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Duane Sharrock

Tissue engineering: Growing new organs, and more - MIT News Office - 0 views

  • This kind of disease modeling could have a great impact in the near term, says MIT professor Sangeeta Bhatia, who is developing liver tissue to study hepatitis C and malaria infection.
  • liver is difficult to grow outside the human body because cells tend to lose their function when they lose contact with neighboring cells. “
  • In a large-scale project recently funded by the Defense Advanced Research Projects Administration, several MIT faculty members are working on a “human-on-a-chip” system that scientists could use to study up to 10 human tissue types at a time.
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  • Biological and Mechanical Engineering
  • developing regenerative therapies that help promote wound healing.
  • Endothelial cells, normally found lining blood vessels, could help repair damage caused by angioplasty or other surgical interventions; smoke inhalation; and cancer or cardiovascular disease.
  • One of the earliest successes of implantable tissues was the development of artificial skin, which is now commonly used to treat burn victims.
  • Langer is now working on more complex tissues, such as cardiac-tissue scaffolds that include electronic sensors and a synthetic polymer that could restore vocal-cord function in people who have lost their voices through overuse or other types of damage
  • In Bhatia’s lab, where tissue-engineering research is evenly divided between modeling diseases and working toward implantable organs, researchers recently developed 3-D liver tissues that include their own network of blood vessels
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    "MIT News examines research with the potential to reshape medicine and health care through new scientific knowledge, novel treatments and products, better management of medical data, and improvements in health-care delivery. "
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    "MIT News examines research with the potential to reshape medicine and health care through new scientific knowledge, novel treatments and products, better management of medical data, and improvements in health-care delivery. "
Duane Sharrock

Medical devices powered by the ear itself - MIT News Office - 0 views

  • Health Sciences and Technology (HST) demonstrate for the first time that this battery could power implantable electronic devices without impairing hearing.
  • The devices could monitor biological activity in the ears of people with hearing or balance impairments, or responses to therapies. Eventually, they might even deliver therapies themselves
  • “In the past, people have thought that the space where the high potential is located is inaccessible for implantable devices, because potentially it’s very dangerous if you encroach on it,” Stankovic says. “We have known for 60 years that this battery exists and that it’s really important for normal hearing, but nobody has attempted to use this battery to power useful electronics.”
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  • The ear converts a mechanical force — the vibration of the eardrum — into an electrochemical signal that can be processed by the brain; the biological battery is the source of that signal’s current. Located in the part of the ear called the cochlea, the battery chamber is divided by a membrane, some of whose cells are specialized to pump ions. An imbalance of potassium and sodium ions on opposite sides of the membrane, together with the particular arrangement of the pumps, creates an electrical voltage.
  • Low-power chips, however, are precisely the area of expertise of Anantha Chandrakasan’s group at MTL
  • The frequency of the signal was thus itself an indication of the electrochemical properties of the inner ear.
  • in cochlear implants, diagnostics and implantable hearing aids. “The fact that you can generate the power for a low voltage from the cochlea itself raises the possibility of using that as a power source to drive a cochlear implant,” Megerian says. “Imagine if we were able to measure that voltage in various disease states. There would potentially be a diagnostic algorithm for aberrations in that electrical output.”
  • “I’m not ready to say that the present iteration of this technology is ready,” Megerian cautions. But he adds that, “If we could tap into the natural power source of the cochlea, it could potentially be a driver behind the amplification technology of the future.”
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    "For the first time, researchers power an implantable electronic device using an electrical potential - a natural battery - deep in the inner ear."
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    "All of D-Lab's classes assess the needs of people in less-privileged communities around the world, examining innovations in technology, education or communications that might address those needs. The classes then seek ways to spread word of these solutions - and in some cases, to spur the creation of organizations to help disseminate them. Specific projects have focused on improved wheelchairs and prosthetics; water and sanitation systems; and recycling waste to produce useful products, including charcoal fuel made from agricultural waste."
thinkahol *

Medical Daily: Reproductive scientists create mice from 2 fathers - 0 views

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    Using stem cell technology, reproductive scientists in Texas, led by Dr. Richard R. Berhringer at the M.D. Anderson Cancer Center, have produced male and female mice from two fathers.
thinkahol *

The Healing Power of Light - Technology Review - 0 views

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    A polymer that mends itself could lead to medical implants or engine parts that fix themselves.
dev j

Online editing services - 0 views

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    Welcome to Manuscriptedit.com, your online partner for English language editing, proofreading, medical writing, formatting, design & development and publication support services. We offer a comprehensive manuscript editing service before its submission for publication as well as after acceptance by the peer review process.
tabnova914

How do healthcare MDM solutions adapt to the unique needs and workflows of healthcare s... - 3 views

Healthcare Master Data Management (MDM) solutions demonstrate remarkable adaptability to accommodate the distinctive requirements and intricacies of healthcare environments, which encompass a wide ...

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