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Seriously ill Covid-19 patients treated with hydroxychloroquine and chloroquine were more likely to die or develop dangerous heart arrhythmias, according to a large observational study published Friday in the medical journal The Lancet.

Researchers looked at data from more than 96,000 Covid-19 patients from 671 hospitals. All were hospitalized from late December to mid-April and had died or been discharged by April 21. Just below 15,000 were treated with the antimalarial drugs hydroxychloroquine or chloroquine, or one of those drugs combined with an antibiotic.

Those treatments were linked with a higher risk of dying in the hospital, the study found.

“Expertise is a tricky thing,” said Leigh Tost, an associate professor of management and organization at the University of Southern California Marshall School of Business. “To take advice from someone is to agree to be influenced by them.” Sometimes when people don’t take advice, they’re rejecting the idea of being controlled by the advice-giver more than anything.

Researchers identified three factors that determine whether input will be taken to heart. People will go along with advice if it was costly to attain and the task is difficult (think: lawyers interpreting a contract). Advice is also more likely to be taken if the person offering counsel is more experienced and expresses extreme confidence in the quality of the advice (doctors recommending a treatment, for example). Emotion plays a role, too: Decision makers are more likely to disregard advice if they feel certain about what they’re going to do (staying with a dud boyfriend no matter what) or they’re angry (sending an ill-advised text while fuming).

Make sure you’re actually being asked to give counsel. It’s easy to confuse being audience to a venting session with being asked to weigh in. Sometimes people just want to feel heard.

United States Postal Service workers, who are still delivering and sorting mail at distribution centers around the country even as millions of Americans telecommute, are worried that they may not have the protection -- or even the funding -- they will need to keep delivering mail for months longer.

Reports have popped up across the country where postal workers say they don't have hand sanitizer, gloves or masks, and are being told to work despite illnesses and are looking to community donations to address supply shortfalls.

Rep. Mary Gay Scanlon, a Pennsylvania Democrat, said postal workers in her region have said they don't have hand sanitizer or materials needed to keep post offices disinfected.

Social media platforms like Facebook, YouTube and Twitter generate revenue by using detailed behavioral information to direct ads to individual users.

this bland description of their business model fails to convey even a hint of its profound threat to the nation’s political and social stability.

legislators in Congress to propose the breakup of some tech firms, along with other traditional antitrust measures. But the main hazard posed by these platforms is not aggressive pricing, abusive service or other ills often associated with monopoly.

Padilla laid out an indictment of his field. “If one were intentionally to design a discipline whose institutional organs and gatekeeping protocols were explicitly aimed at disavowing the legitimate status of scholars of color,” he said, “one could not do better than what classics has done.”

Padilla believes that classics is so entangled with white supremacy as to be inseparable from it. “Far from being extrinsic to the study of Greco-Roman antiquity,” he has written, “the production of whiteness turns on closer examination to reside in the very marrows of classics.”

Rather than kowtowing to criticism, Williams said, “maybe we should start defending our discipline.” She protested that it was imperative to stand up for the classics as the political, literary and philosophical foundation of European and American culture: “It’s Western civilization. It matters because it’s the West.” Hadn’t classics given us the concepts of liberty, equality and democracy?

The problem for many people is that we cannot point to the underlying biological bases of most psychiatric disorders. In fact, we are nowhere near understanding them as well as we understand disorders of the liver or the heart.

Facebook is not just any corporation. It reached trillion-dollar status in a single decade by applying the logic of what I call surveillance capitalism — an economic system built on the secret extraction and manipulation of human data

Facebook and other leading surveillance capitalist corporations now control information flows and communication infrastructures across the world.

These infrastructures are critical to the possibility of a democratic society, yet our democracies have allowed these companies to own, operate and mediate our information spaces unconstrained by public law.

To test Darwin’s theory, the researchers quizzed people on several topics, such as grammar, logical reasoning and humor. After each test, they asked the participants how they thought they did. Specifically, participants were asked how many of the other quiz-takers they beat.

