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he Department of Energy (DOE) seeks input from the public related to improving the manufacturing process for both marine and hydrokinetic (MHK) and hydropower technologies. An emphasis on design for manufacturing could transition a nascent MHK industry from its current focus on performance prototypes towards manufacturing cost competitive production units. Advanced materials and manufacturing processes for hydropower turbines could result in cost reduction across the entire power plant that will have significant impact on the levelized cost of energy (LCOE) of hydropower. Investment in materials and manufacturing will drive an increase of U.S. domestic manufacturing content in clean energy technologies. DOE is seeking to improve these areas and is requesting information to identify

The National Institutes of Health (NIH) Office of the Associate Director for Data Science (ADDS) announces a collaboration with the Wellcome Trust (WT) and the Howard Hughes Medical Institute (HHMI) to launch the ``Open Science Prize'' (the ``Challenge'') to encourage and support the prototyping and development of services, tools and/or platforms that enable open content--including publications, datasets, code and other research outputs--to be discovered, accessed and re-used in ways that will advance research, spark innovation, and generate new societal benefits. The Challenge is necessary to accelerate the field of ``open'' biomedical research beyond what current funding mechanisms can achieve.

The Technology Validation and Start-Up Fund (the "Program") provides grants to transition technology from Ohio research institutions into the marketplace through Ohio start-up companies. Ohio research institutions may apply for funding for validation (e.g. viability testing, prototyping, etc.) of their unlicensed technologies. Ohio start-up companies may apply for funding to advance towards commercialization a technology they intend to license from an Ohio research institution.

The Division of Materials Research (DMR), the Division of Mathematical Sciences (DMS), the Division of Electrical, Communications and Cyber Systems (ECCS), and the Office of Advanced Cyberinfrastructure (OAC) seek to rapidly accelerate quantum materials design, synthesis, characterization, and translation of fundamental materials engineering and information research for quantum devices, systems, and networks. The new program of Enabling Quantum Leap: Convergent Accelerated Discovery Foundries for Quantum Materials Science, Engineering, and Information (Q-AMASE-i) aims to support these goals by establishing Foundries with mid-scale infrastructure for rapid prototyping and development of quantum materials and devices. The new materials, devices, tools and methods developed by Q-AMASE-i will be shared with the science and engineering communities through a Foundry-operated network. Technology transfer of Foundry activities will be enabled by close cooperation with industrial partners.

The Partnerships for Innovation (PFI) Program within the Division of Industrial Innovation and Partnerships (IIP) offers researchers from all disciplines of science and engineering funded by NSF the opportunity to perform translational research and technology development, catalyze partnerships and accelerate the transition of discoveries from the laboratory to the marketplace for societal benefit. PFI has five broad goals, as set forth by the American Innovation and Competitiveness Act of 2017 ("the Act", S.3084 - 114th Congress; Sec. 602. Translational Research Grants): (1) identifying and supporting NSF-sponsored research and technologies that have the potential for accelerated commercialization; (2) supporting prior or current NSF-sponsored investigators, institutions of higher education, and non-profit organizations that partner with an institution of higher education in undertaking proof-of-concept work, including the development of technology prototypes that are derived from NSF-sponsored research and have potential market value; (3) promoting sustainable partnerships between NSF-funded institutions, industry, and other organizations within academia and the private sector with the purpose of accelerating the transfer of technology; (4) developing multi-disciplinary innovation ecosystems which involve and are responsive to the specific needs of academia and industry; (5) providing professional development, mentoring, and advice in entrepreneurship, project management, and technology and business development to innovators.

PFI has five broad goals, as set forth by the American Innovation and Competitiveness Act of 2017 ("the Act", S.3084 - 114th Congress; Sec. 602. Translational Research Grants): (1) identifying and supporting NSF-sponsored research and technologies that have the potential for accelerated commercialization; (2) supporting prior or current NSF-sponsored investigators, institutions of higher education, and non-profit organizations that partner with an institution of higher education in undertaking proof-of-concept work, including the development of technology prototypes that are derived from NSF-sponsored research and have potential market value; (3) promoting sustainable partnerships between NSF-funded institutions, industry, and other organizations within academia and the private sector with the purpose of accelerating the transfer of technology; (4) developing multi-disciplinary innovation ecosystems which involve and are responsive to the specific needs of academia and industry; (5) providing professional development, mentoring, and advice in entrepreneurship, project management, and technology and business development to innovators.

The Defense Advanced Research Projects Agency (DARPA) is issuing an Artificial Intelligence Exploration (AIE) Opportunity, inviting submissions of innovative basic or applied research concepts in the technical domain of automated knowledge discovery, curation, and application. This AIE Opportunity is being issued under the Program Announcement for AIE, DARPA-PA-18-02. All proposals in response to the Automating Scientific Knowledge Extraction (ASKE) opportunity, as described herein, will be submitted to DARPA-PA-18-02-01. If selected, it will result in an award of an Other Transaction (OT) for Prototype agreement that will not exceed $1,000,000.

