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grayton downing

Weird Science! Don't mount so fast! That bug could be a boy | Science News - 0 views

www.sciencenews.org/...mount-so-fast-bug-could-be-boy

science research boy

shared by grayton downing on 26 Oct 13 - No Cached
  • There are many animal species out there that exhibit same-sex mating behavior.
  • When it comes to bugs, is it intentional same-sex behavior? Or is it all a mistake?
  • They tried to tease out why same-sex sexual behavior might occur in insects. What are the benefits? The potential downsides? And from that, to hypothesize why it might occur.
  • ...5 more annotations...
  • Why does it happen? Some say that by mating with a “passive” male and transferring sperm, that sperm then gets passed over to the female when the passive male mates. Sneaky. But does it really happen?
  • If it is mistaken identity, as the authors hypothesize, it certainly happens a lot. Why could you get so many cases of false identity
  • In many observed cases, the males being mated with attempted to fight off the attackers. In others, they may emit pheromones of their own that let the males know that nope, this isn’t what you’re looking for. In some cases, the targeted male just runs away. But it’s hard to tell how often this happens, as no one has ever really studied it.
  • t very few of the hypotheses have been tested. Most of the insect orders in which male same-sex behavior has been documented have at most one or two studies. And of those, most are not focused on same-sex mating behavior; they just list it as a by-product
  • So it would be interesting to test these hypotheses, and to figure out what is really driving the guy-on-guy bug action. Is it pheromones? Desperation? Safety in numbers? Or something else? Science in the future will have to tell. 
Javier E

What Shamu Taught Me About a Happy Marriage - New York Times - 0 views

www.nytimes.com/...25love.html

training behavior reward animal technique approximation psychology learning

shared by Javier E on 28 Dec 14 - No Cached
smnasha liked it
  • like many wives before me, I ignored a library of advice books and set about improving him. By nagging, of course, which only made his behavior worse: he'd drive faster instead of slower; shave less frequently, not more; and leave his reeking bike garb on the bedroom floor longer than ever.
  • For a book I was writing about a school for exotic animal trainers, I started commuting from Maine to California, where I spent my days watching students do the seemingly impossible: teaching hyenas to pirouette on command, cougars to offer their paws for a nail clipping, and baboons to skateboard.
  • The central lesson I learned from exotic animal trainers is that I should reward behavior I like and ignore behavior I don't. After all, you don't get a sea lion to balance a ball on the end of its nose by nagging. The same goes for the American husband.
  • ...3 more annotations...
  • I was using what trainers call "approximations," rewarding the small steps toward learning a whole new behavior. You can't expect a baboon to learn to flip on command in one session, just as you can't expect an American husband to begin regularly picking up his dirty socks by praising him once for picking up a single sock.
  • With Scott the husband, I began to praise every small act every time: if he drove just a mile an hour slower, tossed one pair of shorts into the hamper, or was on time for anything.
  • Enlightened trainers learn all they can about a species, from anatomy to social structure, to understand how it thinks, what it likes and dislikes, what comes easily to it and what doesn't.
Javier E

It's Time for a Real Code of Ethics in Teaching - Noah Berlatsky - The Atlantic - 3 views

www.theatlantic.com/...274722

ethics teaching cheating analysis education

shared by Javier E on 07 Apr 13 - No Cached
  • More 5inShare Email Print A defendant in the Atlanta Public Schools case turns herself in at the Fulton County Jail on April 2. (David Goldman/AP) Earlier this week at The Atlantic, Emily Richmond asked whether high-stakes testing caused the Atlanta schools cheating scandal. The answer, I would argue, is yes... just not in the way you might think. Tests don't cause unethical behavior. But they did cause the Atlanta cheating scandal, and they are doing damage to the teaching profession. The argument that tests do not cause unethical behavior is fairly straightforward, and has been articulated by a number of writers. Jonathan Chait quite correctly points out that unethical behavior occurs in virtually all professions -- and that it occurs particularly when there are clear incentives to succeed. Incentivizing any field increases the impetus to cheat. Suppose journalism worked the way teaching traditionally had. You get hired at a newspaper, and your advancement and pay are dictated almost entirely by your years on the job, with almost no chance of either becoming a star or of getting fired for incompetence. Then imagine journalists changed that and instituted the current system, where you can get really successful if your bosses like you or be fired if they don't. You could look around and see scandal after scandal -- phone hacking! Jayson Blair! NBC's exploding truck! Janet Cooke! Stephen Glass! -- that could plausibly be attributed to this frightening new world in which journalists had an incentive to cheat in order to get ahead. It holds true of any field. If Major League Baseball instituted tenure, and maybe used tee-ball rules where you can't keep score and everybody gets a chance to hit, it could stamp out steroid use. Students have been cheating on tests forever -- massive, systematic cheating, you could say. Why? Because they have an incentive to do well. Give teachers and administrators an incentive for their students to do well, and more of them will cheat. For Chait, then, teaching has just been made more like journalism or baseball; it has gone from an incentiveless occupation to one with incentives.
  • Chait refers to violations of journalistic ethics -- like the phone-hacking scandal -- and suggests they are analogous to Major-League steroid use, and that both are similar to teachers (or students) cheating on tests. But is phone hacking "cheating"
  • Phone hacking was, then, not an example of cheating. It was a violation of professional ethics. And those ethics are not arbitrarily imposed, but are intrinsic to the practice of journalism as a profession committed to public service and to truth.
  • ...8 more annotations...
  • Behaving ethically matters, but how it matters, and what it means, depends strongly on the context in which it occurs.
  • Ethics for teachers is not, apparently, first and foremost about educating their students, or broadening their minds. Rather, ethics for teachers in our current system consists in following the rules. The implicit, linguistic signal being given is that teachers are not like journalists or doctors, committed to a profession and to the moral code needed to achieve their professional goals. Instead, they are like athletes playing games, or (as Chait says) like children taking tests.
  • Using "cheating" as an ethical lens tends to both trivialize and infantilize teacher's work
  • Professions with social respect and social capital, like doctors and lawyers, collaborate in the creation of their own standards. The assumption is that those standards are intrinsic to the profession's goals, and that, therefore, professionals themselves are best equipped to establish and monitor them. Teachers' standards, though, are imposed from outside -- as if teachers are children, or as if teaching is a game.
  • High-stakes testing, then, does leads to cheating. It does not create unethical behavior -- but it does create the particular unethical behavior of "cheating."
  • We have reached a point where we can only talk about the ethics of the profession in terms of cheating or not cheating, as if teachers' main ethical duty is to make sure that scantron bubbles get filled in correctly. Teachers, like journalists, should have a commitment to truth; like doctors, they have a duty of care. Translating those commitments and duties into a bureaucratized measure of cheating-or-not-cheating diminishes ethic
  • For teachers it is, literally, demoralizing. It severs the moral experience of teaching from the moral evaluation of teaching, which makes it almost impossible for good teachers (in all the senses of "good") to stay in the system.
  • We need better ethics for teachers -- ethics that treat them as adults and professionals, not like children playing games.
Javier E

