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Javier E

Synthetic Thinking | Jerome Groopman | The New York Review of Books - 0 views

  • Did you hope to combine chemistry and political philosophy in some way in your medical career?
  • Chemistry requires synthetic thinking. You have to bring disparate pieces of knowledge together in order to look for a chemical structure. Political philosophy, to some degree, also involves disparate aspects of knowledge: economics, sociology, history, pure philosophy
  • I found that in medicine, you don’t have an answer when you start out. You’re looking for clues that are often distributed in different places: family history, as there might be a genetic predisposition; social history, because the person smoked or was exposed to a toxin; the physical examination, where you find that an organ might be disordered. Add to that the blood test, the CAT scan, all of it, but most importantly, the person, the psychology of the person you’re dealing with. It’s the same kind of synthetic process as political philosophy, but in a different dimension.
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  • Writing, especially the kind of writing that I do, brings together narrative, science, sometimes history, and an appreciation for the person who might be at the center of the narrative.
  • The greatest influence on me was Oliver Sacks, because he could capture people as people, and he always integrated serious science into his pieces.
  • The two subjects that were most prominent for him, as I once wrote for you, were identity and adaptation: Who is this person, despite their illness? How does that illness interface with their behavior and their decisions, how do people perceive them from the outside, and how do they try to find meaning and adapt to what looks like a disability, but sometimes—not always, but sometimes—gives them hidden strength?
  • I’ve gone from witnessing the depths of disability and death, like with AIDS: I saw some of the first people with AIDS in California, in 1982 or so. The average lifespan was six months. They were mostly young gay men, and it was devastating, the infections they got, the cancers they got. Now, with all the new drugs that have been developed, someone who gets HIV is projected to have a normal lifespan. From six months to fifty years: it’s miraculous
  • that’s part of what keeps you going: the belief that things can advance in a meaningful way.
  • Are there any major or interesting medical stories that the public doesn’t know enough about? 
  • The idea of genetic treatments. Often when people hear the words “genetics” or “DNA” or “RNA,” they shut down. The challenge is how to make it accessible.
  • There’s a wonderful line in the Talmud that says, “Whoever saves a single life saves the whole world.” There might be only a few hundred people in the whole country who have a particular genetic disorder. I
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