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wow, a big step in genomics...!

But isn't it just yet another word abuse? From what I understand, they just synthesised a genome identical to the one of an existing bacteria... while undoubtedly nice work, this is *very* far from "creating life from scratch"... The fact that you are able to copy something, doesn't mean you understand how it works...

well of course we are far from engineering specific functions, and this is just a copy of a function that already existed. However it is quite impressive and the first time it is done. And the challenge here is not really to "copy" the ADN, but the fact that it works... in other words it is not because you copy the ADN identically that the phenotype (traduction of the ADN) will be the same, which is the case in this experiment.

These people want to construct a synthetic human genome

Look at this! Seems that we are as close to the bonobos as we are to the chimpanzees If only we resolved more to their ways of getting rid of stress (sex) more than using the chimpanzees' (aggression)...

From the statistical analysis of nucleosome positioning data for chromosome III of S. cerevisiae, we demonstrate that long-range correlations (LRC) in the genomic sequence strongly influence the organization of nucleosomes.

An incresingly popular scientific enome re-writting tool. Might prevent future generations from being born with some types of disorders or disabilities! Also, for fun, can be looked at one step closer to having a real wolverine..

"Chinese team uses CRISPR to genetically modify human embryo" http://medicalxpress.com/news/2016-04-chinese-team-crispr-genetically-human.html?utm_source=nwletter&utm_medium=email&utm_campaign=weekly-nwletter

"For the first time, researchers have determined virtually the entire genome of a fetus using only a blood sample from the pregnant woman and a saliva specimen from the father."

disruptive!

Exciting new technique in genetic engineering

Nature: Scientist have found a plant that has a very small genome because it manages to remove junk DNA.

The spreadsheet software Microsoft Excel, when used with default settings, is known to convert gene names to dates and floating-point numbers. A programmatic scan of leading genomics journals reveals that approximately one-fifth of papers with supplementary Excel gene lists contain erroneous gene name conversions. The reason why you shouldn't use Excel (or Numbers or OpenOffice or ...) without knowing what it actually really does!

A frog study provides the strongest evidence yet that a father's lifestyle may affect the next generation, via chemical tags that change gene activity SPERM pass on more than just their DNA. Chemical switches attached to the genomes of sperm - known as epigenetic tags - have been shown to alter the next generation for the first time.

copy paste church marries first couple :-)

I just thought: who is the author of my genome? Me? My parents? And if it's my parents, could they try to prevent me from reproducing based on copyright laws?

Looks like we are all spider men and women :)

scary but very likely development ... blessing in disguise?

scary but very likely development ... blessing in disguise?

they have found Christina's dog !!

next step - just in time for our workshop ... maybe for >Tobias to read before ...

Nice approach to generate healthy skin and to patch parts or to replace the overall human skin. Next step - clinical studies.

Jeremy England, a 31-year-old assistant professor at the Massachusetts Institute of Technology, has derived a mathematical formula that he believes explains this capacity. The formula, based on established physics, indicates that when a group of atoms is driven by an external source of energy (like the sun or chemical fuel) and surrounded by a heat bath (like the ocean or atmosphere), it will often gradually restructure itself in order to dissipate increasingly more energy. This could mean that under certain conditions, matter inexorably acquires the key physical attribute associated with life. The simulation results made me think of Jojo's attempts to make a self-assembling space structure. Seems he may have been on the right track, just not thinking big enough

:-P Thanks Thijs... I do not agree with the premise of the article that a possible correlation of energy dissipation in living systems and their fitness means that one is the cause for the other - it may just be that both go hand-in-hand because of the nature of the world that we live in. Maybe there is such a drive for pre-biotic systems (like crystals and amino acids), but once life as we know it exists (i.e., heredity + mutation) it is hard to see the need for an amendment of Darwin's principles. The following just misses the essence of Darwin: "If England's approach stands up to more testing, it could further liberate biologists from seeking a Darwinian explanation for every adaptation and allow them to think more generally in terms of dissipation-driven organization. They might find, for example, that "the reason that an organism shows characteristic X rather than Y may not be because X is more fit than Y, but because physical constraints make it easier for X to evolve than for Y to evolve." Darwin's principle in its simplest expression just says that if a genome is more effective at reproducing it is more likely to dominate the next generation. The beauty of it is that there is NO need for a steering mechanism (like maximize energy dissipation) any random set of mutations will still lead to an increase of reproductive effectiveness. BTW: what does "better at dissipating energy" even mean? If I run around all the time I will have more babies? Most species that prove to be very successful end up being very good at conserving energy: trees, turtles, worms. Even complexity of an organism is not a recipe for evolutionary success: jellyfish have been successful for hundreds of millions of years while polar bears are seem to be on the way out.

"A new study of chickens overturns the popular assumption that evolution is only visible over long time scales. By studying individual chickens that were part of a long-term pedigree, the scientists led by Professor Greger Larson at Oxford University's Research Laboratory for Archaeology, found two mutations that had occurred in the mitochondrial genomes of the birds in only 50 years."