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MiamiOH OARS

Identification of Mechanisms Mediating the Effects of Sleep on Diabetes-Related Metabol... - 0 views

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    The purpose of this Funding Opportunity Announcement is to invite applications that investigate the mechanisms mediating the interactions between sleep and diabetes-related metabolism using deep metabolic phenotyping approaches in healthy human populations and those with metabolic and/or sleep disorders.
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    The purpose of this Funding Opportunity Announcement is to invite applications that investigate the mechanisms mediating the interactions between sleep and diabetes-related metabolism using deep metabolic phenotyping approaches in healthy human populations and those with metabolic and/or sleep disorders.
MiamiOH OARS

PA-15-169: Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21) - 0 views

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    This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses of existing data sets relevant to diabetes and selected endocrine and metabolic diseases including thyroid, parathyroid and Cushing's diseases and acromegaly; and genetic metabolic disease including cystic fibrosis, lysosomal storage diseases, and disorders of the urea cycle, amino acid metabolism and metal transport where the focus is on peripheral metabolism or organ function; obesity, liver diseases, alimentary GI tract diseases and nutrition; kidney, urologic, and hematologic diseases. The goal of this program is to facilitate research that explores innovative hypotheses through the use of existing data sets. 
MiamiOH OARS

Elucidating HIV and HIV-treatment Associated Metabolic/Endocrine Dysfunction (R01) - 0 views

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    The goal of this Funding Opportunity Announcement (FOA) is to support innovative research in humans to elucidate the role of HIV infection, including relevant host conditions or antiretroviral therapy, on metabolic and endocrine dysfunction, as well as to support innovative research delineating the pathophysiology, etiology, risk or protective factors, and potential strategies to prevent, treat, or reverse endocrine and metabolic dysfunction in HIV-infected individuals. Proposed projects must involve human subjects with HIV infection or materials or data from HIV-infected individuals. Proposed projects must also be related to the mission of the Division of Diabetes, Endocrinology, and Metabolic Diseases within NIDDK (DEM/NIDDK).
MiamiOH OARS

RFA-DK-17-036: Elucidating HIV and HIV-treatment Associated Metabolic/Endocrine Dysfunc... - 0 views

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    The goal of this Funding Opportunity Announcement (FOA) is to support innovative research to elucidate the role of HIV infection, including relevant host conditions or antiretroviral therapy, on metabolic and endocrine dysfunction, as well as to support innovative research delineating the pathophysiology, etiology, risk or protective factors, and potential strategies to prevent, treat, or reverse endocrine and metabolic dysfunction in HIV-infected individuals. This FOA supports both mechanistic research and clinical trials. Proposed projects must be related to the mission of the Division of Diabetes, Endocrinology, and Metabolic Diseases within NIDDK (DEM/NIDDK).
MiamiOH OARS

Role of Gut Microbiome in Regulating Reproduction and Its Impact on Fertility Status in... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research related to the role of the gut microbiome in regulating metabolism and reproduction, and its impact on the fertility status. The overarching goal is to gain fundamental insight into the possible role of the gut microbiome in regulating reproduction through HPG, HPA, and HPT axes in the brain. The results of the study could lead to development of diagnostic markers (signature microbiomes) for reproductive and metabolic failure. The project is pertinent to multiple portfolios in the Fertility and Infertility Branch, e.g., basic ovarian biology, fertility preservation, assisted reproductive technology, spermatogenesis and sperm function, and therapeutic interventions to infertility. The emphasis on the gut microbiome and its impact on reproduction through its effects on HPG, HPA, and HPT axes leading to obesity, metabolic syndrome, stress disorders, infection and anxiety is also of interest to the Maternal and Pediatric infectious disease Branch, Pediatric Growth and Nutrition Branch and IDDB.
MiamiOH OARS

