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MiamiOH OARS

National Dental Practice-Based Research Network: Clinical Trial or Observational Study ... - 0 views

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    The National Institute of Dental and Craniofacial Research (NIDCR) intends to continue support for research conducted within a national Dental Practice-Based Research Network (DPBRN). The NIDCR will fund one national DPBRN Administrative and Resource Center (RFA-DE-19-001) and one national DPBRN Coordinating Center (RFA-DE-19-002) as companion awards to support the infrastructure for and implementation of multiple observational studies and clinical trials. This Funding Opportunity Announcement (FOA) is soliciting applications for investigator-initiated clinical observational studies and clinical trials to be conducted in the DPBRN through a milestone-driven UG3/UH3 cooperative agreement mechanism. Each UG3/UH3 award will support an individual project which will utilize the DPBRN infrastructure and resources for study planning and implementation. This FOA supports a UG3 clinical study planning phase and potential transition to a UH3 implementation phase, with a combined total funding period of up to six years. Progression to the UH3 phase is based on an administrative review and is dependent on success in meeting UG3 milestones, consideration of the DPBRN as an appropriate venue for conduct of the research, NIDCR program priorities, and availability of funds. The main goals of the national DPBRN are to streamline the implementation of national oral health research studies in dental practices on topics of importance to practitioners and their patients, to provide evidence useful in daily patient care, and to facilitate the translation of research findings into clinical practice.
MiamiOH OARS

Request for Applications - The Chan Zuckerberg Initiative - 0 views

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    The Human Cell Atlas (HCA) is a global effort to create a reference map of all cell types in the human body. It is an ambitious goal to generate a fundamental reference for biomedical research. The HCA was born out of advances in single cell biology that made it conceivable to collect extensive measurements that inform our understanding of cellular heterogeneity in health and disease. Due to the growth of the community, pace of technology, and interest from the international community, the project has gone from conceivable to feasible. The Chan Zuckerberg Initiative and the Helmsley Charitable Trust are pleased to announce continued support for the Human Cell Atlas by collaborating on two new funding mechanisms that the community can access through a single application portal. The Chan Zuckerberg Initiative seeks to continue the work of the HCA community with a focus on interdisciplinary work and collaboration through the formation of 3 year Seed Networks. The Helmsley Charitable Trust welcomes applications that will construct a detailed atlas of the human gut. CZI Seed Networks aim to solidify growth of the community and result in a first draft of several organs - there is no requirement for a gut component in CZI applications. Additionally, newly formed Networks are designed to catalyze partnership among the scientific community and the funding community so that we can work together toward a first draft of the HCA.
MiamiOH OARS

Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Justice Communi... - 0 views

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    The National Institute on Drug Abuse (NIDA) intends to publish a series of Funding Opportunity Announcements (FOA) for Cooperative Agreements to solicit applications for a network of researchers collaborating across justice and community-based service settings to transform community-level responses to opioid misuse and opioid use disorder in justice-involved populations. Opioid misuse and opioid use disorder consequences exist at the intersection of health and justice systems. Improving the capacity of the justice system to respond to opioid crisis with evidence-based approaches that include the use of medications for OUD requires strong partnerships between justice systems and healthcare as well as other community based organizations. Supporting the development of these relationships and novel models of justice-healthcare and other community collaborations is a critical target in addressing the current opioid crisis. NIDA is interested in launching a network of investigators who can rapidly conduct research to address the opioid crisis in justice settings. A variety of research methods will be used, including clinical trials, implementation science research, policy evaluations and/or modeling approaches. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and appropriate projects. This FOA is expected to use a multicomponent cooperative agreement mechanism. The FOA is expected to be published in October 2018 with an expected application due date in December 2018.
MiamiOH OARS

Limited Competition for the Continuation of Cure Glomerulonephropathy (CureGN) Particip... - 0 views