Dunning was shocked by the results, even though it confirmed his hypothesis. Time after time, no matter the subject, the people who did poorly on the tests ranked their competence much higher. On average, test takers who scored as low as the 10th percentile ranked themselves near the 70th percentile. Those least likely to know what they were talking about believed they knew as much as the experts.

Dunning and Kruger’s results have been replicated in at least a dozen different domains: math skills, wine tasting, chess, medical knowledge among surgeons and firearm safety among hunters.

Everyone—even the most privileged among us—has circumstances they would like to change in their life.

How might you improve the situation? Your answer might be, “I should move, get a new job, and meet new people.” In other words, you should change the outside world to make it better for you.

Between the conditions around you and your response to them is a space. In this space, you have freedom. You can choose to try remodeling the world, or you can start by changing your reaction to it.

if all of those bad presentations really led to broad societal ills, the proof is hard to find.

Some scientists have tried to take a formal measure of the alleged PowerPoint Effect, asking whether the software really influences our ability to process information. Sebastian Kernbach, a professor of creativity and design at the University of St. Gallen, in Switzerland, has co-authored multiple reviews synthesizing this literature. On the whole, he told me, the research suggests that Tufte was partly right, partly wrong. PowerPoint doesn’t seem to make us stupid—there is no evidence of lower information retention or generalized cognitive decline, for example, among those who use it—but it does impose a set of assumptions about how information ought to be conveyed: loosely, in bullet points, and delivered by presenters to an audience of passive listeners. These assumptions have even reshaped the physical environment for the slide-deck age, Kernbach said: Seminar tables, once configured in a circle, have been bent, post-PowerPoint, into a U-shape to accommodate presenters.

When I spoke with Kernbach, he was preparing for a talk on different methods of visual thinking to a group of employees at a large governmental organization. He said he planned to use a flip chart, draw on blank slides like a white board, and perhaps even have audience members do some drawing of their own. But he was also gearing up to use regular old PowerPoint slides. Doing so, he told me, would “signal preparation and professionalism” for his audience. The organization was NASA.

The company you work for may want to know. Some corporate employers fear that employees could leak information, allow access to confidential files, contact clients inappropriately or, in the extreme, bring a gun to the office.

at times using behavioral science tools like psychology.

But in spite of worries that workers might be, reasonably, put off by a feeling that technology and surveillance are invading yet another sphere of their lives, employers want to know which clock-punchers may harm their organizations.

the brief return of one of my favorite discursive topics—are the kids all right?—in one of my least-favorite variations: why shouldn’t each of them have a smartphone and tablet?

One camp says yes, the kids are fine

complaints about screen time merely conceal a desire to punish hard-working parents for marginally benefiting from climbing luxury standards, provide examples of the moral panic occasioned by all new technologies, or mistakenly blame screens for ill effects caused by the general political situation.

In an academic career that included more than two decades as a professor in the philosophy department of the University of Toronto, following appointments at Cambridge and Stanford, Professor Hacking’s intellectual scope seemed to know no bounds. Because of his ability to span multiple academic fields, he was often described as a bridge builder.

“Ian Hacking was a one-person interdisciplinary department all by himself,” Cheryl Misak, a philosophy professor at the University of Toronto, said in a phone interview. “Anthropologists, sociologists, historians and psychologists, as well as those working on probability theory and physics, took him to have important insights for their disciplines.”

Professor Hacking wrote several landmark works on the philosophy and history of probability, including “The Taming of Chance” (1990), which was named one of the best 100 nonfiction books of the 20th century by the Modern Library.

Congress needs to develop a way of better funding the F.D.A. review process. Perhaps a small excise tax could be levied on over-the-counter sales or fees assessed to makers of over-the-counter drugs to fund the F.D.A. review process or to fund studies into drugs that went on the market before 1962. Leaders need to suggest more options. There should also be a way to prioritize which drugs to look at first. The agency should review old drugs for which there are already many complaints about lack of effectiveness in the manner it did recently for phenylephrine.

