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The Engineering of Biomedical Systems (EBMS)program is part of the Engineering Biology and Health cluster, which also includes 1) Biophotonics; 2) Biosensing; 3) Cellular and Biochemical Engineering; and 4) Disability and Rehabilitation Engineering. The goal of theEBMS program is to provide research opportunities for creating discovery-level and transformative projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term.EBMS projects must be at the interface of engineering and biomedical sciences. They are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. The project must include objectives that advance both engineering and biomedical sciences. EMBS projects should focus on high-impact, transformative methods and technologies -- especially those that potentially will have a broad impact on biomedical challenges. Projects may include: methods, models, and enabling tools applied to understand or control living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term. TheEBMS programsupports fundamental and transformative research in the following areas of biomedical engineering:

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) DEBUT Challenge is open to teams of undergraduate students working on projects that develop innovative solutions to unmet health and clinical problems. Entries are solicited in one of the following categories: *   Diagnostic Devices/Methods *   Therapeutic Devices/Methods *   Technology to Aid Underserved Populations and Individuals with Disabilities NIBIB's mission is to improve health by leading the development and accelerating the application of biomedical technologies.  The goals of the challenge are 1) to provide undergraduate students valuable experiences such as working in teams, identifying unmet clinical needs, and designing, building and debugging solutions for such open-ended problems; 2) to generate novel, innovative tools to improve healthcare, consistent with NIBIB's purpose to support research, training, the dissemination of health information, and other programs with respect to biomedical imaging and engineering and associated technologies and modalities with biomedical applications; and 3) to highlight and acknowledge the contributions and accomplishments of undergraduate students.

TheEngineering of Biomedical Systems program is part of the Engineering Biology and Health cluster, which also includes: 1) the Biophotonics program; 2) the Biosensing program; 3) the Cellular and Biochemical Engineering program; and 4) the Disability and Rehabilitation Engineering program. The goal of theEngineering of Biomedical Systems (EBMS) program is to provide opportunities for creating fundamental and transformative research projects that integrate engineering and life sciences to solve biomedical problems and serve humanity in the long term. Projects are expected to use an engineering framework (for example, design or modeling) that supports increased understanding of physiological or pathophysiological processes. Projects must include objectives that advance both engineering and biomedical sciences. Projects may include: methods, models, and enabling tools applied to understand or control living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; or new approaches to the design of systems that include both living and non-living components for eventual medical use in the long term.

This initiative will support projects that focus solely on development of technologies with the potential to enable biomedical research. Projects should be justified in terms of potential biomedical impact, but should not include any application to specific biomedical research questions. Proof of principle for the technology will have already been shown, but there will still be significant fundamental technical challenges. Applications should include preliminary data. The products of this research will be functioning prototype instruments, methods, synthetic approaches, etc., characterized adequately to be ready for first application to the type of biomedical research questions that provided the rationale for their development.

The mission of the Biomedical Engineering (BME) program is to provide opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life science principles in solving biomedical problems that serve humanity in the long-term.  The Biomedical Engineering (BME) program supports fundamental research in the following BME themes: Neural engineering (brain science, computational neuroscience, brain-computer interface, neurotech, cognitive engineering) Cellular biomechanics (motion, deformation, and forces in biological systems; how mechanical forces alter cell growth, differentiation, movement, signal transduction, transport, cell adhesion, cell cytoskeleton dynamics, cell-cell and cell-ECM interactions; genetically engineered stem cell differentiation with long-term impact in tissue repair and regenerative medicine) The BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences.  The projects should focus on high impact transforming methods and technologies. The project should include methods, models and tools of understanding and controlling of living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and new novel methods of reducing health care costs through new technologies. The projects should emphasize the advancement of fundamental engineering knowledge, possibly leading to the development of new methods and technologies in the long-term; and highlight multi-disciplinary nature, integrating engineering and the sciences. The long-term impact of the projects can be related to disease diagnosis and/or treatment, improved health care delivery, or product development.

The mission of the Biomedical Engineering (BME) program is to provide opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life science principles in solving biomedical problems that serve humanity in the long-term.  The Biomedical Engineering (BME) program supports fundamental research in the following BME themes: Neural engineering (brain science, computational neuroscience, brain-computer interface, neurotech, cognitive engineering) Cellular biomechanics (motion, deformation, and forces in biological systems; how mechanical forces alter cell growth, differentiation, movement, signal transduction, transport, cell adhesion, cell cytoskeleton dynamics, cell-cell and cell-ECM interactions; genetically engineered stem cell differentiation with long-term impact in tissue repair and regenerative medicine) The BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences.  The projects should focus on high impact transforming methods and technologies. The project should include methods, models and tools of understanding and controlling of living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and new novel methods of reducing health care costs through new technologies.

Recognizing that scientific and technological endeavors were becoming increasingly international, the foundation decided to facilitate the development of biomedical engineers with international experience and expertise. To serve this objective, the Whitaker International Fellows and Scholar program was initiated in 2005 by a fifteen-year endowment to the Institute of International Education. In the years since, the program has enabled nearly two hundred young biomedical engineers to spend one or two years overseas studying, doing research, and participating in collaborative projects. In accordance with the original plan, the last group of grantees received support through 2018. To further promote the overall program objective, in 2018 several grantees received funding to pursue initiatives of their own design. That set of activities, now designated as Concluding Initiative #1, will end at the end of 2020.

