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Lawrence Hrubes

Dr. Bunsen / Coffee Experiments - 0 views

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    "A few years ago, I started using house guests as subjects in an experiment.1 My experiment was designed to test what variables in the coffee brewing process produce a perceptible improvement in coffee flavor. A frequent assertion is that numerous variables must be carefully considered to brew a good cup of coffee. I wanted to know if this premise was true as humans are really good at creating their own reality distortion fields. "
markfrankel18

3quarksdaily: Is Wine Tasting Nonsense? - 1 views

  • If there is such a thing as real expertise in identifying the properties of a wine, then it must be possible to get it wrong.  If tastes, in general, were entirely subjective there would be no right answer to the question of whether, for instance, chocolate ice cream tastes of chocolate.  No one really thinks that. The fact that expert wine tasters get it wrong so often is evidence that wine tasting is harder than identifying the presence of chocolate in ice cream—not that it is utterly capricious. So tastes are not so entirely subjective that our experiences of them have no relationship to an object.
  • Furthermore, tasters can strive to eliminate environmental factors that have been shown to influence judgments about wine such as conversations, the style of music being played, and changes in the weather, etc. These are all factors that wine tasters can control by adjusting the environment in which they taste. Wine tasters, if they are to maintain credibility, must taste under the appropriate conditions. But that is no different from any other normative judgment we make. Our ability to make ethical judgments, for instance, is similarly influenced by environmental factors. We know (or should know) better than to make ethical judgments when we are excessively angry, fearful, under the influence of powerful desires, etc. Yet, it does not follow from the fact that ethical judgments can be influenced by irrelevant factors that all ethical judgments are subjective.
  • So the taste of wine (or anything else) is partly dependent on objective features of the world and partly dependent on how our view of those features has been shaped by past experience. The crucial question then is how much of a distorting lens is that past experience.
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  • What is puzzling about this whole debate about the objectivity of wine critics, however, is why people want objective descriptions of wine. We don't expect scientific objectivity from art critics, literary critics, or film reviewers. The disagreements among experts in these fields are as deep as the disagreements about wine. There is no reason to think a film critic would have the same judgment about a film if viewed in a different context, in comparison with a different set of films, or after conversing about the film with other experts. Our judgments are fluid and they should be if we are to make sense of our experience. When listening to music aren't we differently affected by a song depending upon whether we are at home, in a bar, going to the beach, listening with friends or alone? Why would wine be different? The judgment of any critic is simply a snapshot at a particular time and place of an object whose meaning can vary with context. Wine criticism cannot escape this limitation.
  • What we want from critics whether of music, art, or wine is a judgment made in light of their vast experience that can show us something about the object that we might have missed without their commentary. That can be accomplished independently of whether the critic is perfectly consistent or objective. We want the critic to have a certain kind of bias, born of her unique experience, because it is that bias that enables her to taste, see, or hear what she does.
markfrankel18

What We Really Taste When We Drink Wine : The New Yorker - 2 views

  • Salzman first became interested in wine when he was a graduate student at Stanford University studying neuroscience (Ph.D.) and psychiatry (M.D.). “I was corrupted by some people who were very serious about wine,” he told me. Together, they would host wine tastings and travel to vineyards. Over time, as his interest in wine grew, he began to think about the connections between his tastings and the work he was doing on the ways in which emotion colors the way our brains process information. “We study how cognitive and emotional processes can affect perception,” he said. “And in the case of something like wine, you have the perfect example: even before you open a bottle to experience the wine itself, you already have an arbitrary visual stimulus—the bottle and the label—that comes with non-arbitrary emotional associations, good and bad.” And those emotional associations will, in turn, affect what we taste.
  • In one recent study, the Caltech neuroscientist Hilke Plassman found that people’s expectations of a wine’s price affected their enjoyment on a neural level: not only did they report greater subjective enjoyment but they showed increased activity in an area of the brain that has frequently been associated with the experience of pleasantness. The same goes for the color and shape of a wine’s label: some labels make us think that a wine is more valuable (and, hence, more tasty), while others don’t. Even your ability to pronounce a winery’s name can influence your appreciation of its product—the more difficult the name is to pronounce, the more you’ll like the wine.
  • For experts, though, the story is different. In 1990, Gregg Solomon, a Harvard psychologist who wrote “Great Expectorations: The Psychology of Expert Wine Talk,” found that amateurs can’t really distinguish different wines at all, but he also found that experts can indeed rank wines for sweetness, balance, and tannin at rates that far exceeded chance. Part of the reason isn’t just in the added experience. It’s in the ability to phrase and label that experience more precisely, a more developed sensory vocabulary that helps you to identify and remember what you experience. Indeed, when novices are trained, their discrimination ability improves.
Lawrence Hrubes

