Skip to main content

Home/ Groups/ Dr. Goodyear
Rss Feed
Sort By: Most Recent | Popular Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

http://www.anaturalhealingcenter.com/documents/Thorne/articles/scleroderma11-3.pdf - 0 views

www.anaturalhealingcenter.com/...scleroderma11-3.pdf

scleroderma vitamin E vitamin E natural therapy treatment autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    Review of the science that support natural therapies in scleroderma.
Nathan Goodyear

http://www.clinexprheumatol.org/article.asp?a=496 - 0 views

www.clinexprheumatol.org/article.asp

scleroderma vitamin E vitamin E autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    pilot study finds that topical vitamin E benefits healing of digital ulcers, reduced healing time and pain.
Nathan Goodyear

Progressive systemic sclerosis and S-adenosylmethionine. - ResearchGate - 0 views

www.researchgate.net/...rosis_and_S-adenosylmethionine

scleroderma SAMe S-adenosyl-L-methionine autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    This study used IV SAMe at 600 mg daily for 2 months and then followed up with 400 mg TID and found significant improvement in skin findings.
Nathan Goodyear

http://ajcn.nutrition.org/content/76/5/1151S.full.pdf - 0 views

ajcn.nutrition.org/...1151S.full.pdf

SAMe S-adenosyl-L-methionine

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    Great review article on SAMe.
Nathan Goodyear

Evening primrose oil (Efamol) in the treatmen... [Thromb Haemost. 1985] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...4082084

evening primrose oil Raynaud's GLA Gamma-linolenic acid

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    patients given 6 grams of Evening primrose oil had improvement in Raynaud's symptoms in 8 weeks.
Nathan Goodyear

Systemic sclerosis: environmental factors. [J Rheumatol. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19797508

scleroderma environmental toxin toxins autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    Environmental toxins such as slice and organic solvents have been associated with the development of scleroderma.  Other exposures include bacterial, viral, pesticides, prescription drugs...
Nathan Goodyear

Epidemiology of Systemic Sclerosis - 0 views

www.medscape.com/...758480

scleroderma silica environmental toxins toxin autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    silica exposure plays a role in the development of scleroderma
Nathan Goodyear

T cells in systemic sclerosis: a reappraisal. - ResearchGate - 0 views

www.researchgate.net/...stemic_sclerosis_a_reappraisal

scleroderma IL-6 autoimmune disease cytokines

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    Article looks at the role of IL-6 in fibrosis in scleroderma.  The fibrosis in scleroderma appears to be a Th2 driven process.
Nathan Goodyear

http://rheumatology.oxfordjournals.org/content/49/11/2024.full.pdf - 0 views

rheumatology.oxfordjournals.org/...2024.full.pdf

EGCG epigallocatechin-3-gallate green tea NF-kappaB inflammation scleroderma autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    EGCG found to reduce extra cellular matrix production, fibrosis, and NF-kappaB activity in those with scleroderma.
Nathan Goodyear

Modulation of Fibrosis in Systemic Sclerosis by Nitric Oxide and Antioxidants - 0 views

www.hindawi.com/...521958

scleroderma EGCG epigallocatechin-3-gallate green tea autoimmune disease oxidative stress sclerosis inflammation antioxidants

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    Animal and human study finds protection against fibrosis with EGCG in those with scleroderma.
Nathan Goodyear

Serum 25OH vitamin D concentrations are linked with various clinical aspects in patient... - 0 views

www.researchgate.net/...y_and_review_of_the_literature

vitamin d vitamin D scleroderma autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    Vitamin D levels inversely associated with fibrosis in scleroderma.
Nathan Goodyear

20S-hydroxyvitamin D3, noncalcemic product of CYP11A1 action on vitamin D3, exhibits po... - 0 views

europepmc.org/...23295467

scleroderma vitamin D vitamin d inflammation autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    vitamin D decreased fibrogenesis in invivo mouse model of scleroderma.
Nathan Goodyear

