Calcium plus vitamin D supplementation and the risk of breast cancer.
Chlebowski RT, Johnson KC, Kooperberg C, Pettinger M, Wactawski-Wende J, Rohan T, Rossouw J, Lane D, O'Sullivan MJ, Yasmeen S, Hiatt RA, Shikany JM, Vitolins M, Khandekar J, Hubbell FA; Women's Health Initiative Investigators.
J Natl Cancer Inst. 2008 Nov 19;100(22):1581-91. Epub 2008 Nov 11.
PMID: 19001601
ncident invasive breast cancer, geographic location of residence, and reported average time spent outside.
Millen AE, Pettinger M, Freudenheim JL, Langer RD, Rosenberg CA,
Mossavar-Rahmani Y, Duffy CM, Lane DS, McTiernan A, Kuller LH, Lopez AM, Wactawski-Wende J.
Cancer Epidemiol Biomarkers Prev. 2009 Feb;18(2):495-507. Epub 2009 Feb 3.
PMID: 19190147
doi: 10.1158/1055-9965.EPI-08-0652
In conclusion, region of residence and geographic solar irradiance are not consistently related to risk of breast cancer and may not be sufficient proxy measures for sunlight/vitamin D exposure. The observed association between time spent outside and breast cancer risk support the hypothesis that vitamin D may protect against breast cancer.
Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of incident ovarian cancer.
Tworoger SS, Lee IM, Buring JE, Rosner B, Hollis BW, Hankinson SE.
Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):783-8.
PMID: 17416771
doi: 10.1158/1055-9965.EPI-06-0981
Overall, our results do not suggest that plasma vitamin D levels are associated with risk of ovarian cancer. However, we observed significant associations in some subgroups, which should be evaluated further in other studies because increasing vitamin D intake is an easy preventive measure to adopt.
Prognostic effects of 25-hydroxyvitamin D levels in early breast cancer.
Goodwin PJ, Ennis M, Pritchard KI, Koo J, Hood N.
J Clin Oncol. 2009 Aug 10;27(23):3757-63. Epub 2009 May 18.
PMID: 19451439
DOI: 10.1200/JCO.2008.20.0725
Conclusion Vitamin D deficiency may be associated with poor outcomes in breast cancer.
Vitamin D deficiency is associated with BV and may contribute to the strong racial disparity in the prevalence of BV.
Maternal vitamin D deficiency is associated with bacterial vaginosis in the first trimester of pregnancy.
Bodnar LM, Krohn MA, Simhan HN.
J Nutr. 2009 Jun;139(6):1157-61. Epub 2009 Apr 8.
PMID: 19357214
doi:10.3945/jn.108.103168
Vitamin D Deficiency in the Morbidly Obese.
Buffington C, Walker B, Cowan GS Jr, Scruggs D.
Obes Surg. 1993 Nov;3(4):421-424.
PMID: 10757956
These data suggest that low vitamin D may be associated with obesity per se. Hypovitaminosis D, when it is found in post-bariatric surgery patients, may not be caused by the surgery since it may have been present to some degree pre-operatively.
Relationship between low ultraviolet B irradiance and higher breast cancer risk in 107 countries.
Mohr SB, Garland CF, Gorham ED, Grant WB, Garland FC.
Breast J. 2008 May-Jun;14(3):255-60. Epub 2008 Apr 17.
PMID: 18422861
DOI: 10.1111/j.1524-4741.2008.00571.x
There was a protective effect of UVB irradiance on risk of breast cancer that was independent of fertility rate, proportion of the population overweight, alcohol intake, animal energy intake, and other covariates.