Skip to main content

Home/ Dr. Goodyear/ Group items tagged morphea

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

Updates on Morphea: Role of Vascular Injury and Advances in Treatment - 0 views

www.ncbi.nlm.nih.gov/...PMC3844232

morphea autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    morphea
Nathan Goodyear

Interleukin-17A and interleukin-23 in morphea - 0 views

www.ncbi.nlm.nih.gov/...PMC3542501

morphea cytokines inflammation scleroderma autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    More discussion of morphea and the cytokine presentation.
Nathan Goodyear

Morphea subtypes are distinct autoimmune syndromes: A review of 245 adult and pediatric... - 0 views

www.ncbi.nlm.nih.gov/...PMC2938024

morphea autoimmune disease

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    morphea 
Nathan Goodyear

JAMA Network | JAMA Dermatology | Oral Calcitriol as a New Therapeutic Modality for Gen... - 0 views

archderm.jamanetwork.com/article.aspx

vitamin D vitamin D morphea autoimmune disease inflammation scleroderma

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    vitamin D therapy in small study of children with morphea found significant improvement with skin and joint mobility.  The dosing was small and duration of therapy was only up to 7 months.  The benefits was found to extend to up to 2 years.
Nathan Goodyear

Cytokine profiles in localized scleroderma and relationship to clinical features - 0 views

www.ncbi.nlm.nih.gov/...PMC3632442

morphea autoimmune disease children scleroderma inflammation

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Evaluation of the literature reveals a Th2 predominant cytokine profile in the biological specimens (sera, PBMCs, and tissue) of those with SSc
  • the literature available from studies in LS show that Th1, Th2, and Th17 cytokines may contribute equally to the pathogenesis of the disease
  • Classically, Th1 cells have been known to secrete IL-2, IFN-γ, and TNF-α, and are stimulated by IL-2 and IL-12
  • ...3 more annotations...
  • Th2 cells have been shown to be activated by IL-4 and produce IL-4, IL-5, IL-10 and IL-13
  • Th17 cells, a more recently identified Th cell subset that has altered the classic Th1/Th2 paradigm, produce IL-17 A/F, IL-21, and IL-22. IL-1, IL-6, IL-23, and TGF-β are now known to play important roles in the differentiation and propagation of the Th17 cell lineage
  • there is an overall notion that pro-inflammatory Th1 and Th17 associated cytokines are elevated during the early stages of scleroderma, whereas Th2 cytokines mainly correlate with disease damage and fibrosis extent
  • Nathan Goodyear on 22 Jan 14
     
    morphea
Nathan Goodyear

Egr-ly awaiting a "personalized medicine" approach to treat scleroderma - 0 views

www.ncbi.nlm.nih.gov/...PMC3368023

morphea

shared by Nathan Goodyear on 22 Jan 14 - No Cached
  • Nathan Goodyear on 22 Jan 14
     
    morphea
Nathan Goodyear

Deep Morphea after Vaccination in Two Young Children - Torrelo - 2006 - Pediatric Derma... - 0 views

onlinelibrary.wiley.com/...abstract

vaccines vaccine vaccination children pediatric morpheme

shared by Nathan Goodyear on 15 Jan 14 - No Cached
  • Nathan Goodyear on 15 Jan 14
     
    Vaccines linked to morphea in 2 case studies.  The mechanism is through autoimmune activation.
Nathan Goodyear

Post Vaccination Morphea in a Child | KUMAR | Journal of Pediatric Sciences (ISSN:1309-... - 0 views

www.pediatricsciences.com/...index.php

vaccination vaccine children morphea

shared by Nathan Goodyear on 15 Jan 14 - No Cached
  • Nathan Goodyear on 15 Jan 14
     
    proposed morpheme induced by vaccination.  Possible autoimmune initiation.
1 - 8 of 8
Showing 20▼ items per page