Harriet Lane Handbook: Progesterone regulates the phosphorylation of protein phosphatases in the brain. - 0 views
-
Nathan Goodyear on 11 Mar 14rat model finds that progesterone effects internal cell enzyme activity. In this case, progesterone increased PP2A in the cerebellum and in the hyippocampus. Interesting, that E2 priming decreased the effects on the hippocampus, but not the cerebellum. This reveals a biochemical link between sex hormones, progesterone in this case, and the brain. Studies have shown progesterone to be neuroprotective in TBI. This may be one mechanism.