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MiamiOH OARS

NineSights Community - Need: 2aPowder Sterilization Technologies 2c - 0 views

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    Treatment of these powders by way of irradiation can be effective, however, this technique is not permitted without proper labeling in certain global regions. Given the large surface area of the powders in question, other methods of microbial eradication have typically been ineffective.

MiamiOH OARS

BLM-NM Genetic Association Project for Kuenzler's Hedgehog Cactus (Echinocereus fendler... - 0 views

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    Background: Kuenzler's Hedgehog Cactus (Echinocereus fendleri var. kuenzleri) is a federally listed species under the Endangered Species Act (ESA). It shares many similarities with a common species, Fendler's Hedgehog Cactus (Echinocereus fendleri var. fendleri) and with many intermediates. This has caused confusion for land managers. The BLM management of Kuenzler's Hedgehog Cactus impacts the multiple uses (i.e. public land users) across the landscape as it restricts land management decisions in order to conserve the imperiled species. Currently, there is no information on the genetic differences of the Kuenzler's Hedgehog Cactus, the Fendler's Hedgehog Cactus, and intermediaries. Without this information it is difficult to determine importance of populations in order to prioritize recovery actions to enable the species to be de-listed. The use of the most current genetic methods for defining species, plastome sequencing, microsatellite development and genotyping, and ddRAD sequencing is needed to accurately determine whether the two species and associated intermediates are in fact the same. If studies show there are two different varieties it will be important to understand how the different Kuenzler's Hedgehog Cactus populations are related to each other across the landscape. This information can help the BLM prioritize populations according to rarity of the element occurrences. The objective of this project is to determine the genetic differences and similarities between Kuenzler's Hedgehog Cactus (all known element occurrences), Fendler's Hedgehog Cactus, and associated intermediates as well as the differences in population structure of the element occurrences of Kuenzler Hedgehog Cactus across the landscape in order to assist with land management decisions and potential de-listing of the species.
MiamiOH OARS

Alzheimer's Drug Delivery Foundation Issues RFP for Biomarker Studies | RFPs | PND - 0 views

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    Clinical trials for Alzheimer's disease and related dementias have been hindered, in part, by the limited number of biomarkers available to (1) accurately diagnose these diseases; (2) enrich and stratify patient cohorts; (3) demonstrate target engagement for novel therapeutics; and (4) reliably monitor disease progression and response to treatment. While currently available biomarkers have helped to accelerate clinical trials, most are either expensive, invasive, or both, and only provide information on a small number of disease targets. Therefore, additional biomarkers are needed to provide a more complete picture of the disease.

MiamiOH OARS

Research Coordination Networks (RCN) (nsf17594) | NSF - National Science Foundation - 0 views

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    The RCN program provides opportunities to foster new collaborations, including international partnerships, and address interdisciplinary topics. Innovative ideas for implementing novel networking strategies, collaborative technologies, training, broadening participation, and development of community standards for data and meta-data are especially encouraged. RCN awards are not meant to support existing networks; nor are they meant to support the activities of established collaborations. RCN awards also do not support primary research.
MiamiOH OARS

Encouraging Development of Novel Amelogenesis Models (UG3/UH3 Clinical Trial Not Allowed) - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications to develop physiologically relevant models of amelogenesis that are robust and validated so that they can advance studies of healthy and diseased human conditions involving teeth. The objectives of this FOA are two-fold: 1) generate new and improved models that closely mimic physiological enamel development and maturation to empower studies of amelogenesis, and 2) validate those models to ensure they are robust and accurately reflect human physiology and pathology. These tandem objectives will be accomplished with an Exploratory/Developmental Phased Award Cooperative Agreement (UG3/UH3) mechanism, where the UG3 developmental phase is initiated and carried out through a milestone-driven process which will then be assessed to determine if advancement to the UH3 phase providing subsequent support to further advance the UG3 outcomes will be granted . It is expected this FOA will enhance the capability of resources to serve biomedical research and accelerate understanding of multiscale processes of enamel formation to inform strategies to mitigate diseases affecting enamel and associated structures.
MiamiOH OARS

Drug Transport Across the Blood-Testis and Blood-Epididymal Barriers (R61/R33 - Clinica... - 0 views

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    The purpose of this funding opportunity announcement (FOA) is to support research to elucidate the chemical features of non-native molecules that cross the blood-testis and/or blood-epidydimal barriers.
MiamiOH OARS

Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and M... - 0 views

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    The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams.

MiamiOH OARS

Leadership Group for a Clinical Research Network on Antibacterial Resistance (UM1 Clini... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to continue a Leadership Group (LG) for a Clinical Research Network on Antibacterial Resistance (AR), which was initiated to develop, implement, and manage a clinical research program to address key clinical research questions in AR. The LG is a cohesive program dependent on the highly integrated and complimentary activities of the four centers that comprise the network: Scientific Leadership Center (SLC), Clinical Operations Center (COC), Laboratory Center (LC) and Statistics and Data Management Center (SDMC).
MiamiOH OARS

ARVO Foundation Invites Applications for Age-Related Macular Degeneration Fellowships |... - 0 views

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    To that end, the foundation is inviting applications for two Genentech Age-Related Macular Degeneration Research Fellowships. A grant of $40,000 will be awarded to a researcher conducting basic research on AMD, while a second grant of $40,000 will be awarded to a researcher for translational AMD research focused on therapeutics.