The Real Lesson of the Stanford Prison Experiment - The New Yorker - 0 views

  • On the morning of August 17, 1971, nine young men in the Palo Alto area received visits from local police officers. While their neighbors looked on, the men were arrested for violating Penal Codes 211 and 459 (armed robbery and burglary), searched, handcuffed, and led into the rear of a waiting police car. The cars took them to a Palo Alto police station, where the men were booked, fingerprinted, moved to a holding cell, and blindfolded. Finally, they were transported to the Stanford County Prison—also known as the Stanford University psychology department.
  • And yet the lessons of the Stanford Prison Experiment aren’t so clear-cut. From the beginning, the study has been haunted by ambiguity. Even as it suggests that ordinary people harbor ugly potentialities, it also testifies to the way our circumstances shape our behavior. Was the study about our individual fallibility, or about broken institutions? Were its findings about prisons, specifically, or about life in general? What did the Stanford Prison Experiment really show?
Lawrence Hrubes

The Brain That Couldn't Remember - The New York Times - 0 views

  • In that pantheon of illuminatingly broken men and women, Henry stands apart. It is difficult to exaggerate the impact he has had on our understanding of ourselves. Before Brenda Milner collaborated on that first paper about Henry, the prevailing theory of memory held that its functions could not be localized to a single cortical area, that learning was distributed across the brain as a whole. By that theory — built upon the experimental lesioning of the brains of rats — a person’s memory would be affected only in proportion to the amount of brain tissue removed, regardless of which brain structures the tissue was removed from. Milner’s first paper about Henry, along with her previous work, upended this view.
  • Five years after Milner’s first paper about Henry, she published a second that was almost as revelatory. That paper documented Henry’s gradual improvement over a three-day period on a difficult hand-eye coordination task. His improvement came despite his inability to ever remember his previous attempts at the task, indicating that there are at least two different memory systems in the brain — one responsible for our conscious, episodic memories, the second responsible for task-or-skill related “procedural” memories — and that these two systems seem to rely on entirely distinct parts of the brain. This was another fundamental step forward in our understanding of how memory works. Together, Milner’s two Henry-­related revelations can be viewed as the cornerstones of modern memory science.
  • Corkin: Yeah, but it’s not peer-­reviewed, for one thing. That’s important. The stuff that’s published is good stuff. Peer-­reviewed. You can believe it. Things that, you know, experiments that might not have been good experiments, there might have been inadequate control groups. ... There are all sorts of things that can go wrong with experiments. Not every experiment is publishable.
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  • Me: But they can still be interpreted by other people. ... Maybe as we continue to understand how the brain works, and how memory works, some of this existing data of H.M.’s could be reilluminated by new theories, by new ideas, by new — it just seems a shame to destroy it. And it also seems — and this would be the darker interpretation of it — it locks in stone your own telling of H.M.’s story.
markfrankel18

Is Economics More Like History Than Physics? | Guest Blog, Scientific American Blog Net... - 3 views

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    "Is economics like physics, or more like history? Steven Pinker says, "No sane thinker would try to explain World War I in the language of physics." Yet some economists aim close to such craziness. Pinker says the "mindset of science" eliminates errors by "open debate, peer review, and double-blind methods," and especially, experimentation. But experiments require repetition and control over all relevant variables. We can experiment on individual behavior, but not with history or macroeconomics."
markfrankel18

Why we can 'see' the house that looks like Hitler | Science | The Observer - 0 views