Role of Gut Microbiome in Regulating Reproduction and Its Impact on Fertility Status in... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research related to the role of the gut microbiome in regulating metabolism and reproduction, and its impact on the fertility status. The overarching goal is to gain fundamental insight into the possible role of the gut microbiome in regulating reproduction through HPG, HPA, and HPT axes in the brain. The results of the study could lead to development of diagnostic markers (signature microbiomes) for reproductive and metabolic failure. The project is pertinent to multiple portfolios in the Fertility and Infertility Branch, e.g., basic ovarian biology, fertility preservation, assisted reproductive technology, spermatogenesis and sperm function, and therapeutic interventions to infertility. The emphasis on the gut microbiome and its impact on reproduction through its effects on HPG, HPA, and HPT axes leading to obesity, metabolic syndrome, stress disorders, infection and anxiety is also of interest to the Maternal and Pediatric infectious disease Branch, Pediatric Growth and Nutrition Branch and IDDB.
MiamiOH OARS

RFA-DK-17-035: Microphysiological Systems (MPS) for Modeling Diabetes (UG3/UH3 Clinical... - 0 views

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    NIDDK requests applications to join a new research consortium "Microphysiological Systems (MPS) for Modeling Diabetes (MPS-MOD)". NIDDK will support the development and validation of human tissue chips that closely mimic the normal physiology of key metabolic tissues, including the pancreatic islet, liver, skeletal muscle, and white adipose tissue (WAT). Experimental designs for the MPS-MOD platforms should incorporate strategies to measure pathophysiological changes associated with metabolic disease, including the impact of immune cells on metabolic dysfunction. Once developed, these multi-dimensional MPS-MOD platforms will serve as the foundation for NIDDK's advanced strategy to identify new and novel therapeutics for diabetes. The utility and validity of model systems developed under this initiative will be measured, in part, through the ability of known diabetes therapeutic agents and biomarkers to influence biology of the system, using best practices and rigorous study design. The need for high-quality, well-characterized isogenic/patient derived iPSC (induced pluripotent stem cell) lines and standardized differentiation procedures is a critical step in turning disease-specific lines into tools for discovery. In the future, iPSC-based human tissue chips could play a central role in drug development, testing, screening, drug repurposing and toxicity testing.
MiamiOH OARS

Elucidating HIV and HIV-treatment Associated Metabolic/Endocrine Dysfunction - 0 views

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    The goal of this Funding Opportunity Announcement (FOA) is to support innovative research in humans to elucidate the role of HIV infection, including relevant host conditions or antiretroviral therapy, on metabolic and endocrine dysfunction, as well as to support innovative research delineating the pathophysiology, etiology, risk or protective factors, and potential strategies to prevent, treat, or reverse endocrine and metabolic dysfunction in HIV-infected individuals. P
MiamiOH OARS

New Paradigms in Tissue Communication-from mediators to metabolic function (RC2 Clinica... - 0 views

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    NIDDK utilizes High Impact, Interdisciplinary Science (RC2) grants to support projects that will lay the foundation for new fields of investigation within the mission of NIDDK. The RC2 is envisioned to use an interdisciplinary approach to generate a research resource and/or foster discovery-based or hypothesis-generating science that can have a significant impact on the broader scientific community. This targeted FOA specifically seeks to generate scientific advancements that are focused on identifying new signals and regulatory networks that mediate metabolic cross talks within and between organs that play a role in the development of diabetes and obesity. The interdisciplinary approaches proposed should be designed to foster novel synergies that will accelerate conceptual and technical breakthroughs in science related to metabolic tissue communication.
MiamiOH OARS

Catalyst Award In Diabetes, Endocrinology and Metabolic Diseases (DP1 Clinical Trial No... - 0 views

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    The Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD) is designed to complement NIDDK's traditional, investigator-initiated grant programs by supporting individual scientists who propose pioneering andtransformational studies in DEMD topic areas. Applications should be focused on major scientific challenges, and have the potential to produce an unusually high impact on diseases and conditions that are central to the mission of NIDDK's Division of Diabetes, Endocrinology and Metabolic Diseases. To be considered responsive to this initiative, the proposed research should reflect new and novel scientific directions that are distinct from concepts and approaches being pursued in the investigators research program or elsewhere.
MiamiOH OARS

Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (DP1- Clinical Trial N... - 0 views

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    The Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD) is designed to complement NIDDK's traditional, investigator-initiated grant programs by supporting individual scientists who propose pioneering and possibly transforming studies in DEMD topic areas. Applications should be focused on major scientific challenges, and have the potential to produce an unusually high impact on diseases and conditions that are central to the mission of NIDDK's Division of Diabetes, Endocrinology and Metabolic Diseases. To be considered responsive to this initiative, the proposed research must reflect new and novel scientific directions that are distinct from concepts and approaches being pursued in the investigators research program or elsewhere.
MiamiOH OARS

RFA-DK-17-011: Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (DP1- C... - 0 views

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    The Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (Catalyst-DEMD) is designed to complement NIDDK's traditional, investigator-initiated grant programs by supporting individual scientists who propose pioneering and possibly transforming studies in DEMD topic areas. Applications should be focused on major scientific challenges, and have the potential to produce an unusually high impact on diseases and conditions that are central to the mission of NIDDK's Division of Diabetes, Endocrinology and Metabolic Diseases. To be considered responsive to this initiative, the proposed research must reflect new and novel scientific directions that are distinct from concepts and approaches being pursued in the investigator's research program or elsewhere.
MiamiOH OARS

CONFERENCE: Ohio Valley Affiliates for Life Sciences (OVALS) - 0 views

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    Metabolic Disease: Solving Challenges through New Technologies and Novel Approaches    March 28, 2014    ·    Kingsgate Mariott Conference Center    ·   Cincinnati, OH This year's conference will look at Obesity, Diabetes, and Metabolic Disease: NIH funding trends, priorities and opportunities Industry trends and priorities and implications for University research Forming successful multi-institutional partnerships to solve major health problems Start-up Company Spotlight: connecting start-up opportunities to resources Showcase of promising university life sciences technologies poised to change lives Technology Poster Competition
MiamiOH OARS

ASPEN Roads Research Foundation Invites Applications for Metabolic, Clinical Nutrition ... - 0 views

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    ASPEN is accepting applications to its annual Rhoads Research Foundation Grants program. Through the program, grants of $25,000 (renewable for one year) and $10,000 (non-renewable) will be awarded to exceptional early-career investigators in support of clinical metabolic and nutrition support research in alignment with the priorities outlined in the ASPEN Research Agenda. Research supported by the foundation includes both basic science-oriented investigations aimed at improving the understanding of the science of nutrient regulation in different disease states, as well as clinical and translational research to determine how the practice of nutrition support can continue to be refined and individualized to optimize clinical outcomes.
MiamiOH OARS

ASPEN | ASPEN Rhoads Research Foundation Annual Grants - 0 views

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    The ASPEN Rhoads Research Foundation, the philanthropic arm of the American Society for Parenteral and Enteral Nutrition, is dedicated to improving patient care by advancing the science and practice of clinical nutrition and metabolism. Founded in 1976, ASPEN is an interdisciplinary organization whose members are involved in the provision of clinical nutrition therapies, including parenteral and enteral nutrition. With more than sixty-five hundred members from around the world, ASPEN is a community of dietitians, nurses, pharmacists, physicians, scientists, students, and other health professionals from every facet of nutrition support clinical practice, research, and education. To advance its mission, the foundation is accepting applications for its ASPEN Rhoads Research Foundation Grants program. Through the annual program, grants of up to $25,000 will be awarded for research projects by early-career investigators focused on clinical nutrition and metabolic support in alignment with the priorities outlined in the ASPEN Research Agenda.
MiamiOH OARS

