Group items tagged

The purpose of this notice of funding opportunity is to identify and implement innovative strategies to better engage, detect, and manage glaucoma and other eye diseases among vulnerable populations, in community-based settings, for replication and scaling in the US. This NOFO will be accomplished with two components; Component A: Community-Based Interventions with Vulnerable Populations and Component B: Coordinating Center to provide logistics and support to the research study. Glaucoma is the leading cause of irreversible blindness among African Americans and the second leading cause of blindness worldwide. An estimated 2.2 to 2.7 million people in the United States have the disease. Due to its asymptomatic nature, half of people with glaucoma are unaware of their condition, increasing the severity of the disease. However, once detected, appropriate treatment and management can slow glaucoma progression and preserve the remaining vision, but cannot restore lost vision. Given the low general population prevalence of glaucoma, broad general population screening appears not to be cost-effective, and the marginal results from glaucoma screenings in high-risk population, it is reasonable to reach out to groups with higher prevalence (African Americans over age 40, Asians, older people [aged 65+ years] especially older Hispanics, those with a family history of glaucoma, and those with diabetes).

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research related to the role of the gut microbiome in regulating metabolism and reproduction, and its impact on the fertility status. The overarching goal is to gain fundamental insight into the possible role of the gut microbiome in regulating reproduction through HPG, HPA, and HPT axes in the brain. The results of the study could lead to development of diagnostic markers (signature microbiomes) for reproductive and metabolic failure. The project is pertinent to multiple portfolios in the Fertility and Infertility Branch, e.g., basic ovarian biology, fertility preservation, assisted reproductive technology, spermatogenesis and sperm function, and therapeutic interventions to infertility. The emphasis on the gut microbiome and its impact on reproduction through its effects on HPG, HPA, and HPT axes leading to obesity, metabolic syndrome, stress disorders, infection and anxiety is also of interest to the Maternal and Pediatric infectious disease Branch, Pediatric Growth and Nutrition Branch and IDDB.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research related to the role of the gut microbiome in regulating metabolism and reproduction, and its impact on the fertility status. The overarching goal is to gain fundamental insight into the possible role of the gut microbiome in regulating reproduction through HPG, HPA, and HPT axes in the brain. The results of the study could lead to development of diagnostic markers (signature microbiomes) for reproductive and metabolic failure. The project is pertinent to multiple portfolios in the Fertility and Infertility Branch, e.g., basic ovarian biology, fertility preservation, assisted reproductive technology, spermatogenesis and sperm function, and therapeutic interventions to infertility. The emphasis on the gut microbiome and its impact on reproduction through its effects on HPG, HPA, and HPT axes leading to obesity, metabolic syndrome, stress disorders, infection and anxiety is also of interest to the Maternal and Pediatric infectious disease Branch, Pediatric Growth and Nutrition Branch and IDDB.

This is a Task Agreement under a Youth Master Cooperative Agreement P15AC00031. The Recipient with recruit 2 interns. The purpose of this project is to provide youth hands-on experience in natural and cultural restoration and toenhance the scientific communities knowledge adding to the study/ monitoring of bats. This is in regards to the White Nose Syndrome (WNS),a deadly disease that affects North American bats. The work done by the interns will help the management and provide for public awareness. The primary goal is to continue with a landscape project involving 22 acres that was started in 2017.The objectives are to re-seed with native grasses and forbs. This project incorporates these public purposes: The information, products and/or services identified or developed by this project will be shared through a variety of strategies to increase public awareness, knowledge and support for historic preservation and stewardship of the nation's cultural and historical heritage. The principal purpose of the project is to support the Government's objective to provide opportunities for youth to learn about the environment by spending time working on projects in National Parks. The NPS receives the indirect benefit of completing conservation projects.