MiamiOH OARS

Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and M... - 0 views

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    The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams.
MiamiOH OARS

Administrative Supplements to Promote Collaborative Activities in Basic Cancer Research... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to incentivize collaborative, multidisciplinary research across a broad area of challenging topics in basic cancer biology. These supplement applications must propose a collaboration between at least two researchers, one being the PI of the parent NCI grant. Awarded supplements will leverage and extend currently funded cancer research in the parent grant.
MiamiOH OARS

Oncology Co-Clinical Imaging Research Resources to Encourage Consensus on Quantitative ... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement applications to develop research resources that will encourage a consensus on how Quantitative Imaging (QI) methods are optimized to improve the quality of imaging results for co-clinical trials. The scientific goals of this FOA are to: (a) perform the appropriate optimization of the pre-clinical quantitative imaging methods, (b) implement the optimized methods in the co-clinical trial, and finally (c) populate a web-accessible research resource with all the data, methods, workflow documentation, and results collected from the co-clinical investigations. Co-clinical trials are defined in this FOA as investigations in patients and in parallel (or sequentially) in mouse or human-in-mouse models of cancer that mirror the genetics and biology of the patients malignancies or pre-cancerous lesions. The co-clinical trial should include either (a) a therapeutic goal, such as the prediction, staging, and/or measurement of tumor response to therapies, or (b) a screening and early detection or a cancer risk stratification goal for lethal cancer versus non-lethal disease. Applicants are encouraged to organize multi-disciplinary teams with experience in mouse models research, human investigations, imaging platforms, QI methods, decision support software and informatics to populate the research resource.
MiamiOH OARS

Investigator Initiated Research in Computational Genomics and Data Science (R21 Clinica... - 0 views

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    The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and biological systems. All proposals should address how the methods would scale to address larger and larger data sets.
MiamiOH OARS

Elucidating the Functional Roles of Non-Coding RNAs in Viral Infectious Diseases (R21 C... - 0 views

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    The purpose of this Funding Opportunity Announcement (FOA) is to support exploratory and developmental research projects to uncover functional roles of non-coding RNAs (ncRNAs) in viral infectious diseases. Importantly, the projects should focus on functional characterization and mechanistic studies of previously identified ncRNAs. Applications limited to the discovery or identification of ncRNAs will not be supported under this RFA.
MiamiOH OARS

Global Infectious Disease Research Training Program (D43 Clinical Trial Optional) - 0 views

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    This Funding Opportunity Announcement (FOA) encourages applications for the Global Infectious Disease (GID) Research Training Program from U.S. and low- and middle-income country (LMIC) institutions. The application should propose a collaborative training program that will strengthen the capacity of an LMIC institution to conduct infectious disease research. FIC will support research-training programs that focus on major endemic or life-threatening emerging infectious diseases, neglected tropical diseases, infections that frequently occur as co-infections in HIV infected individuals or infections associated with non-communicable disease conditions of public health importance in LMICs
MiamiOH OARS

RFA-AG-19-011: Integrative Omics to Enhance Therapeutics Development for Healthy Aging ... - 0 views

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    This Funding Opportunity Announcement (FOA) is a phased innovation initiative to facilitate multi-omics/integrative approaches to identify omics profiles associated with protection against multiple aging conditions, with exceptional health span, and to refine strategies for utilizing these profiles for therapeutics development. Specifically, a phased innovation cooperative agreement mechanism (UH2/UH3) involving an interdisciplinary research team will be used to support a single project that will conduct integrative analysis of person-specific multiple omics measurements (e.g., transcriptomics, proteomics, metabolomics) generated across multiple tissues; the multi-omic profiling should be conducted on individuals from extensively phenotyped cohorts with substantial numbers of long-lived individuals with characteristics of exceptionally healthy aging and appropriate controls.
MiamiOH OARS

PAR-18-844: Investigator Initiated Research in Computational Genomics and Data Science ... - 0 views

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    The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and biological systems. All applications should address how the methods would scale to address larger and larger data sets. Also listed under R21
MiamiOH OARS

Electronic Nicotine Delivery Systems (ENDS): Population, Clinical and Applied Preventio... - 0 views

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    The purpose of this funding opportunity announcement is to support studies on electronic nicotine delivery systems (ENDS) that examine population-based, clinical and applied prevention of disease, including etiology of use, epidemiology of use, potential risks, benefits and impacts on other tobacco use behavior among different populations.
MiamiOH OARS

RFA-RM-18-020: Limited Competition: Human Heredity and Health in Africa Consortium Bior... - 0 views

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    The purpose of this FOA is to call for U24 cooperative agreement applications that will request funding to further develop and sustain up to three H3Africa Biorepositories, building upon existing infrastructure. The H3Africa Biorepositories will continue to have the responsibility of maintaining state of the art methods and technologies for DNA collection, processing, quality control, handling, management, and storage and of providing support services needed for bio-specimen collection and dissemination in Africa. They may also propose collection and handling of specimen types including but not limited to PBMCs, plasma, serum etc.  Biorepositories will coordinate closely with H3Africa research projects and the H3Africa Bioinformatics network (H3ABioNet) to ensure responsible stewardship of high quality biological specimens linked to well-curated phenotypic and genomic data.

MiamiOH OARS

RFA-CA-18-025: Collaborative Human Tissue Network (CHTN) (UM1 Clinical Trials Not Allowed) - 0 views

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     The purpose of this Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), is to support the Cooperative Human Tissue Network (CHTN). The goal for CHTN is to collect and distribute to investigators high quality human tissue specimens to facilitate basic and early translational cancer research. For example, such specimens may be needed for scientific discovery and the development of various molecular diagnostic tests, prognostic or predictive assays. The CHTN is designed as a unique biospecimen resource in that it is based on prospective collection and distribution of samples upon specific investigators' requests. Samples to be collected from patients include pre-cancerous, cancerous, and benign neoplastic tissues, as well as specimens corresponding to non-neoplastic diseases and uninvolved tissues.

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