  • had inadvertently rediscovered the remarkable human talent for perceiving meaning where there is none. Known as apophenia or pareidolia, it is something we all experience to some degree. We see faces in the clouds and animals in rock formations. We mishear our name being called in crowds and think our mobile phones are vibrating when it turns out to be nothing but the normal sensations of our own movement.
  • In many ways, this tendency is the basic ingredient of hallucination and it is present to a much stronger degree in people who have frank and striking hallucinations, most notably as part of the range of experiences that can accompany a diagnosis of schizophrenia.
  • Less clinically, the Swiss neuroscientist Peter Brugger has discovered that this tendency is raised in people who have greater numbers of supernatural beliefs and experiences but aren't unwell in any sense of the word. With increased apophenia, perhaps, the world just seems more imbued with meaning.
Lawrence Hrubes

Labs Are Told to Start Including a Neglected Variable: Females - NYTimes.com - 1 views

  • For decades, scientists have embarked on the long journey toward a medical breakthrough by first experimenting on laboratory animals. Mice or rats, pigs or dogs, they were usually male: Researchers avoided using female animals for fear that their reproductive cycles and hormone fluctuations would confound the results of delicately calibrated experiments.That laboratory tradition has had enormous consequences for women. Name a new drug or treatment, and odds are researchers know far more about its effect on men than on women. From sleeping pills to statins, women have been blindsided by side effects and dosage miscalculations that were not discovered until after the product hit the market.
markfrankel18

Why We Keep Playing the Lottery - Issue 4: The Unlikely - Nautilus - 1 views

  • Blind to the mathematical odds, we fall to the marketing gods.
  • “People just aren’t able to grasp 1 in 175 million,” Williams says. “It’s just beyond our experience—we have nothing in our evolutionary history that prepares us or primes us, no intellectual architecture, to try and grasp the remoteness of those odds.” And so we continue to play. And play.
  • It may seem easy to understand why we keep playing. As one trademarked lottery slogan goes, “Hey, you never know.” Somebody has to win. But to really understand why hundreds of millions of people play a game they will never win, a game with serious social consequences, you have to suspend logic and consider it through an alternate set of rules—rules written by neuroscientists, social psychologists, and economists. When the odds are so small that they are difficult to conceptualize, the risk we perceive has less to do with outcomes than with how much fear or hope we are feeling when we make a decision, how we “frame” and organize sets of logical facts, and even how we perceive ourselves in relation to others. Once you know the alternate set of rules, plumb the literature, and speak to the experts, the popularity of the lottery suddenly makes a lot more sense. It’s a game where reason and logic are rendered obsolete, and hope and dreams are on sale.
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  • Selling the lottery dream is possible because, paradoxically, the probabilities of winning are so infinitesimal they become irrelevant. Our brains didn’t evolve to calculate complex odds. In our evolutionary past, the ability to distinguish between a region with a 1 percent or 10 percent chance of being attacked by a predator wouldn’t have offered much of an advantage. An intuitive and coarse method of categorization, such as “doesn’t happen,” “happen sometimes,” “happens most of time,” “always happens,” would have sufficed, explains Jane L. Risen, an associate professor of Behavioral Science at the University of Chicago, Booth School of Business, who studies decision-making. Despite our advances in reason and mathematics, she says, we still often rely on crude calculations to make decisions, especially quick decisions like buying a lottery ticket.
  • In the conceptual vacuum created by incomprehensible odds, people are likely to experience magical thinking or superstition, play a hunch, or simply throw reason out the window all together, says George Loewenstein, a professor of economics and psychology at Carnegie Mellon. “Most of the weird stuff that you see with decision-making and risk happens with small probabilities,” he says.
  • But even fantasy will drop its hold on us if we always lose—a point Hargrove grasped from the start. Research has shown that positive reinforcement is a key in virtually all of the successful lotteries, notes the University of Lethbridge’s Williams. Lotteries that allow players to choose combinations of four or five numbers from a total of 60 numbers are popular, he says, because many players experience “the near miss,” which creates the illusion that they came close to winning the multi-million dollar jackpot. Most players don’t realize, however, that “near-miss” is an illusion. The odds of winning get worse with each successive match.
markfrankel18