NCATS plans to support the research, development and testing of up to three biomedical reasoning tool prototypes for the Biomedical Data Translator for an estimated $1,000,000 total costs each. NCATS is utilizing a three-step application process (challenge-concept-proposal) for this expedited program. The duration of each award will be less than one year. All awardees will be expected to collaborate and cooperate with NCATS staff, one another and potentially other contributors to the overall program to maximize the exploration of the potential capabilities of Translator and to understand technical feasibility and challenges of having multiple groups build a single resource. All U.S. and foreign organizations and U.S. citizens are eligible to apply. This funding opportunity is open to U.S. and foreign organizations, including academic institutions and commercial entities; subcontracts are allowed. U.S. citizens may also apply as individuals and may be direct recipients of an award. Non-citizen individuals residing in the U.S. or foreign country not affiliated with either a U.S. or foreign organization are not eligible to be direct recipients of an award. Successful completion of the application process will require applicants to have specific skills related to translational research and software development. Applicants need to demonstrate technical skills, including familiarity with web communication protocols, a variety of programming languages and software stack, and general algorithmic techniques in the areas of artificial intelligence, machine learning, and knowledge engineering, as well as problem solving skills, especially creativity and persistence. Applicants familiar with languages and packages most useful for solving different tasks, the entire challenge process may take between 2 and 8 hours to complete.

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) and VentureWell have come together to support and expand DEBUT, a competition that recognizes undergraduate excellence in biomedical design and innovation. DEBUT challenges teams of students in undergraduate biomedical education to solve real-world problems in healthcare. Prizes of up to $20,000 will be awarded. Strong DEBUT submissions will demonstrate a mastery of analytical and design skills and capabilities; the ability to manage the product development process; the ability to work effectively in teams; and technical communication skills. Submissions will be judged on the following criteria: Significance of the problem being addressed Impact of the proposed solution on potential users and clinical care Innovative design Working prototype Additional prizes will be awarded to entries that also demonstrate: Market potential and economic feasibility Patentability

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) and VentureWell have come together to support and expand DEBUT, a competition that recognizes undergraduate excellence in biomedical design and innovation. DEBUT challenges teams of students in undergraduate biomedical education to solve real world problems in healthcare. Prizes of up to $20,000 will be awarded, with a total prize purse of $80,000. Strong DEBUT submissions will demonstrate a mastery of analytical and design skills and capabilities; the ability to manage the product development process; the ability to work effectively in teams; and technical communication skills. Submissions will be judged on the following criteria: Significance of the problem being addressed Impact of proposed solution on potential users and clinical care Innovative design Working prototype

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) and VentureWell hold the Design by Biomedical Undergraduate Teams (DEBUT) Challenge which recognizes undergraduate excellence in biomedical innovation. DEBUT will award a total of $100K to undergraduate student teams working on innovative solutions to unmet health and clinical problems. Revised Criteria for 2020 In light of the social distancing measures that kept most students from entering labs this year, we are modifying our criteria to acknowledge teams that had excellent ideas for healthcare innovations but could not build and/or test/debug a prototype. We also want to reward teams who were able to achieve a working prototype. For 2020, each team will receive an ideation score and a prototype score and the team's final score will be the higher of the two.

This FOA, issued by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), encourages applications from institutions that propose to establish new or to enhance existing team-based design courses in undergraduate Biomedical Engineering departments or programs. This FOA targets undergraduate students at the senior level but may also include junior undergraduates and first-year graduate students. Courses that address innovative and/or ground-breaking development, multidisciplinary/interdisciplinary training and clincial immersion are especially encouraged.

This initiative will support exploratory research leading to the development of innovative technologies for biomedical research. The program will recognize and reward high risk approaches with potential for significant impact.  Projects will entail a high degree of risk or novelty, which will be offset by a correspondingly high potential impact. However, the possible impact is likely to be far off. Application of the proposed technology to specific biomedical questions is considered beyond the scope of the program, and should not be included. Preliminary data demonstrating feasibility of the proposed approach indicates that the project is beyond the scope of this program and therefore unsuitable for this funding opportunity.   

The goal of theBiomedical Engineering(BME)program is to provide research opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life sciences in solving biomedical problems that serve humanity in the long-term. BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences. The projects should focus on high impact transformative methods and technologies. Projects should include methods, models and enabling tools of understanding and controlling living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and novel methods for reducing health care costs through new technologies. The long-term impact of the projects can be related to fundamental understanding of cell and tissue function, effective disease diagnosis and/or treatment, improved health care delivery, or product development.

The goal of theBiomedical Engineering(BME)program is to provide research opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life sciences in solving biomedical problems that serve humanity in the long-term. BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences. The projects should focus on high impact transformative methods and technologies. Projects should include methods, models and enabling tools of understanding and controlling living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and novel methods for reducing health care costs through new technologies. The long-term impact of the projects can be related to fundamental understanding of cell and tissue function, effective disease diagnosis and/or treatment, improved health care delivery, or product development.