Right now, Americans spend billions on drugs that contain ingredients that will not help them. That’s not just a waste of money — it could mean they are delaying appropriate treatment, which can lead to more severe illnesses. This is risky not only for health but also for trust. The American public deserves medicines that do what they are advertised to do.

Mermaids, the UK charity for, in their own words, ‘gender variant and transgender children’ is under the spotlight. Following investigations by the Telegraph and Mail newspapers, as well as demands from critics concerned about child safeguarding, the Charity Commission has launched a regulatory compliance case and have said that they have written to the organisation’s trustees

The investigations found that Mermaids has been offering breast binders to girls reportedly as young as 13, and despite children saying their parents opposed the practice. Binding can often cause breathing difficulties, back pain and broken ribs. It was also uncovered that kids have been ‘congratulated’ online for identifying as transgender by staff and volunteers on the charity’s online help centre, with teenagers being advised that puberty blockers are safe and ‘totally reversible’.

Mermaids has been given half a million pounds in total from the National Lottery, and lauded by the likes of Emma Watson, Jameela Jamil and even Harry and Meghan. In other words, the charity has had powerful supporters and been like Teflon for a very long time. Starbucks did a fundraiser for them, more than 40 schools invited them in to educate teachers and kids about ‘gender identity’, and a number of corporates sponsor the charity.

John Kenneth Galbraith assessed the trajectory of America’s increasingly “affluent society.” His outlook was not a happy one. The nation’s increasingly evident material prosperity was not making its citizens any more satisfied. Nor, at least in its existing form, was it likely to do so

One reason, Galbraith argued, was the glaring imbalance between the opulence in consumption of private goods and the poverty, often squalor, of public services like schools and parks

nother was that even the bountifully supplied private goods often satisfied no genuine need, or even desire; a vast advertising apparatus generated artificial demand for them, and satisfying this demand failed to provide meaningful or lasting satisfaction.

Covid virginity is becoming more special now that it describes a shrinking minority. The lucky few, like weight-loss gurus, are only too happy to share their secrets to success.

Some sound quite reasonable, such as virologist Angela Rasmussen, who tweeted that despite resuming travel to scientific conferences, she’s remained uninfected by wearing high quality masks when warranted, skipping the hotel gym, eating outdoors and walking instead of cabbing if possible.

Others are more extreme, such as the expert who Tweeted that, among other measures, he sealed his N95 tightly on his face for the entire trip from the U.S. to Australia. He never removed it even to take a sip of water.

Numerous other Osage had died suspiciously — the cause of death often cloaked behind alcoholic poisoning or wasting illness or as simply unknown. Despite evidence that the victims had been murdered for their oil money, the cases were never properly investigated. Moreover, they could not be linked to the same killer caught by the bureau. The history of the Reign of Terror was less a question of who did it than who didn’t do it.

even now, as their stories are being dramatized in a movie and shown in theaters across the country, there is a campaign in Oklahoma — this time with legislation — to deter the history from being taught in schools.

The Osage had these events seared in their memories. Yet most Americans had excised even the bureau’s sanitized account from their consciences. Like the Tulsa Race Massacre, which occurred during the same period, the Osage Reign of Terror was generally not taught in schools, even in Oklahoma

Social scientists have identified at least three major forces that collectively bind together successful democracies: social capital (extensive social networks with high levels of trust), strong institutions, and shared stories.

Social media has weakened all three.

gradually, social-media users became more comfortable sharing intimate details of their lives with strangers and corporations. As I wrote in a 2019 Atlantic article with Tobias Rose-Stockwell, they became more adept at putting on performances and managing their personal brand—activities that might impress others but that do not deepen friendships in the way that a private phone conversation will.