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Alison Prodzinski

How Pigs on Antibiotics Are Making Superbugs Stronger | Popular Science - 0 views

  • new research suggests it’s the animals, and the drugs we feed them
  • MRSA started out as a drug-defeatable bug and then transferred into the pig population, where it developed resistance to two common forms of antibiotics
  • “[It’s] like watching the birth of a superbug,”
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  • humans have supplied a strong force through the excessive use of antibiotic drugs in farm animal production,
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    MSRA could be defeated when first discovered. However, it was transferred to the pig population and went crazy after that. Humans over immunize animals and make super-bugs from inappropriate and overuse of antibiotics.  New tests are being done with bacteria being injected into other hosts - which then can be used to kill MRSA. This method could find new and natural antibiotics that could fight various forms of drug-resistant superbugs!
Katelyn Madigan

Superbugs may have a soft spot, after all - 1 views

  • identified a weakness in at least one superbug that scientists may be able to medically exploit
  • discovered that two proteins already present in E. coli cells -- RbfA and KsgA -- need to be in balance with each other in order for ribosomes to function
  • RbfA does not exist in humans
Tyrell Varner

CDC warning of superbug 'nightmare' - Canon City Daily Record - 0 views

    • Tyrell Varner
       
      This is pretty much exactly what we covered in lecture. I just wonder how far/severe the outcome will be until harsh regulation takes place?
  • Overuse and improper use of antibiotics over the years, both in the medical community and the livestock industry, has led to an increase in the number of bacteria that are drug-resistant.
  • At least 80 percent of antibiotics used annually in the U.S. are used routinely in livestock to promote growth.
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  • Food and Drug Administration
  • banned only one type of antibiotic in livestock and urged the industry to voluntarily limit antibiotic use to promote growth.
Casey Finnerty

How Scientists Stopped Klebsiella Pneumoniae: Deadly Superbug Killed 6 At NIH Clinical ... - 1 views

  • 18 people harbored the dangerous germ, and six died of bloodstream infections from it. Another five made it through the outbreak only to die from the diseases that brought them to NIH's world-famous campus in the first place.
  • Infections at health care facilities are one of the nation's leading causes of preventable death, claiming an estimated 99,000 lives a year.
  • KPC has emerged over the past decade to become a fast-growing threat in intensive care units, spreading easily between very ill people and killing half of those it sickens.
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  • KPC was transmitted three separate times from Patient No. 1, and then spread more widely.
  • Test after test never found the bug on hospital workers' hands.
  • "There's better technology becoming available for your hospital to prevent these bacteria from spreading, and this is what you should expect from your hospital," he said.
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    I agree that it is wise to broaden the scope of infection control to custodial workers, since they would often be in contact with several of the inanimate objects in the room. This is really shown when they were unable to find the superbug on the "hospital workers' hands." Did they test everyone?
Casey Finnerty

Hospitals Fight To Stop Superbugs' Spread : NPR - 0 views

  • CONAN: Well, is there something that - some things that every hospital or every clinic should be doing in order to minimize the risk? PERENCEVICH: I think one of the most important things they can do is make sure their microbiology lab is able to detect these strains.
Emma Radzak

Superbugs: Unmasking the Threat - 0 views

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    More information about superbugs summarizing how they become resistant to antibiotics, the new classes of antibiotics created to combat them, and what we can do to prevent antibiotic resistance. In the article it listed 12 steps to prevent antibiotic resistance, where it stresses the importance of vaccinations, timely diagnosis, limiting the antibiotics being used, and "breaking the chain" (staying at home when your sick, and washing your hands).
Nellie Bogunovic

Drugs to Fight Deadly Superbugs in Short Supply - 0 views

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    With antibiotic resistance looming, the failure of drug companies to develop new drugs to fight gram-negative bacteria could potentially lead to millions of deaths just from a common cold or from the flu. Drug companies cannot turn out new antimicrobials fast enough, and the ones that they do get out to the public cost billions of dollars.
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    Scary to think that we're all at risk!
Emma Radzak

Hospitals see surge of superbug-fighting products - 0 views

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    It's amazing to think that even though there is no widely-accepted evidence that these inventions have prevented infections or death, hospitals are still spending over $125,000 per machine to attempt to ensure cleanliness.
Megan Rasmussen

Doctors warn of 'aggressive' new sexually-transmitted superbug - 0 views

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    Gonorrhea HO41 was discovered two years ago and is not only a very resistant strain of gonorrhea but it can cause septic shock leading to death all within a couple of days
Nellie Bogunovic

Hospitals See Surge of Superbug-Fighting Products - 0 views

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    Reminds me of when Dr. Finnerty told us about the sinks they had at Cornell that weren't attached to the walls so bacteria wouldn't accumulate in the seam between the sink and wall!
Katelyn Madigan

Novel approaches needed to end growing scourge of 'superbugs' - 1 views

    • Katelyn Madigan
       
      How common are intestinal infections compared to the more well-known UTIs?
  • development of new antibiotics to treat these infections is plummeting
    • Katelyn Madigan
       
      Unable to keep up with the rapidly mutating strains?
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  • greater disinfection and less usage of invasive materials than can transmit antibiotic-resistant bacteria into the body
  • moderate the inflammatory response to infection or that limit microbial growth by blocking access to host resources without attempting to kill microbes.
    • Katelyn Madigan
       
      Are there multiple ways to provide resistance to the host cell? Would this be done only after an infection, so as to just limit the damage done?
  • If we want a long-term solution, the answer is not incremental tweaking of these policies and processes. Novel approaches, based on a reconceptualization of the nature of resistance, disease, and prevention, are needed.
    • Katelyn Madigan
       
      Well stated.
  • infect more than 2 million Americans every year and kill more than 100,000 annually,
Casey Finnerty

A superbug that resisted 26 antibiotics | Minnesota Public Radio News - 0 views

  • a woman in Nevada who died of an incurable infection, resistant to all 26 antibiotics available in the U.S. to treat infection.
  • as people cross borders and board airplanes, the bacteria spread in the same way that brought CRE to Reno.
  • all hospitals should double down on preventive efforts, including a travel history.
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  • But in this case, there was no effective antibiotic. "And we're going to see more of these, from a drip, drip, drip of cases to a steady drizzle to a rainstorm," predicts Johnson. "It's scary, but it's good to get scared if that motivates action."
  • The action needed is to use antibiotics wisely, in people and in animals, so strains of bacteria don't get a chance to develop resistance, says Johnson. And to continue research into development of new antibiotics.
Casey Finnerty

Scientists may have worked out how to defeat antibiotic-resistant superbugs - 0 views

  • It turns out that the reason bugs like Staphylococcus aureus are capable of resisting antibiotics is because they develop a lipid-based outer membrane.
    • Casey Finnerty
       
      S. aureus is Gram+, it does not possess an outer membrane!
    • Casey Finnerty
       
      Also, not all antibiotic resistance results from having an outer membrane.
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