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Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communica...
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www.cell.com/...S0092-8674(13)01521-3
NAD
mitochondria
disease
aging
sirloins
SIRT
SIRT1
HIF-1alpha
shared by
Nathan Goodyear
on 07 Jun 16
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Nathan Goodyear
on 07 Jun 16
NAD found to slow mitochondrial decline associated with aging. SIRT1 is involved; interesting of note is the inverse association with HIF-1alpha
NAD found to slow mitochondrial decline associated with aging. SIRT1 is involved; interesting of note is the inverse association with HIF-1alpha
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Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to incr...
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stke.sciencemag.org/...ra106.abstract
nitric oxide
NO
inflammation
SIRT1
sirloins
disease
aging
shared by
Nathan Goodyear
on 19 Nov 14
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Nathan Goodyear
on 19 Nov 14
Nitic Oxide (NO) via inflammation deactivates SIRT1 is a common finding in inflammatory diseases of aging, proposes authors of this paper.
Nitic Oxide (NO) via inflammation deactivates SIRT1 is a common finding in inflammatory diseases of aging, proposes authors of this paper.
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