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    The purpose of this Limited Competition is to extend the Cure Glomerulonephropathy (CureGN) Network by continuing to support the Participating Clinical Centers (PCCs). The CureGN Network is a multicenter observational cohort study of glomerular disease patients with the goal of improving care for all glomerular disease patients. The operational components of the study include four multi-site PCCs and a Data Coordinating Center (DCC). The CureGN Network, established in 2013, has recruited nearly 2,200 of 2,400 planned study participants and followed them with annual in-person clinic visits and interim telephone contacts. The CureGN PCCs will continue to follow-up previously enrolled participants. The PCCs will optimize retention strategies, developing novel methods for "remote" or "virtual" study participation; ensure complete and accurate data collection with a focus on clinical assessment of disease activity and outcomes; and participate in the development and validation of study-wide semi-quantitative assessment of histopathologic lesions. It is expected that a focus on disease features unique to glomerulonephropathy, and outcomes relevant to the full range of patient experience, combined with carefully curated clinical and biochemical data will uncover new predictors of the disease course, pathophysiologic processes, disease subtypes and novel treatment targets.The DCC provides key leadership functions for this study in the areas of study organization, study design and implementation, overall management, data management and analysis, and biosample management. The DCC requirements are described under a separate FOA.
MiamiOH OARS

RFA-RM-18-025: Innovative Technologies to Non-Invasively Monitor Genome Edited Cells In... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to support the development of innovative technologies to non-invasively label and monitor genome edited cells in vivo. The ultimate goal for these technologies is to inform on safety and efficacy of in vivo genome editing over time.
MiamiOH OARS

RFA-RM-18-022: Development of Cell and Tissue Platforms to Detect Adverse Biological Co... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications that propose to develop and validate cell- and tissue-based platforms for assessing potential adverse biological consequences of somatic cell genome editing.
MiamiOH OARS

RFA-HL-19-021: Molecular Atlas of Lung Development Program (LungMAP) Phase 2 - Human Ti... - 0 views

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    The overall objective of the LungMAP is to better understand human lung development by building an open-access reference resource of a comprehensive, dynamic, 3-D molecular atlas of the late-stage developing human lung with data and reagents available to the research community. Phase 1 of the LungMAP has generated foundational data from developing mouse and human lungs, created a web portal for public data sharing, and established a repository of human lung tissues. Phase 2 of the LungMAP will continue to generate and integrate high-resolution, multiscale molecular profiles associated with spatial information to provide molecular characterizations of functionally and anatomically defined cell types in the developing human lung. Phase 2 of LungMAP will focus on human lung only and will extend the scope to cover normal lung development into early adulthood (up to 25 years old), as well as abnormal lung development in selected neonatal and pediatric rare lung diseases.

MiamiOH OARS

BLM MT/DAK Noxious Weed Control - 0 views

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    The purpose of this project is to assist BLM with Integrated Weed Management in ooperative Weed Management Areas and across ownerships.
MiamiOH OARS

Elucidating the Functional Roles of Non-Coding RNAs in Viral Infectious Diseases (R21 C... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to support exploratory and developmental research projects to uncover functional roles of non-coding RNAs (ncRNAs) in viral infectious diseases. Importantly, the projects should focus on functional characterization and mechanistic studies of previously identified ncRNAs. Applications limited to the discovery or identification of ncRNAs will not be supported under this RFA.
MiamiOH OARS

Enhancing Developmental Biology Research at Academic Research Enhancement Award Eligibl... - 0 views

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    This Funding Opportunity Announcement (FOA) encourages grant applications to strengthen the developmental biology research environment at educational institutions that provide baccalaureate or advanced degrees, but that have not been major recipients of NIH support. In addition, this FOA attempts to foster the development of novel or underutilized experimental model systems, and to motivate students through exposure to and participation in research projects designed to study fundamental processes underlying normal development.
MiamiOH OARS

Funding | Human Frontier Science Program - 0 views

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    The HFSP supports novel, innovative and interdisciplinary basic research focused on the complex mechanisms of living organisms; topics range from molecular and cellular approaches to systems and cognitive neuroscience and the interactions between organisms. A clear emphasis is placed on novel collaborations that bring biologists together with scientists from fields such as physics, mathematics, chemistry, computer science and engineering to focus on problems at the frontier of the life sciences.
MiamiOH OARS

Request for Applications | The Chan Zuckerberg Initiative - 0 views

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    The CZI Neurodegeneration Challenge Network has three goals: (1) to make fundamental advances toward understanding neurodegeneration; (2) to bring new ideas and talent to the field of neurodegeneration; and (3) to encourage a new type of interdisciplinary collaborative research involving scientists, clinicians and engineers.