JDRF Grant - 0 views

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    One of JDRF's therapeutic goals is to restore beta cell function in type 1 diabetes (T1D) by replacement/transplantation of beta cells/islets. Pancreatic islet transplantation has been efficacious in selected patients in improving metabolic control and quality of life, and in preventing severe hypoglycemia in patients with medically unstable T1D. Despite improvements in cadaveric pancreas procurement, islet isolation, and islet purification, major scientific and technical challenges remain that must be addressed before beta cell replacement could be widely incorporated into the clinical management of established T1D; examples include serious side effects from chronic immunosuppression and the insufficient human islet supply from cadaveric pancreata. JDRF's role is to enable the scientific community to address these challenges with the ultimate goal of developing safe and effective beta cell replacement approaches available to large numbers of individuals with T1D.
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    One of JDRF's therapeutic goals is to restore beta cell function in type 1 diabetes (T1D) by replacement/transplantation of beta cells/islets. Pancreatic islet transplantation has been efficacious in selected patients in improving metabolic control and quality of life, and in preventing severe hypoglycemia in patients with medically unstable T1D. Despite improvements in cadaveric pancreas procurement, islet isolation, and islet purification, major scientific and technical challenges remain that must be addressed before beta cell replacement could be widely incorporated into the clinical management of established T1D; examples include serious side effects from chronic immunosuppression and the insufficient human islet supply from cadaveric pancreata. JDRF's role is to enable the scientific community to address these challenges with the ultimate goal of developing safe and effective beta cell replacement approaches available to large numbers of individuals with T1D.
MiamiOH OARS

Elucidating the Role of the Autonomic Nervous System in Peripheral Metabolism and Metab... - 0 views

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    This is a Task Agreement under a Youth Master Cooperative Agreement P15AC00031. The Recipient with recruit 2 interns. The purpose of this project is to provide youth hands-on experience in natural and cultural restoration and toenhance the scientific communities knowledge adding to the study/ monitoring of bats. This is in regards to the White Nose Syndrome (WNS),a deadly disease that affects North American bats. The work done by the interns will help the management and provide for public awareness. The primary goal is to continue with a landscape project involving 22 acres that was started in 2017.The objectives are to re-seed with native grasses and forbs. This project incorporates these public purposes: The information, products and/or services identified or developed by this project will be shared through a variety of strategies to increase public awareness, knowledge and support for historic preservation and stewardship of the nation's cultural and historical heritage. The principal purpose of the project is to support the Government's objective to provide opportunities for youth to learn about the environment by spending time working on projects in National Parks. The NPS receives the indirect benefit of completing conservation projects.
MiamiOH OARS

Grants.gov - Find Grant Opportunities - Opportunity Synopsis - 0 views

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    This Developmental Research Funding Opportunity intends to support gene function studies in collaboration with the Undiagnosed Diseases Network (UDN) building upon the NIH Intramural Research Programs Undiagnosed Diseases Program (NIH-UDP). Responsive applications will propose to investigate the underlying genetics, biochemistry and/or pathophysiology of newly diagnosed diseases in association with the respective gene variant(s) identified through the UDN. In recent years, gene function studies combined with genetic and genomic analyses and metabolic studies have greatly improved diagnoses of these very rare diseases and advanced scientific knowledge of the underlying pathogenesis. This initiative is funded through the NIH Common Fund, which supports cross-cutting programs that are expected to have exceptionally high impact.
MiamiOH OARS

Biomedical Analysis of Human Biospecimens for the Division of Epidemiology, Statistics,... - 0 views

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    The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), the Division of Epidemiology, Statistics, and Prevention Research intends to solicit proposals to award an Indefinite Delivery Indefinite Quantity (IDIQ) contract to an organization to conduct various studies focusing on a spectrum of health effects in men, women, and children that rely on quantification of analytes in biological specimens such as blood, urine, adipose tissue, follicular fluids, and seminal fluids.  The Division needs a variety of banked specimens analyzed for concentrations of various hormone levels, dietary biomarkers, and indicators of metabolic function among other analytes.
MiamiOH OARS

MDA Research Grants Programs | MDA - 0 views

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    MDA supports research aimed at developing treatments for the muscular dystrophies and related diseases of the neuromuscular system. These are the muscular dystrophies (among which are Duchenne and Becker); motor neuron diseases (including ALS and SMA); the peripheral nerve disorders (CMT and Friedreich's ataxia); inflammatory myopathies; disorders of the neuromuscular junction; metabolic diseases of muscle as well as other myopathies.
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