susceptibilities of the multiple-drug resistant strain of S. aureus to deuteroporphyrin and to hemin were tested. The effect of the addition of porphyrins, separately and together, to a logarithmic culture was determined from the viable count of S. aureus over an 8 h period.
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The use of porphyrins for eradication of Staphylococcus aureus in burn wound infections... - 0 views
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This work confirmed that a deuteroporphyrin-hemin complex is a potent killer of a multiple-antibiotic resistant S. aureus in culture
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This complex was able to reduce the number of bacteria by six orders of magnitude within 8 h. By using this complex, which is light independent, we have overcome the problem of light penetration to the subeschar space.
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Porphyrins represent a potential treatment for burn wound infections
BMC Microbiology | Full text | In vivo killing of Staphylococcus aureus using a light-a... - 0 views
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This was the first study to use a light-activated substance to destroy MRSA in wounds
Photodynamic therapy for Staphylococcus aureus infected burn wounds in mice - 0 views
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The growing resistance of pathogenic microorganisms against antimicrobial agents has generated a search for alternative treatments for localized infections.
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In this study we have demonstrated that it is possible to rapidly photoinactivate S. aureus when present in a burn wound with PTMPP as PS
Using 'Bacteria-Eaters' to Prevent Infections On Medical Implant Materials - 0 views
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They describe attachment of phages to the surfaces of materials like those used in implanted medical devices, and evidence that the phages remain active, killing E. coli and Staphylococcus aureus. Those bacteria cause the most common hospital-acquired infections.
Staph Germs Hide Out In The Hidden Recesses Of Your Nose : Shots - Health News : NPR - 0 views
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The fact that staph germs are hanging out in remote precincts of the nose may explain why efforts to kill off the germs on carriers before elective surgery can fail, Relman thinks. The voyage up the nose also revealed that staph thrived only when another bacterial species, C. pseudodiptheriticum, was in short supply. It could be that this second microbe produces substances that keep staph at bay.
Scientists may have worked out how to defeat antibiotic-resistant superbugs - 0 views
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It turns out that the reason bugs like Staphylococcus aureus are capable of resisting antibiotics is because they develop a lipid-based outer membrane.
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S. aureus is Gram+, it does not possess an outer membrane!
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Also, not all antibiotic resistance results from having an outer membrane.
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