The Berlin Wall's great human experiment - Ideas - The Boston Globe - 5 views

  • But before it fell, the wall did something that most people never think of: It created a massive laboratory for studying human society.Imagine this: If you were a researcher trying to determine how a political system affects people’s values, beliefs, and behavior, you would ideally want to take two identical populations, separate them for a generation or two, and subject them each to two totally different kinds of government. Then you’d want to measure the results, the same way a medical researcher might give two sets of patients two different pills and then track their progress.Ethically, such a study would be unthinkable even to propose. But when the Berlin Wall went up in 1961, it created what London School of Economics associate professor Daniel Sturm calls a “perfect experiment.”
Lawrence Hrubes

The Fake-Tongue Illusion - The New Yorker - 2 views

  • Michel and his co-authors put their magic tongue to use in a simple but provocative experiment, carried out late last year and described in the current issue of the scientific journal Perception. Although the involvement of a stretchy pink latex tongue makes it easy to mistake the experiment for a cheap gag, it’s actually an important addition to a distinguished tradition of psychological research that studies illusions for what they can reveal about how the brain constructs reality.
  • “A lot of my colleagues don’t want to think about the mouth and flavor,” he said. “They all want to study hearing and vision.” Spence’s work, by contrast, is concerned with how the brain combines input from multiple senses to create perception, and he regularly finds himself arguing for the importance of touch, taste, and smell in the construction of our day-to-day experiences. And, while the hand is limited to two senses, the tongue offers the possibility of testing four sensory modes: touch, sight, taste, and smell (through a process called retronasal olfaction).
markfrankel18

Study delivers bleak verdict on validity of psychology experiment results | Science | T... - 1 views

  • A major investigation into scores of claims made in psychology research journals has delivered a bleak verdict on the state of the science. An international team of experts repeated 100 experiments published in top psychology journals and found that they could reproduce only 36% of original findings.
Lawrence Hrubes

A mouse's house may ruin experiments : Nature News & Comment - 0 views

  • It’s no secret that therapies that look promising in mice rarely work in people. But too often, experimental treatments that succeed in one mouse population do not even work in other mice, suggesting that many rodent studies may be flawed from the start.
markfrankel18

'Son of Saul,' Kierkegaard and the Holocaust - NYTimes.com - 0 views

  • There are generally two, radically different ways to relate to the world: objective and subjective. Objectivity is an orientation towards reality based on abstracting away, in various degrees, from subjective experience, and from individual points of view. A subjective orientation, on the other hand, is based on an attunement to the inner experience of feeling, sensing, thinking and valuing that unfolds in our day-to-day living. This distinction has been brought into contemporary philosophical discourse most notably by Thomas Nagel, in a number of his essays, most famously in “What Is It Like to Be a Bat?”The spectacular success of science in the past 300 years has raised hopes that it also holds the key to guiding human beings towards a good life. Psychology and neuroscience has become a main source of life advice in the popular media. But philosophers have long held reservations about this scientific orientation to how to live life. The 18th century Scottish philosopher David Hume, for instance, famously pointed out, no amount of fact can legislate value, moral or otherwise. You cannot derive ought from is. But there is another, in some way more radical concern, expressed in Western philosophy most forcefully by Kierkegaard, and in literature by Dostoyevsky — two religiously inspired thinkers — namely that our experience of life matters in ineffable ways that no objective understanding of the world can capture.
Lawrence Hrubes

The Excrement Experiment - The New Yorker - 0 views

  • Crohn’s disease affects as many as seven hundred thousand Americans, but, like other autoimmune disorders, it remains poorly understood and is considered incurable. (Autoimmune disorders are thought to arise when the immune system attacks healthy tissue, mistaking it for a threat.) The standard treatments for Crohn’s often don’t work, or work only temporarily, and many have serious side effects.
  • His mother showed him an article from the Times about a man who had been nearly bedridden by ulcerative colitis—a condition related to Crohn’s—and who had largely recovered after a month or so of fecal transplants. Gravel found a how-to book on Amazon and bought the recommended equipment: a blender, a rectal syringe, saline solution, surgical gloves, Tupperware containers. His wife agreed to be his donor.
  • New research suggests that the microbes in our guts—and, consequently, in our stool—may play a role in conditions ranging from autoimmune disorders to allergies and obesity, and reports of recoveries by patients who, with or without the help of doctors, have received these bacteria-rich infusions have spurred demand for the procedure. A year and a half ago, a few dozen physicians in the United States offered FMT. Today, hundreds do, and OpenBiome, a nonprofit stool bank founded last year by graduate students at M.I.T., ships more than fifty specimens each week to hospitals in thirty-six states. The Cleveland Clinic named fecal transplantation one of the top ten medical innovations for 2014, and biotech companies are competing to put stool-based therapies through clinical trials and onto the market. In medicine, at any rate, human excrement has become a precious commodity.
markfrankel18