The overall goal of the Three Dimensional Monolithic System-on-a-Chip (3DSoC) program is to develop 3D monolithic technology that will enable > 50X improvement in SOC digital performance at power. 3DSOC aims to drive research in process, design tools, and new compute architectures for future designs while utilizing U.S. fabrication capabilities. The goal of the Foundations Required for Novel Compute (FRANC) program is to define the foundations required for assessing and establishing the proof of principle for beyond von Neumann compute architectures. FRANC will seek to demonstrate prototypes that quantify the benefits of such new computing architectures.

NCATS plans to support the research, development and testing of up to three biomedical reasoning tool prototypes for the Biomedical Data Translator for an estimated $1,000,000 total costs each. NCATS is utilizing a three-step application process (challenge-concept-proposal) for this expedited program. The duration of each award will be less than one year. All awardees will be expected to collaborate and cooperate with NCATS staff, one another and potentially other contributors to the overall program to maximize the exploration of the potential capabilities of Translator and to understand technical feasibility and challenges of having multiple groups build a single resource. All U.S. and foreign organizations and U.S. citizens are eligible to apply. This funding opportunity is open to U.S. and foreign organizations, including academic institutions and commercial entities; subcontracts are allowed. U.S. citizens may also apply as individuals and may be direct recipients of an award. Non-citizen individuals residing in the U.S. or foreign country not affiliated with either a U.S. or foreign organization are not eligible to be direct recipients of an award. Successful completion of the application process will require applicants to have specific skills related to translational research and software development. Applicants need to demonstrate technical skills, including familiarity with web communication protocols, a variety of programming languages and software stack, and general algorithmic techniques in the areas of artificial intelligence, machine learning, and knowledge engineering, as well as problem solving skills, especially creativity and persistence. Applicants familiar with languages and packages most useful for solving different tasks, the entire challenge process may take between 2 and 8 hours to complete.

The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U01) applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this FOA focuses on early-stage development from prototyping to hardening and adaptation. Early-stage development is defined for the purpose of this FOA as the initial development or the significant modification of existing tools for new applications. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research field.

The Partnerships for Innovation (PFI) Program within the Division of Industrial Innovation and Partnerships (IIP) offers researchers from all disciplines of science and engineering funded by NSF the opportunity to perform translational research and technology development, catalyze partnerships and accelerate the transition of discoveries from the laboratory to the marketplace for societal benefit. PFI has five broad goals, as set forth by the American Innovation and Competitiveness Act of 2017 ("the Act", S.3084 - 114th Congress; Sec. 602. Translational Research Grants): (1) identifying and supporting NSF-sponsored research and technologies that have the potential for accelerated commercialization; (2) supporting prior or current NSF-sponsored investigators, institutions of higher education, and non-profit organizations that partner with an institution of higher education in undertaking proof-of-concept work, including the development of technology prototypes that are derived from NSF-sponsored research and have potential market value; (3) promoting sustainable partnerships between NSF-funded institutions, industry, and other organizations within academia and the private sector with the purpose of accelerating the transfer of technology; (4) developing multi-disciplinary innovation ecosystems which involve and are responsive to the specific needs of academia and industry; (5) providing professional development, mentoring, and advice in entrepreneurship, project management, and technology and business development to innovators.

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) and VentureWell have come together to support and expand DEBUT, a competition that recognizes undergraduate excellence in biomedical design and innovation. DEBUT challenges teams of students in undergraduate biomedical education to solve real-world problems in healthcare. Prizes of up to $20,000 will be awarded. Strong DEBUT submissions will demonstrate a mastery of analytical and design skills and capabilities; the ability to manage the product development process; the ability to work effectively in teams; and technical communication skills. Submissions will be judged on the following criteria: Significance of the problem being addressed Impact of the proposed solution on potential users and clinical care Innovative design Working prototype Additional prizes will be awarded to entries that also demonstrate: Market potential and economic feasibility Patentability

he intent of this solicitation is to request proposals from organizations willing to serve as service providers (SPs) within the NSF Innovative High-Performance Computing (HPC) program to provide advanced cyberinfrastructure (CI) capabilities and/or services in production operations to support the full range of computational- and data-intensive research across all of science and engineering (S&E). The current solicitation is intended to complement previous NSF investments in advanced computational infrastructure by provisioning resources, broadly defined in this solicitation to include systems and/or services, in two categories: Category I, Capacity Systems: production computational resources maximizing the capacity provided to support the broad range of computation and data analytics needs in S&E research; and Category II, Innovative Prototypes/Testbeds: innovative forward-looking capabilities deploying novel technologies, architectures, usage modes, etc., and exploring new target applications, methods, and paradigms for S&E discoveries.

