Man's Genome From 45,000 Years Ago Is Reconstructed - NYTimes.com - 0 views
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Scientists have reconstructed the genome of a man who lived 45,000 years ago, by far the oldest genetic record ever obtained from modern humans. The research, published on Wednesday in the journal Nature, provided new clues to the expansion of modern humans from Africa about 60,000 years ago, when they moved into Europe and Asia.
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In December, they published the entirety of a Neanderthal genome extracted from a single toe bone. Comparing Neanderthal to human genomes, Dr. Paabo and his colleagues found that we share a common ancestor, which they estimated lived about 600,000 years ago.
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They found that his DNA was more like that of non-Africans than that of Africans. But the Ust’-Ishim man was no more closely related to ancient Europeans than he was to East Asians.He was part of an earlier lineage, the scientists concluded — a group that eventually gave rise to all non-African humans.
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The Ust’-Ishim man’s genome suggests he belonged to a group of people who lived after the African exodus, but before the split between Europeans and Asians.
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By comparing the Ust’-Ishim man’s long stretches of Neanderthal DNA with shorter stretches in living humans, Dr. Paabo and his colleagues estimated the rate at which they had fragmented. They used that information to determine how long ago Neanderthals and humans interbred.
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The findings raised questions about research suggesting that humans in India and the Near East dated back as far as 100,000 years ago. Some scientists believe that humans expanded out of Africa in a series of waves.
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the new study offered compelling evidence that living non-Africans descended from a group of people who moved out of Africa about 60,000 years ago.Any humans that expanded out of Africa before then probably died out, Mr. Stringer said.