Look At Me by Patricia Snow | Articles | First Things - 0 views

www.firstthings.com/...look-at-me

interaction personal tech conversation distraction robot parenting autism

shared by Javier E on 08 Jun 19 - No Cached
  • Maurice stumbles upon what is still the gold standard for the treatment of infantile autism: an intensive course of behavioral therapy called applied behavioral analysis that was developed by psychologist O. Ivar Lovaas at UCLA in the 1970s
  • in a little over a year’s time she recovers her daughter to the point that she is indistinguishable from her peers.
  • Let Me Hear Your Voice is not a particularly religious or pious work. It is not the story of a miracle or a faith healing
  • ...54 more annotations...
  • Maurice discloses her Catholicism, and the reader is aware that prayer undergirds the therapy, but the book is about the therapy, not the prayer. Specifically, it is about the importance of choosing methods of treatment that are supported by scientific data. Applied behavioral analysis is all about data: its daily collection and interpretation. The method is empirical, hard-headed, and results-oriented.
  • on a deeper level, the book is profoundly religious, more religious perhaps than its author intended. In this reading of the book, autism is not only a developmental disorder afflicting particular individuals, but a metaphor for the spiritual condition of fallen man.
  • Maurice’s autistic daughter is indifferent to her mother
  • In this reading of the book, the mother is God, watching a child of his wander away from him into darkness: a heartbroken but also a determined God, determined at any cost to bring the child back
  • the mother doesn’t turn back, concedes nothing to the condition that has overtaken her daughter. There is no political correctness in Maurice’s attitude to autism; no nod to “neurodiversity.” Like the God in Donne’s sonnet, “Batter my heart, three-personed God,” she storms the walls of her daughter’s condition
  • Like God, she sets her sights high, commits both herself and her child to a demanding, sometimes painful therapy (life!), and receives back in the end a fully alive, loving, talking, and laughing child
  • the reader realizes that for God, the harrowing drama of recovery is never a singular, or even a twice-told tale, but a perennial one. Every child of his, every child of Adam and Eve, wanders away from him into darkness
  • we have an epidemic of autism, or “autism spectrum disorder,” which includes classic autism (Maurice’s children’s diagnosis); atypical autism, which exhibits some but not all of the defects of autism; and Asperger’s syndrome, which is much more common in boys than in girls and is characterized by average or above average language skills but impaired social skills.
  • At the same time, all around us, we have an epidemic of something else. On the street and in the office, at the dinner table and on a remote hiking trail, in line at the deli and pushing a stroller through the park, people go about their business bent over a small glowing screen, as if praying.
  • This latter epidemic, or experiment, has been going on long enough that people are beginning to worry about its effects.
  • for a comprehensive survey of the emerging situation on the ground, the interested reader might look at Sherry Turkle’s recent book, Reclaiming Conversation: The Power of Talk in a Digital Age.
  • she also describes in exhaustive, chilling detail the mostly horrifying effects recent technology has had on families and workplaces, educational institutions, friendships and romance.
  • many of the promises of technology have not only not been realized, they have backfired. If technology promised greater connection, it has delivered greater alienation. If it promised greater cohesion, it has led to greater fragmentation, both on a communal and individual level.
  • If thinking that the grass is always greener somewhere else used to be a marker of human foolishness and a temptation to be resisted, today it is simply a possibility to be checked out. The new phones, especially, turn out to be portable Pied Pipers, irresistibly pulling people away from the people in front of them and the tasks at hand.
  • all it takes is a single phone on a table, even if that phone is turned off, for the conversations in the room to fade in number, duration, and emotional depth.
  • an infinitely malleable screen isn’t an invitation to stability, but to restlessness
  • Current media, and the fear of missing out that they foster (a motivator now so common it has its own acronym, FOMO), drive lives of continual interruption and distraction, of virtual rather than real relationships, and of “little” rather than “big” talk
  • if you may be interrupted at any time, it makes sense, as a student explains to Turkle, to “keep things light.”
  • we are reaping deficits in emotional intelligence and empathy; loneliness, but also fears of unrehearsed conversations and intimacy; difficulties forming attachments but also difficulties tolerating solitude and boredom
  • consider the testimony of the faculty at a reputable middle school where Turkle is called in as a consultant
  • The teachers tell Turkle that their students don’t make eye contact or read body language, have trouble listening, and don’t seem interested in each other, all markers of autism spectrum disorder
  • Like much younger children, they engage in parallel play, usually on their phones. Like autistic savants, they can call up endless information on their phones, but have no larger context or overarching narrative in which to situate it
  • Students are so caught up in their phones, one teacher says, “they don’t know how to pay attention to class or to themselves or to another person or to look in each other’s eyes and see what is going on.
  • “It is as though they all have some signs of being on an Asperger’s spectrum. But that’s impossible. We are talking about a schoolwide problem.”
  • Can technology cause Asperger’
  • “It is not necessary to settle this debate to state the obvious. If we don’t look at our children and engage them in conversation, it is not surprising if they grow up awkward and withdrawn.”
  • In the protocols developed by Ivar Lovaas for treating autism spectrum disorder, every discrete trial in the therapy, every drill, every interaction with the child, however seemingly innocuous, is prefaced by this clear command: “Look at me!”
  • If absence of relationship is a defining feature of autism, connecting with the child is both the means and the whole goal of the therapy. Applied behavioral analysis does not concern itself with when exactly, how, or why a child becomes autistic, but tries instead to correct, do over, and even perhaps actually rewire what went wrong, by going back to the beginning
  • Eye contact—which we know is essential for brain development, emotional stability, and social fluency—is the indispensable prerequisite of the therapy, the sine qua non of everything that happens.
  • There are no shortcuts to this method; no medications or apps to speed things up; no machines that can do the work for us. This is work that only human beings can do
  • it must not only be started early and be sufficiently intensive, but it must also be carried out in large part by parents themselves. Parents must be trained and involved, so that the treatment carries over into the home and continues for most of the child’s waking hours.
  • there are foundational relationships that are templates for all other relationships, and for learning itself.
  • Maurice’s book, in other words, is not fundamentally the story of a child acquiring skills, though she acquires them perforce. It is the story of the restoration of a child’s relationship with her parents
  • it is also impossible to overstate the time and commitment that were required to bring it about, especially today, when we have so little time, and such a faltering, diminished capacity for sustained engagement with small children
  • The very qualities that such engagement requires, whether our children are sick or well, are the same qualities being bred out of us by technologies that condition us to crave stimulation and distraction, and by a culture that, through a perverse alchemy, has changed what was supposed to be the freedom to work anywhere into an obligation to work everywhere.
  • In this world of total work (the phrase is Josef Pieper’s), the work of helping another person become fully human may be work that is passing beyond our reach, as our priorities, and the technologies that enable and reinforce them, steadily unfit us for the work of raising our own young.
  • in Turkle’s book, as often as not, it is young people who are distressed because their parents are unreachable. Some of the most painful testimony in Reclaiming Conversation is the testimony of teenagers who hope to do things differently when they have children, who hope someday to learn to have a real conversation, and so o
  • it was an older generation that first fell under technology’s spell. At the middle school Turkle visits, as at many other schools across the country, it is the grown-ups who decide to give every child a computer and deliver all course content electronically, meaning that they require their students to work from the very medium that distracts them, a decision the grown-ups are unwilling to reverse, even as they lament its consequences.
  • we have approached what Turkle calls the robotic moment, when we will have made ourselves into the kind of people who are ready for what robots have to offer. When people give each other less, machines seem less inhuman.
  • robot babysitters may not seem so bad. The robots, at least, will be reliable!
  • If human conversations are endangered, what of prayer, a conversation like no other? All of the qualities that human conversation requires—patience and commitment, an ability to listen and a tolerance for aridity—prayer requires in greater measure.
  • this conversation—the Church exists to restore. Everything in the traditional Church is there to facilitate and nourish this relationship. Everything breathes, “Look at me!”
  • there is a second path to God, equally enjoined by the Church, and that is the way of charity to the neighbor, but not the neighbor in the abstract.
  • “Who is my neighbor?” a lawyer asks Jesus in the Gospel of Luke. Jesus’s answer is, the one you encounter on the way.
  • Virtue is either concrete or it is nothing. Man’s path to God, like Jesus’s path on the earth, always passes through what the Jesuit Jean Pierre de Caussade called “the sacrament of the present moment,” which we could equally call “the sacrament of the present person,” the way of the Incarnation, the way of humility, or the Way of the Cross.
  • The tradition of Zen Buddhism expresses the same idea in positive terms: Be here now.
  • Both of these privileged paths to God, equally dependent on a quality of undivided attention and real presence, are vulnerable to the distracting eye-candy of our technologies
  • Turkle is at pains to show that multitasking is a myth, that anyone trying to do more than one thing at a time is doing nothing well. We could also call what she was doing multi-relating, another temptation or illusion widespread in the digital age. Turkle’s book is full of people who are online at the same time that they are with friends, who are texting other potential partners while they are on dates, and so on.
  • This is the situation in which many people find themselves today: thinking that they are special to someone because of something that transpired, only to discover that the other person is spread so thin, the interaction was meaningless. There is a new kind of promiscuity in the world, in other words, that turns out to be as hurtful as the old kind.
  • Who can actually multitask and multi-relate? Who can love everyone without diluting or cheapening the quality of love given to each individual? Who can love everyone without fomenting insecurity and jealousy? Only God can do this.
  • When an individual needs to be healed of the effects of screens and machines, it is real presence that he needs: real people in a real world, ideally a world of God’s own making
  • Nature is restorative, but it is conversation itself, unfolding in real time, that strikes these boys with the force of revelation. More even than the physical vistas surrounding them on a wilderness hike, unrehearsed conversation opens up for them new territory, open-ended adventures. “It was like a stream,” one boy says, “very ongoing. It wouldn’t break apart.”
  • in the waters of baptism, the new man is born, restored to his true parent, and a conversation begins that over the course of his whole life reminds man of who he is, that he is loved, and that someone watches over him always.
  • Even if the Church could keep screens out of her sanctuaries, people strongly attached to them would still be people poorly positioned to take advantage of what the Church has to offer. Anxious people, unable to sit alone with their thoughts. Compulsive people, accustomed to checking their phones, on average, every five and a half minutes. As these behaviors increase in the Church, what is at stake is man’s relationship with truth itself.
kaylynfreeman

