to support the Next Generation Science Standards.  "

This "clicker case" tells the story of "Hannah," a baby girl adopted by two loving parents who grows up with an uncontrolled appetite and develops severe early-onset obesity. Students follow Hannah's story as she develops excessive eating early in life, which her health care team is unable to explain. A visit to obesity specialists finally reveals the underlying cause of Hannah's obsession with food: extremely low levels of circulating leptin, a hormone that regulates appetite and body weight. It is further discovered that Hannah's leptin deficiency is due to a mutation in the LEP gene. As the story unfolds, students first work on unit conversions and BMI calculations to practice quantitative skills as well as graph and data interpretation skills. Students then apply their knowledge of DNA transcription, translation, and protein structure to answer questions based on figures from a 2019 study on LEP mutations. The case is best suited for high school and lower-level undergraduate biology courses.

An ongoing commitment to diversity, equity, and inclusion (DEI) work will help you build the foundations of belonging for every student. But DEI work alone is not enough. Let's go back to your students. Are your lessons designed in alignment with what we know from cognitive science about how the human brain learns? What does the practice work you assign look like? What study strategies do you teach students to use? How is metacognition built? Does the feedback you give students help or hurt? What does homework look like?

Hands on lab activities

One common virus takes a sneaky route to success. It doesn't kill its leafy hosts. Instead, it makes infected plants smell more attractive to bees. That ensures this germ will have a new generation of the plants to host it in the future.

data sets for analysis

Student scientist journal

Lesson plans from a 5 day summer workshop through the CDC

Introduction to the major concepts related to emerging and re-emerging infectious diseases, and impact on society.

"Bioethics modules serve as a guide for teachers who want to incorporate an in-depth analysis of bioethical issues and debates into their life sciences, social sciences, public policy, or theology courses. They provide lesson plans that teachers can use to lead classes and discussions on topics in bioethics. Within each module, you will find background information, readings, suggested classroom procedures and activities, and links for additional information and resources."

Post the link to the Science News article "Life on Earth may have begun in hostile hot springs" to your virtual classroom. Ask students to read the article for homework and prepare for online class by answering the first question. Before the class meets, provide the students with the links to all articles they will need for class. Class discussion can be conducted via Zoom; the research and recipe-building components can be conducted in breakout rooms.

Weaving Social Justice Into Science Instruction Shedding light on inequity in science fields bolsters students' critical thinking skills and sense of self-efficacy in science. A free curriculum helps teachers get started.