The American College of Cardiology's Accreditation Services help hospitals improve care for patients with acute coronary syndromes, heart failure, and atrial fibrillation. In 2016, ACC merged with the Society of Cardiovascular Patient Care (SCPC), a nonprofit organization dedicated to improving the care and outcomes of patients worldwide facing the same complications. To preserve the legacy of SCPC, an endowment was created to support future cardiovascular quality or performance improvement initiatives, particularly those that underscore the importance of accreditation. To advance that mission, ACCF is accepting proposals that support cardiovascular quality improvement of cardiovascular care and patient outcomes. Awards of up to $100,000 will support projects that contribute to the evidence base for accreditation; develop or evaluate cardiovascular quality initiatives that strengthen the accreditation process; provide opportunities for education that support quality or performance improvement projects; improve EMS systems of care in collaboration with community hospitals providing accreditation services; or provide public health education to improve community measures/outcomes related to early recognition of heart attack symptoms and appropriate action steps.

DARPA seeks novel approaches to reversibly pause and/or slow the functions and preserve viability of living cells without reliance on cold temperature. This new technology aims to directly address needs within the Department of Defense to maintain and deliver biological therapeutics and extend the window of time for effective use of field forward therapeutics. See the HR001118S0034 document attached.

Funded by NASA through a cooperative agreement, TRISH engages and enables new health technologies to predict, protect and preserve astronaut health during deep space exploration missions. We seek high risk, high reward, high quality and efficient solutions that can be adapted (or translated) for use in space. TRISH is seeking emerging scientific and biomedical advances, radically disruptive technologies, and new engineering capabilities.

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for projects that will rapidly and systematically implement new technologies into the HuBMAP Consortium with the goal of accelerating development of a framework for mapping of the human body at single cell resolution. The scope of this FOA encompasses a wide range of technologies, spanning the fields of tissue collection and preservation; high resolution, high content, high-throughput imaging; high sensitivity and high specificity transcriptomics, genomics and proteomics; analysis, and visualization and modelling of multidimension biomolecular data.

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for projects that will rapidly and systematically implement promising technologies into the HuBMAP Consortium with the goal of accelerating development of a framework for mapping of the human body at high resolution. The goal of the FOA is to broaden and deepen the Consortium's range of technologies and expertise spanning the fields of tissue collection and preservation; high resolution, high content, high-throughput imaging; high sensitivity and high specificity transcriptomics, genomics and proteomics; extracellular environment and matrix composition; analysis, and visualization and modelling of multidimension biomolecular data.

The CSBR program provides for enhancements that secure and improve existing collections, result in accessible digitized specimen-related data, and develop better methods for specimen curation and collection management. Requests should demonstrate a clear and urgent need to secure the collection, and the proposed activities should address that need. Biological collections supported include established living stock/culture collections, vouchered non-living natural history collections, and jointly-curated ancillary collections such as preserved tissues and DNA libraries.

T-lymphocytes preserve an immunological balance between attacking tumor cells and preventing a continued activated immune response. This balance is maintained by a network of protein interactions that can inhibit T-cell mediated immune responses targeted against self-antigens or stimulate them to defend against tumor cells. T-cell specificity against tumor cells is determined by the interaction between the T-cell receptor complex and antigenic peptides bound in the surface major histocompatibility complex molecules (MHC).

The Ohio Affiliate of  Prevent Blindness is accepting applications for its 2018 Young Investigator Student Fellowship Awards for Female Scholars in Vision Research. The Fellowship Program is designed to provide support for outstanding female scientists committed to pursuing biomedical, behavioral or clinical research careers relevant to the mission of Prevent Blindness - to prevent blindness and preserve sight.  Grants will be awarded for the summer 2018 session.  Awards will range from $3000-$5000 depending upon the availability of funds. The deadline for receipt of applications is Feb. 15, 2018. Applicants must be post-baccalaureate students enrolled in a master's or doctorate program during the summer of 2018, female, citizens or permanent residents of the United States, and conducting their research with a recognized academic institution in the State of Ohio. Applications from diverse fields in the health sciences including, but not limited to ophthalmology, optometry, nursing, genetics, public health, nutrition, gerontology, and bioengineering, are appropriate to the goals of this fellowship award. The Ohio Affiliate of Prevent Blindness encourages fellowship applications which investigate public health issues related to the burden of eye-related health and safety topics.