How the brain paralyzes you while you sleep -- ScienceDaily - 1 views

www.sciencedaily.com/...210114085417.htm

science research knowledge technology brain science

shared by kaylynfreeman on 17 Jan 21 - No Cached
  • In reality though, narcolepsy, cataplexy, and rapid eye movement (REM) sleep behavior disorder are all serious sleep-related illnesses. Researchers at the University of Tsukuba led by Professor Takeshi Sakurai have found neurons in the brain that link all three disorders and could provide a target for treatments.
  • In reality though, narcolepsy, cataplexy, and rapid eye movement (REM) sleep behavior disorder are all serious sleep-related illnesses. Researchers at the University of Tsukuba led by Professor Takeshi Sakurai have found neurons in the brain that link all three disorders and could provide a target for treatments.
    • margogramiak
      margogramiak on 17 Jan 21
       
      Cures or fixes to these disorders would change a lot of peoples lives.
  • Instead of being still during REM sleep, muscles move around, often going as far as to stand up and jump, yell, or punch.
    • margogramiak
      margogramiak on 17 Jan 21
       
      It makes sense that this would lead to poor sleep!
  • ...6 more annotations...
  • When the researchers blocked the input to these neurons, the mice began moving during their sleep, just like someone with REM sleep behavior disorder.
    • margogramiak
      margogramiak on 17 Jan 21
       
      It's really cool that they found a source! How is this information applicable to a cure? Where do they go now?
  • Narcolepsy is characterized by suddenly falling asleep at any time during the day, even in mid-sentence. Cataplexy is a related illness in which people suddenly lose muscle tone and collapse.
    • margogramiak
      margogramiak on 17 Jan 21
       
      Are they associated with REM?
  • They tested their hypothesis using a mouse model of narcolepsy in which cataplexic attacks could be triggered by chocolate. "We found that silencing the SLD-to-ventral medial medulla reduced the number of cataplexic bouts,"
    • margogramiak
      margogramiak on 17 Jan 21
       
      Interesting
  • The glycinergic neurons we have identified in the ventral medial medulla could be a good target for drug therapies for people with narcolepsy, cataplexy, or REM sleep behavior disorder,
    • margogramiak
      margogramiak on 17 Jan 21
       
      Cool! So there's a shot at a fix.
  • "They were connected to neurons that control voluntary movements, but not those that control muscles in the eyes or internal organs. Importantly, they were inhibitory, meaning that they can prevent muscle movement when active."
  • "The glycinergic neurons we have identified in the ventral medial medulla could be a good target for drug therapies for people with narcolepsy, cataplexy, or REM sleep behavior disorder,"
manhefnawi

Reading Aloud to Your Kids Can Promote Good Behavior and Sharpen Their Attention | Ment... - 0 views

mentalfloss.com/...or-and-sharpen-their-attention

Behavior

shared by manhefnawi on 12 Jun 18 - No Cached
  • the simple act of reading to your kids can also influence their behavior in surprising ways.
  • They found that 3-year-olds taking part in the study had a much lower chance of being aggressive or hyperactive than children in the control group of the same age.
  • the study subjects showed fewer behavioral problems and better focus than their peers who didn't receive the same intervention.
Javier E

