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Millennium Core issues related to the case: * To establish a formal set up in the organisation and a productive relationship with Millennium's management team while maintaining its entrepreneurial vision and culture. * To bring Millennium back to profitability by moving it from its R&D roots to a more commercially-focused platform. * To regain credibility with the investment community. * To reallocate the resources of Millennium between its commercial and R&D platforms. * To optimize current commercial opportunities without jeopardizing future product development. * Informal review process and compensation system. * Lack of employees in commercial wing of Millennium. * Ignorance of competition faced by the company with regard to its products. * Failure due to marketing philosophy of Millennium. * Losses due to failure of some alliances. * Lack of competent employees at executive level mainly in R&D. Analysis of data for the root cause/s of the problem Millennium's organizational structure and processes had always been more informal than those of larger companies. It was organized around its people. Employees relied on informal committees and ad-hoc systems throughout the firm to help guide the business and coordinate operations. A lot of people resisted or resented the change in culture when Levin began to professionalize executive meetings when Millennium prepared to launch Velcade commercially and to restructure its business. There was Frustration among employees due to informal review process and biasness in terms of deciding over compensation policy. Over time some disadvantages of the alliances began to manifest themselves. Failure occurred in acquisition of CORE by Millennium. Huge cost incurred in restructuring process in 2003. Millennium fails to consider the competition Integrilin faced in the market. Marketing philosophy of Millennium that markets were won through good science and clinical data so products based on good data woul

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