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Liz Richardson

Soy Alert -- Tragedy and Hype - 0 views

www.ratical.org/...soydangers.html

soy diet EED estrogenic

shared by Liz Richardson on 14 Jun 10 - Cached
  • Liz Richardson on 14 Jun 10
     
    Anti-soy campaign: what information can be trusted? Soy crops cover 72 million acres of American farmland. Much of this harvest will be used to feed chickens, turkeys, pigs, cows and salmon. Another large fraction will be squeezed to produce oil for margarine, shortenings and salad dressings. Do we ever really know how much soy we are ingesting? Many of these products are not listed as including soy.
Liz Richardson

Cellular and Physiological Effects of Soy Flavonoids - 0 views

www.benthamdirect.org/...content.php

phytoestrogens soy

shared by Liz Richardson on 08 Jun 10 - Cached
  • Liz Richardson on 08 Jun 10
     
    Abstract describes how phytoestrogens can be estrogen receptor modulators. Recent studies suggest beneficial health effects of soy and recommend increasing the intake of isoflavone-rich soy protein to the level of intake commonly used in Asian countries. Must try to open this article at the library to gain access to the free full version of the article. Vanessa - Once I access the full version I will be better able to tell you whether this is related to the other article concerning cultural differences in soy consumption and its effects on obesity.
Liz Richardson

Soy Uses - 1 views

soynutrition.com/...SoyUses.html

soy EED

shared by Liz Richardson on 22 Jun 10 - Cached
  • Liz Richardson on 22 Jun 10
     
    Are you eating soy without realizing it? Many items are made using the versatile soy bean.
Vanessa Ward

Prenatal Genistein In Soy Reduces Obesity In Offspring - DukeHealth.org - 8 views

www.dukehealth.org/...9584

genistein phytoestrogen soy endocrine EED

shared by Vanessa Ward on 04 Jun 10 - Cached
  • The agouti methylation consistently occurred throughout several germ layers of embryonic tissue, indicating that genistein acted during early embryonic development. Moreover, the methylation changes persisted into adulthood, providing the first evidence that in utero dietary genistein alters epigenetic gene regulation, coat color, and susceptibility to adult obesity in animals.
  • Liz Richardson on 04 Jun 10
     
    Vanessa - This pertains to both my study and yours. Is lack of soy consumption linked to obesity? Is it worth it to consume soy while pregnant if your child will lose risk of being fat but gain risk of being infertile?
  • Vanessa Ward on 04 Jun 10
     
    This is awesome, thanks Liz.
  • Vanessa Ward on 13 Jun 10
     
    This addresses the controversy of the role of estrogenics and the role they play in predispostion to obesity. DDE studies were positive for resulting in obesity but genistein studies show that in utero exposure results in a lower adult body weight. Both are estrogenics.
Liz Richardson

Cellular and Physiological Effects of Soy Flavonoids - 1 views

0-ehis.ebscohost.com.ksclib.keene.edu/...pdfviewer

estrogenic EED

shared by Liz Richardson on 08 Jun 10 - Cached
  • Liz Richardson on 08 Jun 10
     
    Vanessa- you may not be able to open this from home, but it is the full text version of the link I provided earlier. Soy isoflavones are felt to protect against different cancers, cardiovascular disease, and bone loss, and possibly weight gain.
Vanessa Ward

San Francisco Medical Society | The Weight of Evidence - 0 views

www.sfms.org/...Template.cfm

SFMS Blumberg Grun obesity epidemic endocrine disruption EDCs obesity

shared by Vanessa Ward on 11 Jun 10 - Cached
  • “leading to neglect of other plausible mechanisms and well-intentioned but potentially ill-founded proposals for reducing obesity rates”
  • Since publication of that review, substantial evidence has emerged that increases the plausibility of one of the alternative mechanisms suggested by Keith et al: disruption of weight regulation by endocrine-disrupting chemicals (EDCs) in the environment.
  • Concerns about the potential contribution of EDCs to childhood obesity build from two considerations, one out of human biology and the other from animal experiments
  • ...7 more annotations...
  • Prior
  • toxicologists were concerned more with weight loss, which was seen as an adverse outcome.
  • Many of these chemicals alter the behavior of specific genes that are involved in determining the number of fat cells (adipocytes) an individual will have as an adult.
  • he list of contaminants implicated by animal studies is substantial, including several estrogenic EDCs such as DES, bisphenol A, soy phytoestrogens
  • Almost no human data are available to test the obesogen hypothesis in people. No epidemiological evidence exists, because the hypothesis is so new
  • One in vitro experiment, however, has demonstrated that exposure to obesogens increases the rate of conversion of human stem cells to adipocytes (Kirchner et al 2010), confirming the validity of the basic mechanism and the relevance of the animal studies to people.
  • That would be a big win for medicine and public health.
  • Vanessa Ward on 11 Jun 10
     
    San Francisco Medical Society discusses the possible relationship between chemical exposure and the obesity epidemic.
Vanessa Ward

PLoS Biology: The Toxic Origins of Disease - 0 views

www.plosbiology.org/...journal.pbio.0050193

obesity endocrine origins of disease DES Blumberg Grun obesogen

shared by Vanessa Ward on 11 Jun 10 - Cached
  • During embryonic development, steroid hormones like estrogen control gene-expression programs to coordinate cell differentiation, growth, organogenesis, and metabolism.
  • “The moment we published something on bisphenol A, the chemical industry went out and hired a number of corporate laboratories to replicate our research. What was stunning about what they did . . . was they hired people who had no idea how to do the work.”
  • “whole-animal toxicological studies,” which look at different endpoints than the more mechanistic studies do, Hughes says. “That doesn't let you look at changes in gene expression, changes in epigenetic control of gene expression.
  • ...5 more annotations...
  • “I can tell you simply by the size of the animal which is DES-exposed and which isn't.”
  • “We found out that brain is a target, bone is a target . . . and now the new target is adipocytes.”
  • When he removed all the soy-derived plant estrogens from the mother's diet, he was astonished to see endogenous estradiol levels in the fetus rise, and the offspring become “horrifically obese.
  • Adding the weak plant estrogens back in the diet suppressed the far more potent endogenous estradiol, he discovered, by inhibiting an enzyme required to make it.
  • Recent evidence suggests that a class of ubiquitous environmental pollutants called organotins can also stimulate adipogenesis and interfere with energy balance
  • Vanessa Ward on 11 Jun 10
     
    This was one of the first articles that I looked in depth at and pretty much read all of. It presents some of the original research done on the effects Bisphenol-A on reproductive development and mammary gland formamation and how in the process led to a noticeable pattern between exposure and weight gain. The study of obesogens is a new field that was in a way accidentally discovered. It has been hypothesized that estrogen causes embryonic cells to develop into fat cells through a process called adipogenesis by chemicals called organotins. New research to support this is addressed in this article.
Liz Richardson

USDA-Iowa State University Database on the Isoflavone Content of Foods - 1999 - 1 views

www.nal.usda.gov/...isoflav.html

isoflavone soy nutrition

shared by Liz Richardson on 04 Jun 10 - Cached
  • Liz Richardson on 04 Jun 10
     
    What foods should be avoided during pregnancy to insure fertility of the unborn child? What foods should we not be eating to insure our own health and well-being?
  • Liz Richardson on 04 Jun 10
     
    Do you want to know what you are ingesting???
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