Implicit Bias Training Isn't Improving Corporate Diversity - Bloomberg - 0 views

www.bloomberg.com/...-improving-corporate-diversity

training bias effectiveness racism diversity

shared by Javier E on 05 Aug 20 - No Cached
  • despite the growing adoption of unconscious bias training, there is no convincing scientific evidence that it works
  • In fact, much of the academic evidence on implicit bias interventions highlights their weakness as a method for boosting diversity and inclusion. Instructions to suppress stereotypes often have the opposite effect, and prejudice reduction programs are much more effective when people are already open-minded, altruistic, and concerned about their prejudices to begin with.
  • This is because the main problem with stereotypes is not that people are unaware of them, but that they agree with them (even when they don’t admit it to others). In other words, most people have conscious biases.
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  • Moreover, to the extent that people have unconscious biases, there is no clear-cut way to measure them
  • The main tool for measuring unconscious bias, the Implicit Association Test (IAT), has been in use for twenty years but is highly contested.
  • meta-analytic reviews have concluded that IAT scores — in other words, unconscious biases — are very weak predictors of actual behavior.
  • The vast majority of people labeled “racist” by these tests behave the same as the vast majority of people labelled “non-racist.” Do we really want to tell people who behave in non-racist ways that they are unconsciously racists, or, conversely, tell people who behave in racist ways that they aren’t, deep down, racists at all?
  • Instead of worrying what people think of something or someone deep down, we should focus on ways to eliminate the toxic or prejudiced behaviors we can see. That alone will drive a great deal of progress.
  • Scientific evidence suggests that the relationship between attitudes and behaviors is much weaker than one might expect.
  • Even if we lived in a world in which humans always acted in accordance with their beliefs, there would remain better ways to promote diversity than by policing people’s thoughts.
  • Organizations should focus less on extinguishing their employees’ unconscious thoughts, and more on nurturing ethical, benevolent, and inclusive behaviors.
  • This means focusing less on employees’ attitudes, and more on organizational policies and systems, as these play the key role creating the conditions that entice employees (and leaders) to behave in more or less inclusive ways.
  • This gets to the underlying flaw with unconscious bias trainings: behaviors, not thoughts, should be the target of diversity and inclusion interventions.
  • Tomas Chamorro-Premuzic is chief talent scientist at Manpower Group and a professor at University College London and Columbia University.
peterconnelly

Your Bosses Could Have a File on You, and They May Misinterpret It - The New York Times - 0 views

www.nytimes.com/...-threat-private-companies.html

new york times

shared by peterconnelly on 03 Jun 22 - No Cached
  • The company you work for may want to know. Some corporate employers fear that employees could leak information, allow access to confidential files, contact clients inappropriately or, in the extreme, bring a gun to the office.
  • at times using behavioral science tools like psychology.
  • But in spite of worries that workers might be, reasonably, put off by a feeling that technology and surveillance are invading yet another sphere of their lives, employers want to know which clock-punchers may harm their organizations.
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  • “There is so much technology out there that employers are experimenting with or investing in,” said Edgar Ndjatou
  • Software can watch for suspicious computer behavior or it can dig into an employee’s credit reports, arrest records and marital-status updates. It can check to see if Cheryl is downloading bulk cloud data or run a sentiment analysis on Tom’s emails to see if he’s getting testier over time. Analysis of this data, say the companies that monitor insider risk, can point to potential problems in the workplace.
  • Organizations that produce monitoring software and behavioral analysis for the feds also may offer conceptually similar tools to private companies, either independently or packaged with broader cybersecurity tools.
  • But corporations are moving forward with their own software-enhanced surveillance. While private-sector workers may not be subjected to the rigors of a 136-page clearance form, private companies help build these “continuous vetting” technologies for the federal government, said Lindy Kyzer of ClearanceJobs. Then, she adds, “Any solution would have private-sector applications.”
  • “Can we build a system that checks on somebody and keeps checking on them and is aware of that person’s disposition as they exist in the legal systems and the public record systems on a continuous basis?” said Chris Grijalva
  • But the interest in anticipating insider threats in the private sector raises ethical questions about what level of monitoring nongovernmental employees should be subject to.
  • “People are starting to understand that the insider threat is a business problem and should be handled accordingly,” said Mr. Grijalva.
  • The linguistic software package they developed, called SCOUT, uses psycholinguistic analysis to seek flags that, among other things, indicate feelings of disgruntlement, like victimization, anger and blame.
  • “The language changes in subtle ways that you’re not aware of,” Mr. Stroz said.
  • There’s not enough information, in other words, to construct algorithms about trustworthiness from the ground up. And that would hold in either the private or the public sector.
  • Even if all that dystopian data did exist, it would still be tricky to draw individual — rather than simply aggregate — conclusions about which behavioral indicators potentially presaged ill actions.
  • “Depending too heavily on personal factors identified using software solutions is a mistake, as we are unable to determine how much they influence future likelihood of engaging in malicious behaviors,” Dr. Cunningham said.
  • “I have focused very heavily on identifying indicators that you can actually measure, versus those that require a lot of interpretation,” Dr. Cunningham said. “Especially those indicators that require interpretation by expert psychologists or expert so-and-sos. Because I find that it’s a little bit too dangerous, and I don’t know that it’s always ethical.”
Emily Horwitz

Scientists to Seek Clues to Violence in Genome of Gunman in Newtown, Conn. - NYTimes.com - 0 views

www.nytimes.com/...of-gunman-in-newtown-conn.html

genetics newtown biology nytimes science knowledge bias

shared by Emily Horwitz on 27 Dec 12 - No Cached
  • In a move likely to renew a longstanding ethical controversy, geneticists are quietly making plans to study the DNA of Adam Lanza, 20, who killed 20 children and seven adults in Newtown, Conn. Their work will be an effort to discover biological clues to extreme violence.
  • other experts speculated that the geneticists might look for mutations that might be associated with mental illnesses and ones that might also increase the risk for violence.
  • But whatever they do, this apparently is the first time researchers will attempt a detailed study of the DNA of a mass killer.
  • ...6 more annotations...
  • Dr. Arthur Beaudet, a professor at the Baylor College of Medicine and the chairman of its department of molecular and human genetics, applaud the effort. He believes that the acts committed by men like Mr. Lanza and the gunmen in other rampages in recent years — at Columbine High School and in Aurora, Colo., in Norway, in Tucson and at Virginia Tech — are so far off the charts of normal behavior that there must be genetic changes driving them.
  • Everything known about mental illness, these skeptics say, argues that there are likely to be hundreds of genes involved in extreme violent behavior, not to mention a variety of environmental influences, and that all of these factors can interact in complex and unpredictable ways.
  • The National Institutes of Health was embroiled in controversy about 20 years ago simply for proposing to study the biological underpinnings of violence. Critics accused researchers of racism and singling out minorities, especially black men.
  • Studies of people at the far end of a bell curve can be especially informative, because the genetic roots of their conditions can be stark and easy to spot, noted J. H. Pate Skene, a Duke University neurobiologist. “I think doing research on outliers, people at an end of a spectrum on something of concern like violent behavior, is certainly a good idea,” he said, but he advised tempering expectations.
  • “If we know someone has a 2 percent chance or a 10 percent chance or a 20 percent chance of violent behavior, what would you do with that person?” Dr. Skene said. “They have not been convicted of anything — have not done anything wrong.”
  • Ultimately, understanding the genetics of violence might enable researchers to find ways to intervene before a person commits a horrific crime. But that goal would be difficult to achieve, and the pursuit of it risks jeopardizing personal liberties.
sissij