    We invite applications to join the Neurodegeneration Challenge Network through two RFA mechanisms:

    CZI Ben Barres Early Career Acceleration Awards: five-year investigator grants for early career academic investigators, with an emphasis on those who are new to the field of neurodegeneration. We seek to empower investigators to pursue bold ideas and to take risks within a supportive and collaborative environment. Awardees will benefit from mentorship support, as well as professional development, training and network opportunities, and practical career guidance to help them navigate this early stage of their careers. It is with great pleasure that we name this Award in memory of Dr. Ben Barres. Through his research career and his life and humanity, Ben embodied both the spirit and the scientific aims of this Award and the Challenge Network approach.

    CZI Collaborative Science Awards: three-year grants for small group interdisciplinary collaborations. At least one member of the collaboration should be a physician with active clinical engagement in an area relevant to the proposal. These grants are aimed to support innovative, bold, high risk/high impact projects at the interface of basic and disease biology. The scope of these collaborations should focus on foundational science (as opposed to translation and clinical application), aligned with clinical context.
MiamiOH OARS

RFA-MH-19-130: NIMH Biobehavioral Research Awards for Innovative New Scientists (NIMH B... - 0 views

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    The NIMH Biobehavioral Research Awards for Innovative New Scientists (BRAINS) award is intended to support the research and research career advancement of outstanding, exceptionally productive scientists who are in the early, formative stages of their careers and who plan to make a long term career commitment to research in specific mission areas of the NIMH. This award seeks to assist these individuals in launching an innovative clinical, translational, basic or services research program that holds the potential to profoundly transform the understanding, diagnosis, treatment, or prevention of mental disorders. The NIMH BRAINS program will focus on the research priorities and gap areas identified in the NIMH Strategic Plan and the Research Domain Criteria (RDoC) project.
MiamiOH OARS

Dannon Accepting Applications for Gut Microbiome Fellowship | RFPs | PND - 0 views

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    Established in 2012, the program has expanded to include the gut microbiome in recognition of its remarkable potential on the human body - including immune health, brain health, and proper digestion and absorption. To date, the program has supported research on the use of foods as a delivery vector for beneficial bacteria, technology for studying the adaptation of fermentative microbes to milk, the effects of protein fermentation on the human microbiota and digestive health, and the relationship between probiotics, the gut microbiome and brain function.

MiamiOH OARS

RFA-HL-19-012: Deciphering the Molecular Landscape of Lung Aging in Humans (U01 - Clini... - 0 views

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    Age is the number one risk factor for diagnosis of many age-related lung diseases, including COPD and pulmonary fibrosis. Despite this, little is known regarding the interactions that likely occur between the molecular and cellular mechanisms of disease and the changes in molecules and cells that can be attributed to normal aging. In fact, very little is known about the normal aging process in the lung at the cellular and molecular level. In 2015, the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute on Aging (NIA) co-sponsored a workshop that identified a major knowledge gap in the understanding of normal lung aging in humans, as well as the need to develop a map of molecular changes that occur during normal aging in the lung that can serve as a reference for studies of age-related lung diseases.

MiamiOH OARS

Female Fellowship Applications 2018 | Prevent Blindness Ohio - 0 views

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    The Ohio Affiliate of  Prevent Blindness is accepting applications for its 2018 Young Investigator Student Fellowship Awards for Female Scholars in Vision Research. The Fellowship Program is designed to provide support for outstanding female scientists committed to pursuing biomedical, behavioral or clinical research careers relevant to the mission of Prevent Blindness - to prevent blindness and preserve sight. 

    Grants will be awarded for the summer 2018 session.  Awards will range from $3000-$5000 depending upon the availability of funds. The deadline for receipt of applications is Feb. 15, 2018. Applicants must be post-baccalaureate students enrolled in a master's or doctorate program during the summer of 2018, female, citizens or permanent residents of the United States, and conducting their research with a recognized academic institution in the State of Ohio.

