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Correlation of symptoms with vitamin D deficiency and symptom response to cholecalciferol treatment: a randomized controlled trial. Arvold DS, Odean MJ, Dornfeld MP, Regal RR, Arvold JG, Karwoski GC, Mast DJ, Sanford PB, Sjoberg RJ. Endocr Pract. 2009 May-Jun;15(3):203-12. PMID: 19364687 Conclusions: Compared with participants in the placebo group, patients in the treatment group showed mild short-term improvement in the overall fibromyalgia impact score, but did not show significant improvement in most musculoskeletal symptoms or in activities of daily living.

Effects of vitamin D supplementation on symptoms of depression in overweight and obese subjects: randomized double blind trial. Jorde R, Sneve M, Figenschau Y, Svartberg J, Waterloo K. J Intern Med. 2008 Dec;264(6):599-609. Epub 2008 Sep 10. PMID: 18793245 Conclusions. It appears to be a relation between serum levels of 25(OH)D and symptoms of depression. Supplementation with high doses of vitamin D seems to ameliorate these symptoms indicating a possible causal relationship.

Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese. Pan A, Lu L, Franco OH, Yu Z, Li H, Lin X. J Affect Disord. 2009 Nov;118(1-3):240-3. Epub 2009 Feb 27. PMID: 19249103 doi:10.1016/j.jad.2009.02.002 Conclusions Depressive symptoms are not associated with 25(OH)D concentrations in middle-aged and elderly Chinese. Further prospective studies are required to determine whether they are correlated.

Vitamin D and depressive symptoms in women during the winter: a pilot study. Shipowick CD, Moore CB, Corbett C, Bindler R. Appl Nurs Res. 2009 Aug;22(3):221-5. PMID: 19616172 doi:10.1016/j.apnr.2007.08.001 ESULTS: Vitamin D supplementation was associated not only with an increase in the serum D levels by an average of 27 ng/ml but also with a decline in the BDI-II scores of an average of 10 points. DISCUSSION: This study suggests that supplemental vitamin D3 reduces depressive symptoms.

Association between serum 25-hydroxyvitamin D and depressive symptoms in Japanese: analysis by survey season A Nanri, T Mizoue, Y Matsushita, K Poudel-Tandukar, M Sato, M Ohta, N Mishima European Journal of Clinical Nutrition (19 August 2009) doi:10.1038/ejcn.2009.96 Short Communication

"For more than 80 years, scientists have known that vitamin D is important for building bones. And for most of those 80 years, people thought this was the only thing it was good for. In the past decade, however, we've learned two important things about vitamin D: it appears to have many other important health effects, and many Americans don't get enough of it. In 2008, new research pointed to a vitamin D deficiency as a possible contributing factor in heart disease. And the suspected link between vitamin D deficiency and cancer grew even stronger. This surely will spur much new research in 2009. Why is vitamin D deficiency so common? The vitamin is made in our skin when sunlight strikes it. Many Americans-especially those who live in the northern part of the country, are elderly or have dark skin-don't soak up enough sun. And the vitamin isn't found in many foods. The main sources are fatty fish (such as salmon, mackerel, herring and sardines) and milk, cereal and juices that have been fortified with it. Vitamin D deficiency often is unsuspected because it causes no direct symptoms; like high blood pressure, it does its damage silently."

"Posted Tue Nov 17, 2009 4:01pm AEDT Updated Tue Nov 17, 2009 4:27pm AEDT Researchers are advising people with MS to take safe levels of vitamin D supplements. Researchers are advising people with MS to take safe levels of vitamin D supplements. (ABC News: Giulio Saggin, file photo) * Audio: New research shows Vitamin D may slow the progress of MS (The World Today) Australian scientists have found that Vitamin D may slow the progression of multiple sclerosis (MS). Figures showing that people living in Tasmania are seven times more likely to develop MS than Queenslanders had suggested a link between sunlight exposure and the disease. "

Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese. Pan A, Lu L, Franco OH, Yu Z, Li H, Lin X. J Affect Disord. 2009 Feb 25. [Epub ahead of print] PMID: 19249103 doi:10.1016/j.jad.2009.02.002    

"In 1995 my son received the devastating diagnosis of MS. Having been a research scientist for 30 years, I decided to plunge into the scientific literature for MS to determine the most likely factors which cause MS and to use this information to develop an effective therapy for my son. Notably, many people are having great success in halting or greatly slowing MS with nutritional strategies; many Testimonials are available. I am most pleased to report that my son remains in excellent health with no MS symptoms. I discovered abundant scientific evidence that indicates that various nutritional factors potentially play major roles in the onset and progression of MS. Strangely, this information was not being made available to persons with MS by doctors nor by established MS charities."

ScienceDaily (Mar. 18, 2009) - A lack of Vitamin D, due to reduced sunlight, has been linked to depression and the symptoms of Seasonal Affective Disorder (SAD), but research by the University of Warwick shows there is no clear link between the levels of vitamin D in the blood and depression.

Stress fractures in the Israeli defense forces from 1995 to 1996. Givon U, Friedman E, Reiner A, Vered I, Finestone A, Shemer J. Clin Orthop Relat Res. 2000 Apr;(373):227-32. PMID: 10810481 Serum levels of bone specific alkaline phosphatase and osteocalcin were elevated in patients with high grade stress fractures compared with control subjects with no symptoms: 37.6 versus 26.2 units/L, and 10.8 versus 8.8 ng/mL, respectively. Levels of 25-hydroxy vitamin D were lower in patients with high grade stress fractures (25.3 ng/mL) than in control subjects (29.8 ng/mL). This study revealed that several parameters can distinguish soldiers with high grade stress fractures, but their predictive value and precise pathogenetic role remain unclear.