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thinkahol *

Mass-producing stem-cells for stem cells for diagnostic and therapeutic applications | ... - 0 views

www.kurzweilai.net/c-and-therapeutic-applications

Mass-producing stem-cells for stem cells diagnostic and therapeutic applications | KurzweilAI

shared by thinkahol * on 21 Jun 11 - No Cached
  • thinkahol * on 21 Jun 11
     
    Todd McDevitt at the Georgia Institute of Technology and colleagues have found that adding biomaterials such as gelatin into clumps of stem cells (called "embryoid bodies") affected stem-cell differentiation without harming the cells. By incorporating magnetic particles into the biomaterials, they could control the locations of the embryoid bodies and how they assemble with one another. Compared to typical delivery methods, providing differentiation factors - retinoic acid, bone morphogenetic protein 4 (BMP4) and vascular endothelial growth factor (VEGF) - via microparticles induced changes in the gene and protein expression patterns of the aggregates. In the future, these new methods could be used to develop manufacturing procedures for producing large quantities of stem cells for diagnostic and therapeutic applications. The findings were presented on June 16 at the annual meeting of the International Society for Stem Cell Research. [full text]
thinkahol *

Erasing signs of aging in human cells now a reality - 0 views

www.sciencedaily.com/...111103120605.htm

Erasing signs of aging in human cells now a reality

shared by thinkahol * on 07 Nov 11 - No Cached
  • thinkahol * on 07 Nov 11
     
    ScienceDaily (Nov. 3, 2011) - Scientists have recently succeeded in rejuvenating cells from elderly donors (aged over 100). These old cells were reprogrammed in vitro to induced pluripotent stem cells (iPSC) and to rejuvenated and human embryonic stem cells (hESC): cells of all types can again be differentiated after this genuine "rejuvenation" therapy. The results represent significant progress for research into iPSC cells and a further step forwards for regenerative medicine.
thinkahol *

Medical Daily: Reproductive scientists create mice from 2 fathers - 0 views

www.medicaldaily.com/...create-mice-from-2-fathers.htm

Medical Daily: Reproductive scientists create mice from 2 fathers

shared by thinkahol * on 12 Dec 10 - No Cached
  • thinkahol * on 12 Dec 10
     
    Using stem cell technology, reproductive scientists in Texas, led by Dr. Richard R. Berhringer at the M.D. Anderson Cancer Center, have produced male and female mice from two fathers.
Duane Sharrock

Tissue engineering: Growing new organs, and more - MIT News Office - 0 views

www.mit.edu/...ering-growing-organs-1214.html

tissue engineering growing mit office scaffolding Sangeeta Bhatia regeneration replacement organ skin stem cells

shared by Duane Sharrock on 21 Dec 12 - No Cached
  • This kind of disease modeling could have a great impact in the near term, says MIT professor Sangeeta Bhatia, who is developing liver tissue to study hepatitis C and malaria infection.
  • liver is difficult to grow outside the human body because cells tend to lose their function when they lose contact with neighboring cells. “
  • In a large-scale project recently funded by the Defense Advanced Research Projects Administration, several MIT faculty members are working on a “human-on-a-chip” system that scientists could use to study up to 10 human tissue types at a time.
  • ...6 more annotations...
  • Biological and Mechanical Engineering
  • developing regenerative therapies that help promote wound healing.
  • Endothelial cells, normally found lining blood vessels, could help repair damage caused by angioplasty or other surgical interventions; smoke inhalation; and cancer or cardiovascular disease.
  • One of the earliest successes of implantable tissues was the development of artificial skin, which is now commonly used to treat burn victims.
  • Langer is now working on more complex tissues, such as cardiac-tissue scaffolds that include electronic sensors and a synthetic polymer that could restore vocal-cord function in people who have lost their voices through overuse or other types of damage
  • In Bhatia’s lab, where tissue-engineering research is evenly divided between modeling diseases and working toward implantable organs, researchers recently developed 3-D liver tissues that include their own network of blood vessels
  • Duane Sharrock on 21 Dec 12
     
    "MIT News examines research with the potential to reshape medicine and health care through new scientific knowledge, novel treatments and products, better management of medical data, and improvements in health-care delivery. "
  • Duane Sharrock on 21 Dec 12
     
    "MIT News examines research with the potential to reshape medicine and health care through new scientific knowledge, novel treatments and products, better management of medical data, and improvements in health-care delivery. "
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