Emotions | Being Human - 2 views

www.beinghuman.org/emotions

emotions human science research psychology

shared by sissij on 26 Nov 16 - No Cached
  • They come and go, changing like the weather in April: sunny, rainy, stormy, mild or thunderous. Usually we find a reason why we’re happy or sad, embarrassed, or proud.
  • Although most people feel that emotions are one of the most personal, intimate, private expressions, an evolutionary understanding implies that they are, instead, impersonal mechanisms that we all share.
  • The basic emotions—fear, sorrow, disgust, anger, and joy—evolved as mechanisms to instigate behaviors appropriate to the environments of our distant ancestors.
  • ...2 more annotations...
  • Guilt signals that we’ve violated morals we believe in; embarrassment shows that we’ve made a fool out of ourselves
  • We evolved lo earn from emotions and they shape our behavior continually. Fundamentally we try to avoid unpleasant emotions and experience pleasant ones because they indicate situations that are either beneficial or harmful for us.
  • sissij on 26 Nov 16
     
    I found this article very interesting because it shows me another aspect of emotion, as a very impersonal shared knowledge that's developed by the logic of evolution. I think there are some similarities between emotions and languages as they both shape our behavior continually, and also emotion can be used a tool of communication in a way just like language. Actually, I think emotions serve as the very primitive form of communication in the early phase of human. --Sissi (11/26/2016)
Javier E

Coping with Chaos in the White House - Medium - 0 views

medium.com/...n-the-white-house-697fa2ca3ddf

Trump narcissism character psychology

shared by Javier E on 03 Dec 16 - No Cached
  • I am not a professional and this is not a diagnosis. My post is not intended to persuade anyone or provide a comprehensive description of NPD. I am speaking purely from decades of dealing with NPD and sharing strategies that were helpful for me in coping and predicting behavior.
  • Here are a few things to keep in mind:
  • 1) It’s not curable and it’s barely treatable. He is who he is. There is no getting better, or learning, or adapting. He’s not going to “rise to the occasion” for more than maybe a couple hours. So just put that out of your mind.
  • ...11 more annotations...
  • 2) He will say whatever feels most comfortable or good to him at any given time. He will lie a lot, and say totally different things to different people. Stop being surprised by this. While it’s important to pretend “good faith” and remind him of promises, as Bernie Sanders and others are doing, that’s for his supporters, so *they* can see the inconsistency as it comes. He won’t care. So if you’re trying to reconcile or analyze his words, don’t. It’s 100% not worth your time. Only pay attention to and address his actions.
  • 3) You can influence him by making him feel good. There are already people like Bannon who appear ready to use him for their own ends. The GOP is excited to try. Watch them, not him.
  • 4) Entitlement is a key aspect of the disorder. As we are already seeing, he will likely not observe traditional boundaries of the office. He has already stated that rules don’t apply to him. This particular attribute has huge implications for the presidency and it will be important for everyone who can to hold him to the same standards as previous presidents.
  • 5) We should expect that he only cares about himself and those he views as extensions of himself, like his children. (People with NPD often can’t understand others as fully human or distinct.) He desires accumulation of wealth and power because it fills a hole.
  • He will have no qualms *at all* about stealing everything he can from the country, and he’ll be happy to help others do so, if they make him feel good. He won’t view it as stealing but rather as something he’s entitled to do. This is likely the only thing he will intentionally accomplish.
  • 6) It’s very, very confusing for non-disordered people to experience a disordered person with NPD. While often intelligent, charismatic and charming, they do not reliably observe social conventions or demonstrate basic human empathy. It’s very common for non-disordered people to lower their own expectations and try to normalize the behavior. DO NOT DO THIS
  • 7) People with NPD often recruit helpers, referred to in the literature as “enablers” when they allow or cover for bad behavior and “flying monkeys” when they perpetrate bad behavior
  • 8) People with NPD often foster competition for sport in people they control. Expect lots of chaos, firings and recriminations. He will probably behave worst toward those closest to him, but that doesn’t mean (obviously) that his actions won’t have consequences for the rest of us. He will punish enemies.
  • 9) Gaslighting — where someone tries to convince you that the reality you’ve experienced isn’t true — is real and torturous. He will gaslight, his followers will gaslight.
  • Learn the signs and find ways to stay focused on what you know to be true. Note: it is typically not helpful to argue with people who are attempting to gaslight. You will only confuse yourself. Just walk away.
  • 10) Whenever possible, do not focus on the narcissist or give him attention. Unfortunately we can’t and shouldn’t ignore the president, but don’t circulate his tweets or laugh at him — you are enabling him and getting his word out.
Javier E

A Harvard Scholar on the Enduring Lessons of Chinese Philosophy - The New York Times - 0 views

www.nytimes.com/...-philosophy-harvard-puett.html

psychology philosophy self good liberation self-help

shared by Javier E on 10 Aug 16 - No Cached
  • Since 2006, Michael Puett has taught an undergraduate survey course at Harvard University on Chinese philosophy, examining how classic Chinese texts are relevant today. The course is now one of Harvard’s most popular, third only to “Introduction to Computer Science” and “Principles of Economics.”
  • So-called Confucianism, for example, is read as simply being about forcing people to accept their social roles, while so-called Taoism is about harmonizing with the larger natural world. So Confucianism is often presented as bad and Taoism as good. But in neither case are we really learning from them.
  • we shouldn’t domesticate them to our own way of thinking. When we read them as self-help, we are assuming our own definition of the self and then simply picking up pieces of these ideas that fit into such a vision
  • ...11 more annotations...
  • these ideas are not about looking within and finding oneself. They are about overcoming the self. They are, in a sense, anti-self-help.
  • Today, we are often told that our goal should be to look within and find ourselves, and, once we do, to strive to be sincere and authentic to that true self, always loving ourselves and embracing ourselves for who we are. All of this sounds great and is a key part of what we think of as a properly “modern” way to live.
  • But what if we’re, on the contrary, messy selves that tend to fall into ruts and patterns of behavior? If so, the last thing we would want to be doing is embracing ourselves for who we are — embracing, in other words, a set of patterns we’ve fallen into. The goal should rather be to break these patterns and ruts, to train ourselves to interact better with those around us.
  • Certainly some strains of Chinese political theory will take this vision of the self — that we tend to fall into patterns of behavior — to argue for a more paternalistic state that will, to use a more recent term, “nudge” us into better patterns.
  • many of the texts we discuss in the book go the other way, and argue that the goal should be to break us from being such passive creatures — calling on us to do things that break us out of these patterns and allow us to train ourselves to start altering our behavior for the better.
  • You argue that Chinese philosophy views rituals as tools that can liberate us from these ruts.
  • Rituals force us for a brief moment to become a different person and to interact with those around us in a different way. They work because they break us from the patterns that we fall into and that otherwise dominate our behavior.
  • In the early Han dynasty, for example, we have examples of rituals that called for role reversals. The father would be called upon to play the son, and the son would play the father. Each is forced to see the world from the other’s perspective, with the son learning what it’s like to be in a position of authority and the father remembering what it was like to be the more subservient one
  • We tend to think that we live in a globalized world, but in a lot of ways we really don’t. The truth is that for a long time only a very limited number of ideas have dominated the world, while ideas that arose elsewhere were seen as “traditional” and not worth learning from.
  • imagine future generations that grow up reading Du Fu along with Shakespeare, and Confucius along with Plato. Imagine that type of world, where great ideas — wherever they arose — are thought about and wrestled with.
  • There’s a very strong debate going on in China about values — a sense that everything has become about wealth and power, and a questioning about whether this should be rethought. And among the ideas that are being brought into the debate are these earlier notions about the self and about how one can lead a good life. So, while the government is appropriating some of these ideas in particular ways, the broader public is debating them, and certainly with very different interpretations.
Ellie McGinnis