    Applications from diverse fields in the health sciences including, but not limited to ophthalmology, optometry, nursing, genetics, public health, nutrition, gerontology, and bioengineering, are appropriate to the goals of this fellowship award. The Ohio Affiliate of Prevent Blindness encourages fellowship applications which investigate public health issues related to the burden of eye-related health and safety topics.
MiamiOH OARS

FY18 Funding Opportunity Announcement (FOA) for the Office of Naval Research (ONR) Navy... - 0 views

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    his announcement explicitly encourages projects that improve the capacity of education systems and communities to create impactful STEM educational experiences for students and workers. Submissions are encouraged to consider including active learning approaches and incorporating 21st century skill development. Projects must aim to increase student and worker engagement in STEM and enhance people with needed Naval STEM capabilities. ONR encourages applications to utilize current STEM educational research for informing project design and advancing our understanding of how and why people choose STEM careers and opportunities of naval relevance. While this announcement is relevant for any stage of the STEM educational system, funding efforts will be targeted primarily toward projects addressing the below communities or any combination of these communities: * Secondary education communities; * Post-Secondary communities; * Informal science communities; * Current naval STEM workforce communities. Project scope may range in size and complexity. Projects that are already established with prior funding sources or have established stakeholders are especially encouraged to consider the following scope areas: * Develop and implement exploratory pilot projects that seek to create new educational experiences within educational and training communities. * Develop larger cohesive STEM education and training activities that strengthen the capacity of regional communities and stakeholders to improve STEM education and training.
MiamiOH OARS

Population Health Interventions: Integrating Individual and Group Level Evidence (R21)-... - 0 views

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    To improve health and reduce the burden of disease, scientific research needs to be implemented at the population level in addition to the biological and clinical levels. The purpose of this funding opportunity announcement (FOA) is to support multilevel, transdisciplinary population health interventions that target underlying social, economic, and environmental conditions in an effort to improve health outcomes.
MiamiOH OARS

RFA-AG-18-023: Pathogenesis of Age-Related HIV Neurodegeneration (R01 Clinical Trial No... - 0 views

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    There is a global trend in the rise of HIV among older adults. In 2013, an estimated 42% of Americans living with HIV were at least 50 years old, 25% were at least 55 years old, and 6% were at least 65 years old. Since the advent of combination antiretroviral therapy to treat HIV, people infected with the virus have been living longer and experiencing fewer of the medical conditions directly attributable to HIV infection and AIDS. However, with longer life expectancy, individuals living with long-term HIV infection exhibit many clinical characteristics commonly observed in aging: multiple chronic diseases or conditions, the use of multiple medications, and changes in physical and cognitive abilities.
MiamiOH OARS

Research Coordination Networks in Undergraduate Biology Education - 0 views

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    The goal of the RCN program is to advance a field or create new directions in research or education by supporting groups of investigators to communicate and coordinate their research, training, and educational activities across disciplinary, organizational, geographic, and international boundaries. The RCN-UBE program originated as a unique RCN track to “catalyze positive changes in biology undergraduate education” (NSF 08-035) and is now supported by the collaborative efforts of the Directorate for Biological Sciences (BIO) and the Directorate for Education and Human Resources (EHR). It has been responsive to the national movement to revolutionize undergraduate learning and teaching in the biological sciences as described in the “Vision and Change in Undergraduate Biology Education” report. The RCN-UBE program seeks to improve undergraduate biology in different areas by leveraging the power of a collaborative network. The theme or focus of an RCN-UBE proposal can be on any topic likely to advance the goal of enhancing undergraduate biology education. Collectively, the program has contributed to developing and disseminating educational research resources and modules, to forging of new collaborations, and to sharing of best practices and ideas for scalability and sustainability of activities. These efforts have involved a large cadre of faculty, students, and other stakeholders. Proposed networking activities directed to the RCN-UBE program should focus on a theme to give coherence to the collaboration.
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