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) and VentureWell have come together to support and expand DEBUT, a competition that recognizes undergraduate excellence in biomedical design and innovation. DEBUT challenges teams of students in undergraduate biomedical education to solve real world problems in healthcare. Prizes of up to $20,000 will be awarded, with a total prize purse of $80,000. Strong DEBUT submissions will demonstrate a mastery of analytical and design skills and capabilities; the ability to manage the product development process; the ability to work effectively in teams; and technical communication skills. Submissions will be judged on the following criteria: Significance of the problem being addressed Impact of proposed solution on potential users and clinical care Innovative design Working prototype

The intent of this solicitation is to request proposals from organizations willing to serve as service providers (SPs) within the NSF Innovative High-Performance Computing (HPC) program to provide advanced cyberinfrastructure (CI) capabilities and/or services in production operations to support the full range of computational- and data-intensive research across all of science and engineering (S&E). The current solicitation is intended to complement previous NSF investments in advanced computational infrastructure by provisioning resources, broadly defined in this solicitation to include systems and/or services, in two categories: Category I, Capacity Systems: production computational resources maximizing the capacity provided to support the broad range of computation and data analytics needs in S&E research; and Category II, Innovative Prototypes/Testbeds: innovative forward-looking capabilities deploying novel technologies, architectures, usage modes, etc., and exploring new target applications, methods, and paradigms for S&E discoveries

The Office of Naval Research (ONR) is interested in receiving proposals for developing innovative science and technology to enhance training systems for the United States Marine Corps (USMC). The program's goal is to create a robust and efficient enterprise capability that allows the integration and interoperability of legacy, current, and future Marine Corps training information technology assets to enhance warfighter capability. Future Integrated Training Environment (FITE) has been approved as a new five year research opportunity under the Capable Manpower Pillar (CMP) Future Naval Capabilities (FNC) program. FITE is specifically focused on developing science and technology prototype capabilities to support the integration of Air and Ground Live, Virtual, and Constructive (LVC) training simulation capabilities.

The Air Force Research Laboratory (AFRL) Space Vehicle Directorate (RV) is interested in receiving proposals from all offerors to advance state of the art technology and scientific knowledge supporting all aspects of space systems including payload adapters, on-orbit systems, communications links, ground systems, and user equipment. Efforts will include basic and advanced research, advanced component and technology development, prototyping, and system development and demonstration and will span the range from concept and laboratory experimentation to testing/demonstration in a relevant environment. Specific tasks include design, development, analysis, fabrication, integration, characterization, testing/experimentation, and demonstration of hardware and software products.

The goal of the Rapid Innovation Fund is to facilitate the rapid insertion of innovative technologies into military systems or programs that meet critical national security needs. The DoD seeks mature prototypes for final development, testing, evaluation, and integration. Those selected for award may receive up to $3 million in Rapid Innovation Funding and will have up to two years to perform the work. There is a source selection preference for technologies from small businesses. There are two phases in the source selection process: White paper submission and proposal submission. Proposal submissions are by invitation only.

This Broad Agency Announcement (BAA) with procurement instrument identification number HQ0034-17-BAA-RIF-0001 constitutes the solicitation of offers for research and development for the Rapid Innovation Fund. The goal of the Rapid Innovation Fund is to facilitate the rapid insertion of innovative technologies into military systems or programs that meet critical national security needs. The DoD seeks mature prototypes for final development, testing, evaluation, and integration. Those selected for award may receive up to $3 million in Rapid Innovation Funding and will have up to two years to perform the work. There is a source selection preference for technologies from small businesses. There are two phases in the source selection process: White paper submission and proposal submission. Proposal submissions are by invitation only. All responsible firms and academic institutions capable of satisfying the Government's needs may submit a White Paper under this BAA. Historically Black Colleges and Universities (HBCUs) and Minority Institutions (MIs) are encouraged to submit White Papers and/or participate in teaming arrangements in submitting White Papers; however, no portion of this announcement will be set aside for HBCU and MI participation.

The HPEM Modeling & Effects research and development effort consists of the following areas: understanding the connectivity of infrastructure and mobile targets; understanding the phenomenology of front door effects; developing a predictive effects model; developing a theoretical and empirical basis for HPEM effects ranging from the basic circuit level to the system level effects; empirical effects testing on operational targets as a function of frequency, pulsed duration, and power of the incident HPEM pulse; battle damage assessment; rapid modeling of HPEM system sources and components; improving particle-in-cell code (PIC) capabilities; first principles materials modeling; improving models for electron emission, gas desorption to enhance the predictive capability of virtual prototyping; and developing electromagnetic (EM) algorithms to propagate radio frequency (RF) from platform-specific high power RF systems to targets to assess the performance measures of effective HPEM sources. Sound software engineering and development principles must be employed for all developed software and documentation. Robust software testing, validation, and verification are critical to software development efforts. As appropriate, software must scale to large simulation sizes and be portable to massively parallel computer architecture.