The purpose of this Funding Opportunity Announcement (FOA) is to establish state-of-the-art Tissue Mapping Centers (TMCs) that will generate high-resolution, high-content, multiscale maps of non-diseased human organs and systems. Centers will be expected to integrate and optimize all parts of the data generation pipeline, from tissue collection and preservation through to data integration, analysis and interpretation. Centers will also be expected to work closely with the other funded projects as part of the Human BioMolecular Atlas Program to catalyze development of a framework for mapping the human body at high resolution.

This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on the early-stage development of highly innovative technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies that improve the quality of the samples used for cancer research or clinical care. This includes the ability to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. FOA Emphasis. The FOA utilizes the R33 mechanism which is suitable for projects where proof-of-principle of the proposed technology or methodology has been demonstrated and supportive preliminary data are available. Proposed projects should offer new tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection, and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality.

This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on early-stage development of highly innovative technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. The emphasis of this FOA is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection, screening, clinical diagnosis, treatment, epidemiology, or address issues in cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality.

The purpose of this Funding Opportunity Announcement (FOA) is to establish state-of-the-art Tissue Mapping Centers (TMCs) that will generate high-resolution, high-content, multiscale maps of non-diseased human organs and systems. Centers will be expected to integrate and optimize all parts of the data generation pipeline, from tissue collection and preservation through to data integration, analysis and interpretation. Centers will also be expected to work closely with the other funded projects as part of the Human BioMolecular Atlas Program to catalyze development of a framework for mapping the human body at high resolution.

The Prevent Blindness Ohio Young Investigator Student Fellowship Awards for Female Scholars in Vision Research provides training support for future generations of outstanding female scientists committed to pursuing biomedical, behavioral or clinical research careers relevant to the mission of Prevent Blindness Ohio - to prevent blindness and preserve sight.  The fellowship awards provide partial support to younger investigators, promoting the development of scientific skills that will lead to more substantial funding from other sources.

Pandemics have far reaching consequences that range from deaths to shutting down the economy as we have witnessed during the recent COVID19 crisis. Hence there is a need to be better prepared for such pandemics. We need to solve problems ranging from predictive analytics innovative devices for saving lives to technology for devising voting machines. The social and economic impact for the above areas is huge and some of the work can be transformative and save lives. Areas of interest to us include, but are not limited to: - Mathematical models for spread and the impact of pandemics. - Scalable simulation techniques for pandemics (e.g. with multi agents). - Biomedical/Nano sensor devices for detecting symptoms and agents. - Algorithms for rapid exploration of the drug screening and discovery workflows (e.g. use reinforcement learning) - Advanced computational biology techniques for sequencing, detecting viral evolution (e.g. in COVID-19). - Algorithms and systems for contact tracing (with privacy preserving). - Algorithms and recommendation systems for curating media and news. - Collaboration techniques for more effective health, and efficiency during pandemics. Improved identity and security techniques. - Distributed Ledgers, their applications and their governance for and during pandemics. - Pandemic data science - understanding the patterns and the impact of a pandemic like COVID-10. Creation of curated data sets. We are interested in both the science and technology aspects of these problem sets, and, particularly, in the intersections between them.

In an effort to support cardiovascular quality and performance improvement, the ACC provides funding opportunities that support future cardiovascular quality initiatives (QI) or performance improvement (PI), particularly those that highlight the importance of accreditation. Funding to support these projects is made possible by the Society of Cardiovascular Patient Care (SCPC), which was a nonprofit organization dedicated to improving the care and outcomes of patients worldwide with suspected acute coronary syndrome, heart failure, and atrial fibrillation through innovative cross-disciplinary processes. Its merger with the American College of Cardiology Foundation (ACCF) in 2016 provided an opportunity to leverage the accreditation strength of the SCPC into the large portfolio of services the ACCF offers. To preserve the legacy of the SCPC, an endowment was created to support future cardiovascular QI or PI, particularly those efforts that highlight the importance of accreditation. Focus areas of desired projects or proposals include those that support cardiovascular quality improvement of cardiovascular care and patient outcomes that: contribute to the evidence base for accreditation develop or evaluate cardiovascular quality initiatives that strengthen the accreditation process provide opportunities for education that support quality or performance improvement projects improve EMS systems of care in collaboration with community hospitals providing accreditation services provide public health education to improve community measures/outcomes related to early recognition of heart attack symptoms and appropriate action steps