"Laurel" versus "Yanny" is a timely reminder that all human experience is subjective, m... - 0 views

  • The Dress and Yanny/Laurel blow our collective minds because we’re surprised when other people perceive the world differently than we do. And that suggests we’re still attached to the idea that our version of reality is the correct and only one. Nothing could be further from the truth. “It is a fact of neuroscience that everything we experience is a figment of our imagination,”
markfrankel18

Flossing and the Art of Scientific Investigation - The New York Times - 1 views

  • As the doctor Mark Tonelli has argued, distinct forms of knowledge can’t be judged by the same standards: what a patient prefers on the basis of personal experience; what a doctor thinks on the basis of clinical experience; and what clinical research has discovered — each of these is valuable in its own way. While scientists concur that randomized trials are ideal for evaluating the average effects of treatments, such precision isn’t necessary when the benefits are obvious or clear from other data.
  • Distrusting expertise makes it easy to confuse an absence of randomized evaluations with an absence of knowledge. And this leads to the false belief that knowledge of what works in social policy, education or fighting terrorism can come only from randomized evaluations. But by that logic (as a spoof scientific article claimed), we don’t know if parachutes really work because we have no randomized controlled trials of them.
  • Experiments, of course, are invaluable and have, in the past, shown the consensus opinion of experts to be wrong. But those who fetishize this methodology, as the flossing example shows, can also impair progress toward the truth. A strong demand for evidence is a good thing. But nurturing a more nuanced view of expertise should be part of that demand.
Lawrence Hrubes

If Animals Have Rights, Should Robots? - The New Yorker - 0 views

  • People projected thoughts into Harambe’s mind. “Our tendency is to see our actions through human lenses,” a neuroscientist named Kurt Gray told the network as the frenzy peaked. “We can’t imagine what it’s like to actually be a gorilla. We can only imagine what it’s like to be us being a gorilla.” This simple fact is responsible for centuries of ethical dispute. One Harambe activist might believe that killing a gorilla as a safeguard against losing human life is unjust due to our cognitive similarity: the way gorillas think is a lot like the way we think, so they merit a similar moral standing. Another might believe that gorillas get their standing from a cognitive dissimilarity: because of our advanced powers of reason, we are called to rise above the cat-eat-mouse game, to be special protectors of animals, from chickens to chimpanzees. (Both views also support untroubled omnivorism: we kill animals because we are but animals, or because our exceptionalism means that human interests win.) These beliefs, obviously opposed, mark our uncertainty about whether we’re rightful peers or masters among other entities with brains.
  • The big difference, they argue, is “sentience.” Many animals have it; zygotes and embryos don’t. Colb and Dorf define sentience as “the ability to have subjective experiences,” which is a little tricky, because animal subjectivity is what’s hard for us to pin down. A famous paper called “What Is It Like to Be a Bat?,” by the philosopher Thomas Nagel, points out that even if humans were to start flying, eating bugs, and getting around by sonar they would not have a bat’s full experience, or the batty subjectivity that the creature had developed from birth.
  • If animals suffer, the philosopher Peter Singer noted in “Animal Liberation” (1975), shouldn’t we include them in the calculus of minimizing pain? Such an approach to peership has advantages: it establishes the moral claims of animals without projecting human motivations onto them. But it introduces other problems. Bludgeoning your neighbor is clearly worse than poisoning a rat.
Lawrence Hrubes

WAYS OF SEEING HISTORY - 0 views

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    "Let me first offer a simple definition of history. History is a story about the past that is both true and significant. We might quibble about the word "story" and prefer "account" or "report". Some also might be cynical about the word "true". Here I take truth to mean closest possible correspondence to what actually happened. What is truth, after all? As we answer that question, I would caution against both facile dogmatism and stylish cynicism. The human experience of truth is complex but definite."
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