The Mammoth Cometh - NYTimes.com - 2 views

www.nytimes.com/...the-mammoth-cometh.html

research science technology ethics conservation

shared by Ellie McGinnis on 27 Feb 14 - No Cached
  • Brand helped to establish in 1996 to support projects designed to inspire “long-term responsibility.”
  • The theme of the talk was “Is Mass Extinction of Life on Earth Inevitable?”
  • the resurrection of extinct species, like the woolly mammoth, aided by new genomic technologies developed by the Harvard molecular biologist George Church.
  • ...37 more annotations...
  • Just as the loss of a species decreases the richness of an ecosystem, the addition of new animals could achieve the opposite effect.
  • National Geographic Society hosted a larger conference to debate the scientific and ethical questions raised by the prospect of “de-extinction.
  • “De-extinction went from concept to potential reality right before our eyes,
  • “This may be the biggest attraction and possibly the biggest benefit of de-extinction. It would surely be very cool to see a living woolly mammoth.”
  • less scientific, if more persuasive, argument was advanced by the ethicist Hank Greely and the law professor Jacob Sherkow, both of Stanford. De-extinction should be pursued, they argued in a paper published in Science, because it would be really
  • They will replace chunks of band-tailed-pigeon DNA with synthesized chunks of passenger-pigeon DNA, until the cell’s genome matches their working passenger-pigeon genome.
  • Scientists predict that changes made by human beings to the composition of the atmosphere could kill off a quarter of the planet’s mammal species, a fifth of its reptiles and a sixth of its birds by 2050
  • This cloning method, called somatic cell nuclear transfer, can be used only on species for which we have cellular material.
  • There is a shortcut. The genome of a closely related species will have a high proportion of identical DNA, so it can serve as a blueprint, or “scaffold.”
  • By comparing the fragments of passenger-pigeon DNA with the genomes of similar species, researchers can assemble an approximation of an actual passenger-pigeon genome.
  • “We’ve framed it in terms of conservation,”
  • the genome will have to be inscribed into a living cell.
  • As with any translation, there may be errors of grammar, clumsy phrases and perhaps a few missing passages, but the book will be legible. It should, at least, tell a good story.
  • MAGE (Multiplex Automated Genome Engineering). MAGE is nicknamed the “evolution machine” because it can introduce the equivalent of millions of years of genetic mutations within minutes
  • Developmental and behavioral biologists would take over, just in time to answer some difficult questions. Chicks imitate their parents’ behavior. How do you raise a passenger pigeon without parents of its own species? And how do you train band-tailed pigeons to nurture the strange spawn that emerge from their eggs; chicks that, to them, might seem monstrous: an avian Rosemary’s Baby?
  • For endangered species with tiny populations, scientists would introduce genetic diversity to offset inbreeding.
  • They will try to alter the birds’ diets, migration habits and environment. The behavior of each subsequent generation will more closely resemble that of their genetic cousins.
  • “There’s always this fear that somehow, if we do it, we’re going to accidentally make something horrible, because only nature can really do it right. But nature is totally random. Nature makes monsters. Nature makes threats. Many of the things that are most threatening to us are a product of nature. Revive & Restore is not going to tip the balance in any way.”
  • For species threatened by contagion, an effort would be made to fortify their DNA with genes that make them disease-resistant
  • This optimistic, soft-focus fantasy of de-extinction, while thrilling to Ben Novak, is disturbing to many conservation biologists, who consider it a threat to their entire discipline and even to the environmental movement.
  • The first question posed by conservationists addresses the logic of bringing back an animal whose native habitat has disappeared. Why go through all the trouble just to have the animal go extinct all over again?
  • There is also anxiety about disease
  • “If you recreate a species genetically and release it, and that genotype is based on a bird from a 100-year-old environment, you probably will increase risk.”
  • The scientific term for this type of genetic intervention is “facilitated adaptation.”
  • De-extinction also poses a rhetorical threat to conservation biologists. The specter of extinction has been the conservation movement’s most powerful argument. What if extinction begins to be seen as a temporary inconvenience?
  • De-extinction suggests that we can technofix our way out of environmental issues generally, and that’s very, very bad.
  • How will we decide which species to resurrect?
  • Philip Seddon recently published a 10-point checklist to determine the suitability of any species for revival, taking into account causes of its extinction, possible threats it might face upon resurrection and man’s ability to destroy the species “in the event of unacceptable ecological or socioeconomic impacts.”
  • But the most visceral argument against de-extinction is animal cruelty.
  • “Is it fair to do this to these animals?” Shapiro asked. “Is ‘because we feel guilty’ a good-enough reason?” Stewart Brand made a utilitarian counterargument: “We’re going to go through some suffering, because you try a lot of times, and you get ones that don’t take. On the other hand, if you can bring bucardos back, then how many would get to live that would not have gotten to live?”
  • In “How to Permit Your Mammoth,” published in The Stanford Environmental Law Journal, Norman F. Carlin asks whether revived species should be protected by the Endangered Species Act or regulated as a genetically modified organism.
  • He concludes that revived species, “as products of human ingenuity,” should be eligible for patenting.
  • The term “de-extinction” is misleading. Passenger pigeons will not rise from the grave
  • Our understanding of the passenger pigeon’s behavior derives entirely from historical accounts.
  • There is no authoritative definition of “species.” The most widely accepted definition describes a group of organisms that can procreate with one another and produce fertile offspring, but there are many exceptions.
  • Theseus’ ship, therefore, “became a standing example among the philosophers . . . one side holding that the ship remained the same, and the other contending that it was not the same.”
  • What is coming will go well beyond the resurrection of extinct species. For millenniums, we have customized our environment, our vegetables and our animals, through breeding, fertilization and pollination. Synthetic biology offers far more sophisticated tools. The creation of novel organisms, like new animals, plants and bacteria, will transform human medicine, agriculture, energy production and much else.
Javier E

