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susceptibilities of the multiple-drug resistant strain of S. aureus to deuteroporphyrin and to hemin were tested. The effect of the addition of porphyrins, separately and together, to a logarithmic culture was determined from the viable count of S. aureus over an 8 h period.

This work confirmed that a deuteroporphyrin-hemin complex is a potent killer of a multiple-antibiotic resistant S. aureus in culture

This complex was able to reduce the number of bacteria by six orders of magnitude within 8 h. By using this complex, which is light independent, we have overcome the problem of light penetration to the subeschar space.

The growing resistance of pathogenic microorganisms against antimicrobial agents has generated a search for alternative treatments for localized infections.

In this study we have demonstrated that it is possible to rapidly photoinactivate S. aureus when present in a burn wound with PTMPP as PS

Further research along these lines could lead to an objective measure of physical pain, though that's still a long ways away.

Right now, if a doctor wants to measure or record someone's pain, she'll generally just ask her patient about it, or ask her patient to rate his pain from 1 to 10. That will always be a very important part of diagnosis, Wager says, but having a less subjective measure could nevertheless help. Some people, such as very young, very old or certain disabled people, can't communicate well. Others may underreport their pain—or are less likely to be believed.

Using this pain signature, they were then able to evaluate people's pain in response to particular levels of heat with 90 to 100 percent accuracy