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Nathan Goodyear

Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis:... - 0 views

  • in addition to the type of diet being a modulator of microbiota composition, the timing of food intake plays a critical role in shaping intestinal microbial ecology.
  • the microbiota rhythms are influenced by the host clock and perform critical functions in the adaptation of metabolic processes to the diurnal fluctuations in the environment
  • Our study reveals that dysbiosis has a temporal dimension and that static microbiota comparisons might not be fully conclusive unless samples were taken in a controlled manner with respect to this important additional variable
  • ...1 more annotation...
  • our taxonomic analysis indicates that microbiota oscillations are following rhythmic food intake
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    This is a really nice study.  Altered sleep-wake cycles result in altered food consumption which leads to altered gut microbiota diurnal oscillations.  Gut microbiota have a normal diurnal oscillation.  This altered gut flora then leads to increase insulin resistance, metabolic syndrome, diabetes...
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