Sulbutiamine is a centrally acting cholinergic vitamin b analogue. One study shows sulbutiamine improve memory in rats. At this time I prefer using a combination of several b vitamins rather than relying on one vitamin b analogue. For more information on b vitamins or to purchase Vitamin b Coenzyme. Even better is to take a multivitamin that has a combination of the b vitamins along with a couple of dozen vitamins and nutrients. In most cases I think it is better to take a small amount of a number of different nutrients as opposed to a large amount of just one. Consider a very popular product that I have formulated called MultiVit-Rx.
Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, and prostate cancer risk.
Mikhak B, Hunter DJ, Spiegelman D, Platz EA, Hollis BW, Giovannucci E.
Prostate. 2007 Jun 15;67(9):911-23.
PMID: 17440943
DOI: 10.1002/pros.20570
RESULTS
No association was found Between these SNPs or their associated haplotypes and all PC suBtypes except that haplotype 2 (A-f-B) with Cdx2 A, Fok1 f, and Bsm1 B alleles and haplotype 3 (A-F-B) with Cdx2 A, Fok1 F and Bsm1 B alleles compared to the most common haplotype (A-F-B), were associated with reduced risk of aggressive PC (high stage or Gleason sum 7; P = 0.02), Both with two alleles suspected of Being low risk. Carriers of the variant Cdx2 A allele who were deficient in plasma 25-hydroxyvitamin D (15 ng/ml) compared to non-carriers with normal 25-hydroxyvitamin D, had a lower risk of total and poorly differentiated PCs (Gleason sum 7) (P for interaction = 0.02 and 0.04, respectively). Plasma 1,25-dihydroxyvitamin D deficiency (26 pg/ml) was associated with a threefold risk of poorly differentiated PC (P for interaction = 0.01) when comparing carriers of the Cdx2 A allele to non-carriers with normal 1,25-dihydroxyvitamin D.
CONCLUSION
In this population of men, none of the VDR polymorphisms studied was associated with susceptiBility to PC.
Carriers of the variant Cdx2 A allele with low plasma 25-hydroxyvitamin D may experience a reduction in risk of total and poorly differentiated prostate cancers compared to non-carriers with adequate 25-hydroxyvitamin D.
Vitamin B complex is not a single type of vitamin, But a comBination of eight types of vitamin B, which is naturally soluBle in water. Though originally considered only one type of vitamin supplements, medical scientists then found that the vitamin B complex, in fact, eight vitamins together. Vitamin B complex consists of vitamins B1, B2, B3, B5, B6, B9, B12 and vitamin comBination Choline, Inositol and Biotin.
