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The global spread of the H5N1 avian influenza has already extensively damaged economies worldwide and food security in developing countries. The spread of infection to new ecosystems results in viral adaptation to new hosts, including humans, which inevitably amplifies the potential for pandemic flu. H5N1 represents an unprecedented model of how influenza infections may become widespread. It is recognized that avian influenza viruses may be the progenitors of the next human pandemic virus, and for this reason their genetic evolution should be monitored and investigated in a timely manner. The full support of the international scientific community is therefore urgently required to better understand the spread and evolution of the virus, and the determinants of its transmissibility and pathogenicity in humans. This in turn demands that scientists with different fields of expertise have full access to comprehensive genetic sequence, clinical, and epidemiological data from both animal and human virus isolates.

Using homemade lab equipment and the wealth of scientific knowledge available online, these hobbyists are trying to create new life forms through genetic engineering - a field long dominated by Ph.D.s toiling in university and corporate laboratories.

This habitat of excellence is designed and maintained by scientists for scientists from various disciplines e.g. veterinary and human virology, bioinformatics, epidemiology, immunology and clinical analysis etc. From here on, you will find a series of services, starting with our EpiFlu Database (led by the Swiss Institute of Bioinformatics) providing secure storage and the analysis of genetic, epidemiological and clinical data.

An international research consortium has been formed to create the most detailed and medically useful picture to date of human genetic variation. The 1000 Genomes Project will involve sequencing the genomes of at least a thousand people from around the world. The project will receive major support from the Wellcome Trust Sanger Institute in Hinxton, England, the Beijing Genomics Institute Shenzhen in China and the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH).

We believe individuals from the general public have a vital role to play in making personal genomes useful. We are recruiting volunteers who are willing to share their genome sequence and many types of personal information with the research community and the general public, so that together we will be better able to advance our understanding of genetic and environmental contributions to human traits and to improve our ability to diagnose, treat, and prevent illness. Learn more about how to participate in the Personal Genome Project.

As cultures and languages vanish, along with them go vast and ancient storehouses of accumulated knowledge. And as species disappear, along with them go not just valuable genetic resources, but critical links in complex ecological webs.

The Tree of Life Web Project (ToL) is a collaborative effort of biologists and nature enthusiasts from around the world. On more than 10,000 World Wide Web pages, the project provides information about biodiversity, the characteristics of different groups of organisms, and their evolutionary history (phylogeny). Each page contains information about a particular group, e.g., salamanders, segmented worms, phlox flowers, tyrannosaurs, euglenids, Heliconius butterflies, club fungi, or the vampire squid. ToL pages are linked one to another hierarchically, in the form of the evolutionary tree of life. Starting with the root of all Life on Earth and moving out along diverging branches to individual species, the structure of the ToL project thus illustrates the genetic connections between all living things.

WikiGenes is the first wiki system to combine the collaborative and largely altruistic possibilities of wikis with explicit authorship. In view of the extraordinary success of Wikipedia there remains no doubt about the potential of collaborative publishing, yet its adoption in science has been limited. Here I discuss a dynamic collaborative knowledge base for the life sciences that provides authors with due credit and that can evolve via continual revision and traditional peer review into a rigorous scientific tool.

A Resource for Comparative Grass Genomics

Ensembl is a joint project between EMBL - EBI and the Sanger Institute to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes. Ensembl is primarily funded by the Wellcome Trust. This site provides free access to all the data and software from the Ensembl project. Click on a species name to browse the data.

PHYLIP is a free package of programs for inferring phylogenies. It is distributed as source code, documentation files, and a number of different types of executables.

The International HapMap Project is a partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States to develop a public resource that will help researchers find genes associated with human disease and response to pharmaceuticals.