Egr-ly awaiting a "personalized medicine" approach to treat scleroderma - 0 views

www.ncbi.nlm.nih.gov/...PMC3368023

morphea

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    morphea
Nathan Goodyear

Morphea subtypes are distinct autoimmune syndromes: A review of 245 adult and pediatric... - 0 views

www.ncbi.nlm.nih.gov/...PMC2938024

morphea autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    morphea 
Nathan Goodyear

Updates on Morphea: Role of Vascular Injury and Advances in Treatment - 0 views

www.ncbi.nlm.nih.gov/...PMC3844232

morphea autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    morphea
Nathan Goodyear

Interleukin-17A and interleukin-23 in morphea - 0 views

www.ncbi.nlm.nih.gov/...PMC3542501

morphea cytokines inflammation scleroderma autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    More discussion of morphea and the cytokine presentation.
Nathan Goodyear

Cytokine profiles in localized scleroderma and relationship to clinical features - 0 views

www.ncbi.nlm.nih.gov/...PMC3632442

morphea autoimmune disease children scleroderma inflammation

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Evaluation of the literature reveals a Th2 predominant cytokine profile in the biological specimens (sera, PBMCs, and tissue) of those with SSc
  • the literature available from studies in LS show that Th1, Th2, and Th17 cytokines may contribute equally to the pathogenesis of the disease
  • Classically, Th1 cells have been known to secrete IL-2, IFN-γ, and TNF-α, and are stimulated by IL-2 and IL-12
  • ...3 more annotations...
  • Th2 cells have been shown to be activated by IL-4 and produce IL-4, IL-5, IL-10 and IL-13
  • Th17 cells, a more recently identified Th cell subset that has altered the classic Th1/Th2 paradigm, produce IL-17 A/F, IL-21, and IL-22. IL-1, IL-6, IL-23, and TGF-β are now known to play important roles in the differentiation and propagation of the Th17 cell lineage
  • there is an overall notion that pro-inflammatory Th1 and Th17 associated cytokines are elevated during the early stages of scleroderma, whereas Th2 cytokines mainly correlate with disease damage and fibrosis extent
  • Nathan Goodyear on 22 Jan 14
     
    morphea
Nathan Goodyear

Estrogen receptor β2 and β5 are associated with poor prognosis in prostate ca... - 0 views

erc.endocrinology-journals.org/...675.short

ER beta ER-beta estrogen receptor receptors prostate cancer

shared by Nathan Goodyear on 21 Jan 14 - No Cached
  • Nathan Goodyear on 21 Jan 14
     
    Study finds that ER beta isomer type 2 and 4 increased prostate cancer aggressiveness.
Nathan Goodyear

The androgen metabolite 5alpha-androstane-3beta,17beta-diol (3betaAdiol) induces breast... - 0 views

www.researchgate.net/...aromatase_inhibitor_resistance

breast cancer aromatase aromatase inhibitors estradiol estrogen 3-beta androstanediol Testosterone DHT 3 beta HSD receptor receptors ER alpha ER-alpha ER beta ER-beta hormone hormones women

shared by Nathan Goodyear on 21 Jan 14 - No Cached
  • Nathan Goodyear on 21 Jan 14
     
    Great article!!  Nice discussion of the complexity of hormones.  Women on aromatase inhibitors can make estrogen from Testosterone.  This is important with estrogen sensitive cancer as in breast cancer.  This will occur via alternative pathways: Testosterone to DHT via 5 alpha reductase and then DHT to 3 beta androstanediol via 3 beta HSD.  3 beta androstanediol is a male hormone metabolite that binds to estrogen receptors.  The affinity is less than Estradiol, but appears to have a higher affinity for ER beta over ER alpha. 
« First ‹ Previous 7121 - 7140 of 11105 Next › Last »
Showing 20▼ items per page
Join this group