Study will examine the effectiveness of botulinum toxin as treatment for a variety of movement disorders. The goals of the study are to refine the technique of treatment to provide the best results, to improve the understanding of how botulinum toxin works on movement disorders, and find other conditions that may be treatable with botulinum toxin.In addition, researchers also plan to study the possible use of botulinum toxin F alone and in combination with botulinum toxin A in patients who do not respond to botulinum A toxin treatment.
Study being conducted to better understand how the brain controls movement, to learn more about movement disorders and to train movement disorder specialists.
Effect of treatment on the movement disorder will be measured by a myoclonus scale and a dystonia scale as well as by assessment of overall functional status. Response at various dosages will be compared to baseline for all patients.Safety parameters including neurological examination, blood tests and EKG will be monitored throughout the treatment period and during withdrawal of the medication.
This study is part of a series of studies that will explore how the mind and the brain work to cause episodes of uncontrollable shaking in people who have no known underlying brain or medical disorder. The study is conducted at NIH and at the Brown University Rhode Island Hospital.
Observational cohort study designed to identify the mechanisms of disease in patients with preterm labor/contractions and preterm premature rupture of membranes and to describe the relationship between clinical, biochemical, histological, biophysical parameters and the development of infant neurological disorders.
National Institute of Health - National Institute of Deafness and other Communication Disorders - Dysphagia - Definition, treatment, research, information
A preeminent non-profit professional association of pediatric neurologists in the United States, Canada, and worldwide devoted to fostering the discipline of child neurology and promoting the optimal care and welfare of children with neurological and neurodevelopmental disorders. These disorders include epilepsy, cerebral palsy, mental retardation, learning disabilities, complex metabolic diseases, nerve and muscle diseases and a host of other highly challenging conditions
Dystonias Fact Sheet at National Institute of Neurological Disorders and Stroke NINDS - what are the dystonias - Symptoms, classifications - treatment - research
Spasticity Information Page at National Institute of Neurological Disorders and Stroke NINDS - What is Spasticity -Treatment - Prognosis - Research - Clinical Trials and Organizations
Hypertonia Information Page at National Institute of Neurological Disorders and Stroke NINDS - What is hypertonia - Treatment - Prognosis - Research - Clinical Trials and Organizations
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