Why It's OK to Let Apps Make You a Better Person - Evan Selinger - Technology - The Atl... - 0 views

www.theatlantic.com/...254246

self person morality will agent willpower technology enhanced psychology

shared by Javier E on 19 Mar 12 - No Cached
  • one theme emerges from the media coverage of people's relationships with our current set of technologies: Consumers want digital willpower. App designers in touch with the latest trends in behavioral modification--nudging, the quantified self, and gamification--and good old-fashioned financial incentive manipulation, are tackling weakness of will. They're harnessing the power of payouts, cognitive biases, social networking, and biofeedback. The quantified self becomes the programmable self.
  • the trend still has multiple interesting dimensions
  • Individuals are turning ever more aspects of their lives into managerial problems that require technological solutions. We have access to an ever-increasing array of free and inexpensive technologies that harness incredible computational power that effectively allows us to self-police behavior everywhere we go. As pervasiveness expands, so does trust.
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  • Some embrace networked, data-driven lives and are comfortable volunteering embarrassing, real time information about what we're doing, whom we're doing it with, and how we feel about our monitored activities.
  • Put it all together and we can see that our conception of what it means to be human has become "design space." We're now Humanity 2.0, primed for optimization through commercial upgrades. And today's apps are more harbinger than endpoint.
  • philosophers have had much to say about the enticing and seemingly inevitable dispersion of technological mental prosthetic that promise to substitute or enhance some of our motivational powers.
  • beyond the practical issues lie a constellation of central ethical concerns.
  • they should cause us to pause as we think about a possible future that significantly increases the scale and effectiveness of willpower-enhancing apps. Let's call this hypothetical future Digital Willpower World and characterize the ethical traps we're about to discuss as potential general pitfalls
  • it is antithetical to the ideal of " resolute choice." Some may find the norm overly perfectionist, Spartan, or puritanical. However, it is not uncommon for folks to defend the idea that mature adults should strive to develop internal willpower strong enough to avoid external temptations, whatever they are, and wherever they are encountered.
  • In part, resolute choosing is prized out of concern for consistency, as some worry that lapse of willpower in any context indicates a generally weak character.
  • Fragmented selves behave one way while under the influence of digital willpower, but another when making decisions without such assistance. In these instances, inconsistent preferences are exhibited and we risk underestimating the extent of our technological dependency.
  • It simply means that when it comes to digital willpower, we should be on our guard to avoid confusing situational with integrated behaviors.
  • the problem of inauthenticity, a staple of the neuroethics debates, might arise. People might start asking themselves: Has the problem of fragmentation gone away only because devices are choreographing our behavior so powerfully that we are no longer in touch with our so-called real selves -- the selves who used to exist before Digital Willpower World was formed?
  • Infantalized subjects are morally lazy, quick to have others take responsibility for their welfare. They do not view the capacity to assume personal responsibility for selecting means and ends as a fundamental life goal that validates the effort required to remain committed to the ongoing project of maintaining willpower and self-control.
  • Michael Sandel's Atlantic essay, "The Case Against Perfection." He notes that technological enhancement can diminish people's sense of achievement when their accomplishments become attributable to human-technology systems and not an individual's use of human agency.
  • Borgmann worries that this environment, which habituates us to be on auto-pilot and delegate deliberation, threatens to harm the powers of reason, the most central component of willpower (according to the rationalist tradition).
  • In several books, including Technology and the Character of Contemporary Life, he expresses concern about technologies that seem to enhance willpower but only do so through distraction. Borgmann's paradigmatic example of the non-distracted, focally centered person is a serious runner. This person finds the practice of running maximally fulfilling, replete with the rewarding "flow" that can only comes when mind/body and means/ends are unified, while skill gets pushed to the limit.
  • Perhaps the very conception of a resolute self was flawed. What if, as psychologist Roy Baumeister suggests, willpower is more "staple of folk psychology" than real way of thinking about our brain processes?
  • novel approaches suggest the will is a flexible mesh of different capacities and cognitive mechanisms that can expand and contract, depending on the agent's particular setting and needs. Contrary to the traditional view that identifies the unified and cognitively transparent self as the source of willed actions, the new picture embraces a rather diffused, extended, and opaque self who is often guided by irrational trains of thought. What actually keeps the self and its will together are the given boundaries offered by biology, a coherent self narrative created by shared memories and experiences, and society. If this view of the will as an expa
  • nding and contracting system with porous and dynamic boundaries is correct, then it might seem that the new motivating technologies and devices can only increase our reach and further empower our willing selves.
  • "It's a mistake to think of the will as some interior faculty that belongs to an individual--the thing that pushes the motor control processes that cause my action," Gallagher says. "Rather, the will is both embodied and embedded: social and physical environment enhance or impoverish our ability to decide and carry out our intentions; often our intentions themselves are shaped by social and physical aspects of the environment."
  • It makes perfect sense to think of the will as something that can be supported or assisted by technology. Technologies, like environments and institutions can facilitate action or block it. Imagine I have the inclination to go to a concert. If I can get my ticket by pressing some buttons on my iPhone, I find myself going to the concert. If I have to fill out an application form and carry it to a location several miles away and wait in line to pick up my ticket, then forget it.
  • Perhaps the best way forward is to put a digital spin on the Socratic dictum of knowing myself and submit to the new freedom: the freedom of consuming digital willpower to guide me past the sirens.
charlottedonoho

Researchers Link Feelings Of Disgust And Ethical Behavior : NPR - 0 views

www.npr.org/...f-disgust-and-ethical-behavior

ethics emotion behavior

shared by charlottedonoho on 02 Jun 15 - No Cached
  • Next, we examine what happens when you feel disgusted. Maybe you've come across rotting food or a bathroom that's dirty. Well, there's new research exploring how that kind of experience affects the ethical choices you might make afterward.
  • Disgust seems to make people behave in more unethical ways, Steve. This is research by Karen Winterich, Vikas Mittal and Andrea Morales. They conducted a series of experiments. In one of them, they had volunteers view a scene from the movie "Trainspotting," and the movie showed a disgustingly dirty toilet. Other volunteers watched a documentary about a coral reef. The researchers find that volunteers who watched the disgusting scene are more likely to cheat a partner in a game they play right afterwards.
  • And they're arguing that the feeling of disgust triggers feelings of self-preservation - wanting to protect yourself from the thing that's disgusting. And the researchers are speculating that these feelings of self-preservation translate more generally into feelings of selfishness, of looking out for yourself and this produces a willingness to cheat.
  • ...1 more annotation...
  • But it's another example of this mountain of studies that suggest that the social context in the social world changes our behavior even when we're not aware of it.
Sonia Kumar

Jon Ronson Ted Talk - The Psychopath Test - 0 views

www.ted.com/...rs_to_the_psychopath_test.html

science knowledge psychology perception safety ethics

shared by Sonia Kumar on 23 Oct 13 - No Cached
  • Sonia Kumar on 23 Oct 13
     
    Jon Ronson talks about a man who pretended to be a mentally ill to avoid a prison sentence. However,the doctors and lawyers claimed that pretending to be mentally ill is psychopathic behavior. Everything the man tried to do to make himself seem normal, the doctors claimed was behavior that a manipulative psychopath may exhibit to make others "think" he is normal. It raises the question How do we really know the motives behind one's actions? How can we identify someone as psychopathic if we all exhibit a bit of psychopathic behavior? Is it ethical to hold someone in a mental hospital who exhibits psychopathic behavior but has only committed a minor felony?
grayton downing