The purpose of this BD2K Funding Opportunity Announcement (FOA) is to support the development, improvement and implementation of tools and approaches that increase the efficiency and effectiveness of digital curation processes used to characterize and describe the digital data used in or resulting from biomedical research.

The purpose of this BD2K Funding Opportunity Announcement (FOA) is to support the development, improvement and implementation of tools and approaches that increase the efficiency and effectiveness of digital curation processes used to characterize and describe the digital data used in or resulting from biomedical research.

The Centers of Excellence in Genomic Science (CEGS) program establishes academic Centers for advanced genome research.  Each CEGS grant supports a multi-investigator, interdisciplinary team to develop innovative genomic approaches to address a particular biomedical problem.  A CEGS project will address a critical issue in genomic science or genomic medicine, proposing a solution that would be a very substantial advance.  Thus, the research conducted at these Centers will entail substantial risk, balanced by outstanding scientific and management plans and very high potential payoff.  A CEGS will focus on the development of novel technological or computational methods for the production or analysis of comprehensive data sets, or on a particular genome-scale biomedical problem, or on other ways to develop and use genomic approaches for understanding biological systems and/or significantly furthering the application of genomic knowledge, data and methods towards clinical applications.  Exploiting its outstanding scientific plan and team, each CEGS will nurture genomic science at its institution by facilitating the interaction of investigators from different disciplines, and by providing training to new and experienced investigators, it will expand the pool of highly-qualified professional genomics scientists and engineers.

This Funding Opportunity Announcement (FOA) encourages bioengineering applications that will accelerate the development and adoption of promising tools and technologies that can address important biomedical research problems. The objectives are to establish these tools and technologies as robust, well-characterized solutions that fulfill an unmet need and are capable of enhancing our understanding of life science processes or the practice of medicine. Awards will focus on supporting multidisciplinary teams that apply an integrative, quantitative bioengineering approach to developing these technologies and engage biomedical researchers or clinicians throughout the project. The goal of the program is to support projects that can realize meaningful solutions within 5-10 years.

The goal of a Bioengineering Research Partnership (BRP) is to drive the development and speed the adoption of promising tools and technologies that can address important biomedical problems for which insufficient or no solutions exist.  The use of engineering principles is encouraged to establish these tools and technologies as robust, well-characterized solutions that fulfill an unmet need. A synergistic partnership between engineering and the life, physical, and computational sciences is also encouraged, where the unique skills of each discipline combine to enhance our understanding of life science processes or the practice of medicine. The purpose of this FOA is to encourage BRP applications that: 1) establish a robust engineering solution to a problem in biomedical research or the practice of medicine; 2) develop a strategic alliance of multidisciplinary partners based on a well-defined leadership plan; and 3) realize a specific endpoint within 5-10 years based on a detailed plan with a timeline and quantitative milestones.

The Biosensing program is part of the Engineering Biology and Health cluster, which also includes 1) the Biophotonics program; 2) the Cellular and Biochemical Engineering program; 3) the Disability and Rehabilitation Engineering program; and 4) the Engineering of Biomedical Systems program. The Biosensing program supports fundamental engineering research on devices and methods for measurement and quantification of biological analytes. Examples of biosensors include, but are not limited to, electrochemical/electrical biosensors, optical biosensors, plasmonic biosensors, and paper-based and nanopore-based biosensors. In addition to advancing biosensor technology development, proposals that address critical needs in biomedical research, public health, food safety, agriculture, forensic, environmental protection, and homeland security are highly encouraged. Proposals that incorporate emerging nanotechnology methods are especially encouraged.

The Greenwall Foundation is soliciting Letters of Intent for its Greenwall Faculty Scholars Program in Bioethics, a career development award designed to enable junior faculty members to carry out innovative bioethics research. Each year, around three Greenwall Faculty Scholars are selected to receive 50 percent salary support for three years to enable them to develop their research program. The program supports research focused on resolving pressing ethical issues in clinical care, biomedical research, and public policy. Scholars and alumni attend twice-yearly meetings, where they present their work in progress, receive feedback and mentoring from the Faculty Scholars Program Committee and other scholars, and have the opportunity to develop collaborations with other researchers. The ongoing involvement of alumni with the program provides them ongoing opportunities for professional development and feedback and engages them in mentoring of younger scholars.

The Greenwall Foundation is soliciting Letters of Intent for its Greenwall Faculty Scholars Program in Bioethics, a career development award designed to enable junior faculty members to carry out innovative bioethics research. Each year, around three Greenwall Faculty Scholars are selected to receive 50 percent salary support for three years to enable them to develop their research program. The program supports research focused on resolving pressing ethical issues in clinical care, biomedical research, and public policy. Scholars and alumni attend twice-yearly meetings, where they present their work in progress, receive feedback and mentoring from the Faculty Scholars Program Committee and other scholars, and have the opportunity to develop collaborations with other researchers. The ongoing involvement of alumni with the program provides them ongoing opportunities for professional development and feedback and engages them in mentoring of younger scholars.