The Neurobiology of Individuality | The Scientist Magazine® - 0 views

www.the-scientist.com/?articles.view/articleNo/35514/title/The-Neurobiology-of-Individuality/

individuality scientist research knowledge

shared by grayton downing on 24 Oct 13 - No Cached
  • a group of genetically identical mice lived in the same complex enclosure for 3 months, individuals that explored the environment more broadly grew more new neurons than less adventurous mice, according to a study
  • s a clear and quantitative demonstration that individual differences in behavior can be reflected in individual differences in brain plasticity
  • often tried to tackle the question of how individual differences in behavior and personality develop in terms of the interactions between genes and environment. “But there is next to nothing [known] about the neurobiological mechanisms underlying individuality
  • ...4 more annotations...
  • phenomenon is to look at brain plasticity, or how the brain’s structure and function change over time. Plasticity is hard to study, however, because it mostly takes place at the synaptic level
  • found that individual differences in exploratory behavior correlated with individual differences in the numbers of new neurons generated. “To out knowledge, it’s the first example of a direct link between individual behavior and individual brain plasticity,” Kempermann said.
  • could help explain why human identical twins raised in the same family end up with different personalities. “These kinds of processes are notoriously difficult to study in people, because we can’t control human environments experimentally,” said Eric Turkheimer, a psychologist at the University of Virginia, who studies how differences in the personalities of identical twins emerge over time. “That’s why an animal model is so important.”
  • with an animal model to help address the ways living our lives make us who we are,” said Kempermann. “So we have touched on an approach that allows us start to get the small part of an answer to a very big question.”
grayton downing

Optogenetics and OCD | The Scientist Magazine® - 0 views

www.the-scientist.com/?articles.view/articleNo/35887/title/Optogenetics-and-OCD/

ocd scientist research

shared by grayton downing on 23 Oct 13 - No Cached
  • abnormal brain activity seen in patients with obsessive-compulsive disorder (OCD) is a likely cause of the condition, according to two papers published today (June 6) in Science. Both studies used optogenetic techniques, which allow specific brain cells to be turned on and off at the flick of a light switch, to link the abnormal brain activity to OCD behavior in mice.
  • relationship between [neural] circuit abnormalities and [OCD-like] behavior,
  • “so I’m very aware of how severe the illness is and how important it is for us to develop new and more effective treatments.” The problem is, she added, “we don’t have a very good understanding of the pathologic changes that lead to OCD.”
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  • Ahmari turned to mice and to optogenetics—whereby specific types of brain cells can be switched on and off in response to light. The cells of interest were engineered to express light-responsive ion channels, such that when the cells are exposed to light—by means of a fiber optic cable pointing a laser at the relevant brain region—the channels open, ions flood in, and nerve impulses fire.
  • But crucially, the teams had very slightly different targets in the striatum—the general ventral striatum in the case of Ahmari’s study and the specific fast-spiking inhibitory interneurons of the centromedial striatum in Graybiel’s study, suggesting that different neural circuits send inhibitory and stimulatory signals for certain OCD-like behaviors.
  • “they’ve been able to really delineate a pathway for compulsive behaviors in a more refined way than we’ve ever been able to do in humans, and that’s exciting because it points us in the direction of pathogenesis and pathophysiology of the disorder, but also . . . to new targets for potential intervention.”
Javier E

Face It, Your Brain Is a Computer - The New York Times - 0 views

www.nytimes.com/...-your-brain-is-a-computer.html

brain computer psychology brain science

shared by Javier E on 28 Jun 15 - No Cached
  • all the standard arguments about why the brain might not be a computer are pretty weak.
  • Take the argument that “brains are parallel, but computers are serial.” Critics are right to note that virtually every time a human does anything, many different parts of the brain are engaged; that’s parallel, not serial.
  • the trend over time in the hardware business has been to make computers more and more parallel, using new approaches like multicore processors and graphics processing units.
  • ...6 more annotations...
  • The real payoff in subscribing to the idea of a brain as a computer would come from using that idea to profitably guide research. In an article last fall in the journal Science, two of my colleagues (Adam Marblestone of M.I.T. and Thomas Dean of Google) and I endeavored to do just that, suggesting that a particular kind of computer, known as the field programmable gate array, might offer a preliminary starting point for thinking about how the brain works.
  • FIELD programmable gate arrays consist of a large number of “logic block” programs that can be configured, and reconfigured, individually, to do a wide range of tasks. One logic block might do arithmetic, another signal processing, and yet another look things up in a table. The computation of the whole is a function of how the individual parts are configured. Much of the logic can be executed in parallel, much like what happens in a brain.
  • our suggestion is that the brain might similarly consist of highly orchestrated sets of fundamental building blocks, such as “computational primitives” for constructing sequences, retrieving information from memory, and routing information between different locations in the brain. Identifying those building blocks, we believe, could be the Rosetta stone that unlocks the brain.
  • it is unlikely that we will ever be able to directly connect the language of neurons and synapses to the diversity of human behavior, as many neuroscientists seem to hope. The chasm between brains and behavior is just too vast.
  • Our best shot may come instead from dividing and conquering. Fundamentally, that may involve two steps: finding some way to connect the scientific language of neurons and the scientific language of computational primitives (which would be comparable in computer science to connecting the physics of electrons and the workings of microprocessors); and finding some way to connect the scientific language of computational primitives and that of human behavior (which would be comparable to understanding how computer programs are built out of more basic microprocessor instructions).
  • If neurons are akin to computer hardware, and behaviors are akin to the actions that a computer performs, computation is likely to be the glue that binds the two.
Emilio Ergueta

Addicts, Mythmakers and Philosophers | Issue 90 | Philosophy Now - 0 views

philosophynow.org/...ts_Mythmakers_and_Philosophers

Socrates Aristotle philosophy

shared by Emilio Ergueta on 05 Jun 15 - No Cached
  • Alan Brody explains Plato’s/Socrates’ understanding of habitually bad behavior.
  • the condition is capable of creating urges and motivations which bring about highly significant losses to a person’s well-being in spite of the person’s standing preference not to live like that.
  • It’s common to change one’s mind when faced with temptation. Sometimes the choice to go ahead with the temptation is the result of a cost-benefit evaluation – in other words, it seems worthwhile to do it. At other times a person might gratify their desire or urge without entertaining any qualms or even thoughts about it. So although an addict’s habitual behavior might be atypical, rather than seeing it as a result of a compulsion they’re not strong enough to fight against, why not see their addictive behavior as something done in a willing manner, because the person feels like doing it, and/or they regard it as worth doing?
  • ...3 more annotations...
  • The experience of going along with temptation is not, Socrates argues, one in which the person protests or fights against its unreasonableness while being dragged along into gratifying it. For Socrates, ‘yielding to temptation’ is not being unwillingly overpowered, but is the experience of being a willing participant choosing what is at that moment wrongly thought to be best. This is also the essence of the willingness model of addictive behavior.
  • Aristotle thought that by asserting that when we gratify our desires for what tempts we are still doing what we think best, Socrates was denying the existence of akrasia – ‘weakness of will’, or a failure of self-restraint.
  • what the addict does can be explained in terms of Socrates’ willingness model and an addict’s immoral character: ie, they want to do it, and care more about satisfying their addiction than the consequences of doing so. The addict’s moral deficits reside in their motivations
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